Candles "Pyrogenal" belong to immunomodulators of a wide range of effects. The drug is also available in the form of a solution for injection. The medication has the ability to activate the reticuloendothelial (connective tissue), hypothalamic-pituitary and fibrinolytic (plasmin) systems. Describing the drug "Pyrogenal", the instructions for use indicate its anti-inflammatory and desensitizing (reducing sensitivity) properties. The drug is used in adjuvant (postoperative) therapy.
Due to the ability to stimulate cells in the phagocytic system, phagocytosis, secretion of oxygen radicals, tumor necrosis factor, synthesis of interleukin-1 and interferon are activated.
Due to the effect of the Pyrogenal preparation on fibroplasts, collagen synthesis is prevented and fibrocyte maturation is accelerated.
The medication helps to activate the adrenal cortex, increases the level of hormones.
The medicine "Pyrogenal", the instructions for use recommend as a non-specific treatment for stricture of the ureters and urethra, chronic liver pathologies. The tool is used for immunorehabilitation and immunoprophylaxis against the background of incomplete recovery after an acute viral or bacterial disease. The medicine “Pyrogenal” is used in gynecology for adhesive disease, inflammatory processes in the uterine appendages. Sexually transmitted diseases, burn pathology are also referred to as indications. The injection solution is additionally used to stimulate regenerative (recovery) processes associated with diseases or damage to the nervous system (peripheral and central). Pyrogenal injections are recommended by the application for certain allergic diseases (bronchial asthma), diffuse streptoderma of chronic course, psoriasis and other pathologies.
After the injection, along with an increase in temperature (due to the pyrogenic effect of the drug), a decrease, and then an increase in the concentration of leukocytes, is noted. In addition, increased permeability of tissues, the blood-brain barrier, including.
Contraindications to the drug "Pyrogenal" instructions for use include acute fever, pregnancy, as well as individual intolerance.
As practice shows, along with a good clinical effect, good tolerability of the drug by patients is also noted. This is especially true for the use of suppositories, which, in addition, are a convenient dosage form.
Suppositories are intended for introduction only into the rectum (rectally). As a single dose, one suppository per day is recommended. The introduction is carried out on the recommendation of a doctor every or every other day. The initial dose in one dose is 50 mcg. Per day, the dosage should not be more than 200 mcg. The therapeutic course involves the introduction of twelve to fifteen suppositories.
When using Pyrogenal suppositories as monotherapy for immunorehabilitation and immunoprophylaxis, the recommended dosage is 50-100 mcg. The therapeutic course is from five to ten suppositories.
On the recommendation of a doctor, combined use of suppositories and injections of the Pyrogenal drug are allowed.
As a rule, the introduction of suppositories is not accompanied by negative effects. In some cases, it is possible to increase the temperature to 37-37.6 ° C and a slight malaise.
The drug "Pyrogenal" is compatible and quite well combined with various drugs used in the treatment of the above pathologies, enhances the effectiveness of chemotherapeutic agents during complex therapy.
Before using the medicine, it is recommended to consult a doctor.