“Ftivazide” is a drug whose action is aimed at combating tuberculosis. The medication is produced in tablet form. The following active substance is contained in the drug - phtivazide. Tablets are placed in blisters of ten or one hundred pieces.
pharmachologic effect
According to the instructions for use with Ftivazidom, it is known that the drug belongs to anti-TB drugs, derivatives of isonicotinic acid hydrazide. The medication exhibits increased activity against tuberculosis mycobacteria.
The use of “Ftivazide” inhibits metabolic and oxidative processes, which leads to a violation of the membrane of mycobacteria. In addition, the drug inhibits the connection of nucleic acids, and also has an effect on mycobacteria at all levels.
Indications and contraindications
The drug is prescribed to eliminate all forms of tuberculosis in children and adults. The instructions for use with Ftivazide tablets indicate the following limitations:
- Epilepsy (a chronic neurological disease that is characterized by a predisposition of the body to a sharp onset of seizures).
- Angina pectoris (a common heart disease that, with progression, leads to chronic heart failure and myocardial infarction).
- Increased drug sensitivity.
- Chronic heart disease.
- Diseases of the kidneys or liver.
- Organic lesions of the central nervous system.
- Alcoholism.
- Chronic kidney disease.
- Children's age up to one year.
According to the instructions to "Ftivazid", tablets during an "interesting situation" should be used with extreme caution, given the benefits to the mother and the likely risk to the unborn baby. When using the drug should stop breastfeeding and transfer the baby to the mixture.
Mode of application
The drug is taken orally. As a rule, the dosage for adult patients is 5 tablets three times a day.
According to the instructions for use with Ftivazidom, children calculate the concentration of the drug, based on the calculation of 30-40 milligrams per kilogram of weight per day. The dose received must be divided into three uses.
According to the instructions, it is known that with lupus tuberculosis, the dosage is 3 tablets four times a day. The duration of therapy varies from one to one and a half months. If necessary, you can undergo re-treatment after a break. Maximum dosage of medication for adult patients and children:
- single - 10 tablets;
- daily - 20 tablets;
- for children, the daily dose is 15 tablets.
What side effects may occur after taking the drug
According to reviews and instructions for use with Ftivazid, it is known that the medicine can provoke the following negative phenomena:
- Vertigo (dizziness - a symptom known as dizziness, it is characteristic of ear pathology or, less commonly, brain damage).
- Euphoria (positively colored affect or emotion).
- Migraine (a neurological disease that is characterized by periodic or constant bouts of headache on one side).
- Fatigue.
- Memory loss.
- Sleep disturbance.
- Depression (a mental disorder whose main symptoms are a decreased mood and a decrease or loss in the ability to have fun).
- Psychosis (pronounced severe disorder of a psychotic level).
- Arthralgia (a pathological disease that is characterized by the occurrence of intense pain both in one joint and in several at once).
- Optic neuritis (inflammation of the eye, which provokes a strong decrease in visual acuity).
- Peripheral neuritis (an inflammatory disease of the peripheral nerves that leads to structural changes in the nervous tissue).
- Decreased appetite.
What other negative effects are there
A medicine with improper dosage can provoke certain side effects, for example, such:
- Vomiting.
- Dry mouth.
- Nausea.
- Hepatitis (diffuse inflammation of the liver tissue due to a toxic, infectious or autoimmune process).
- Epigastric pain.
- Increased bleeding.
- Cardialgia (a pathology that is characterized by the appearance of pain in the left side of the chest).
- Skin rash.
- Fever.
- Gastralgia (an unpleasant sensation that is associated with a real or possible disruption of the stomach).
- Menorrhagia (blood loss during menstruation, exceeding the physiological norm).
- Gynecomastia (a pathological condition of the mammary glands in men, which is manifested by an increase in their size due to hypertrophy of glandular or adipose tissue).
According to reviews, it is known that “Ftivazide” in people who suffer from epilepsy can provoke a more frequent occurrence of epileptic seizures.
Drug interaction
According to the instructions, "Ftivazide" enhances the side effects of alcoholic beverages, "Paracetamol", "Carbamazepine", "Benzodiazepines", as well as hepatoxic drugs.
In addition, the drug enhances the effect of antiplatelet agents and anticoagulants, reduces the effect of glucocorticoids and mineralocorticoids. The absorption of the drug is slowed down by antacids.
Analogs
Like any other medication, Ftivazid has a number of substitutes:
- Isoniazid.
- "Bedaquiline."
- "Capreomycin."
- "Protionamide".
- "Viomycin."
- Ethambutol.
- "Cycloserine."
- "Pyrazinamide."
- Therizidone.
- "Metazide."
- Thioacetasone
- Ethionamide.
- "Opiniazide".
Before replacing the original drug with a generic, it is recommended to consult a doctor.
Features
According to the instructions to “Ftivazidom”, it is known that when using tablets it is necessary to constantly conduct an ophthalmological examination. Together with this medicine, it is advisable to prescribe vitamins B 6 and B 1 for prophylactic purposes to prevent the occurrence of neuritis.
While taking the medication, it is not recommended to drive a car and work with other mechanisms that require increased attention.
According to the instructions to “Ftivazidom”, it is known that the shelf life is 48 months. The drug must be kept in a dark, dry place, away from children, at room temperature (plus twenty-five degrees). The cost of the drug varies from 50 to 500 rubles.
Opinions
According to reviews of Ftivazide, it is known that this is one of the most effective anti-TB drugs. It is recommended, as a rule, to patients of different ages (but not less than one year old) at different stages of the disease.
Almost everyone who used the drug says that “Ftivazid” gives a significant improvement, as well as effectively eliminates Koch’s wand, makes it stable and completely relieves shortness of breath.
The increased effectiveness of this drug is confirmed by most medical specialists. At the same time, they remind that only the attending doctor can prescribe this medication, since it is necessary to establish the optimal dosage and take into account all the prohibitions on use.
Only with the help of this approach can a good and stable result be obtained and the disease completely eliminated without causing any harm to the whole human body.