The pharmacological effect of the hypoglycemic drug Siofor, which belongs to the biguanide group, is based on providing a clear reduction in the basal and postprandial glucose concentration in the blood. A distinctive feature of the drug is the lack of stimulation of insulin secretion, which in turn does not lead to hypoglycemia. The action of metformin is due to the following mechanisms:
- inhibition of glycogenolysis and gluconeogenesis contributes to a decrease in glucose produced by the liver;
- increased muscle sensitivity to insulin and, as a result, increased absorption of glucose at the periphery and its breakdown;
- glucose is absorbed in the intestine in a minimal amount.
Intracellular glycogen synthesis is stimulated by metformin, which has an effect on glycogen synthetase. Thus, the transport capacity of all existing and currently known transport membrane glucose proteins is increased. This is how the drug created specifically for diabetics “Siofor for weight loss” acts, reviews of which in the total mass are exceptionally positive.
The beneficial effect is on total lipid metabolism, the content of triglycerides, low density cholesterol and total cholesterol is reduced, and regardless of the effect on glucose in the blood.
Conveniently a gradual increase in the dose of the drug “Siofor for weight loss” - reviews about it are weighty evidence. Moreover, the dosage of the drug is set strictly individually, in accordance with the level of glucose in the blood, the therapy is carried out with an increase in the dosage once a week, depending on the content of glucose in the blood. However, the maximum daily intake of the drug should not exceed three tablets.
Take the drug Siofor for weight loss, reviews unanimously testify to this, it is easy: they do not chew the tablet, take it with food, and drink plenty of water. In the case when the dosage of the drug exceeds one tablet per day, the reception is divided into two to three times. Only a doctor is entitled to prescribe the duration of the treatment period with this tool.
In no case can you compensate for the missed method by taking more tablets at a time.
In order to avoid an increased risk of lactic acidosis, the dosage of the drug is significantly reduced in severe metabolic disorders.
You need to properly use the drug "Siofor for weight loss", reviews of which warn of the need to comply with the dosage prescribed by the specialist. Otherwise, the following symptoms may occur:
- loss and confusion of consciousness;
- rapid breathing;
- muscle pain;
- reflex bradyarrhythmia;
- decrease in blood pressure;
hypothermia; - pain in the abdomen;
- diarrhea;
vomiting - nausea;
- drowsiness;
- respiratory disorders;
- weakness.
In any of these cases, symptomatic therapy is carried out to eliminate the side effects caused by the overestimated dosage.
A drug that can simultaneously lower cholesterol, reduce appetite, lower blood glucose, normalize the body’s carbohydrate metabolism - Siofor 850 for weight loss. Reviews about him are entirely rainbow. This is understandable, when in some cases there is a significant loss of extra pounds, even without a diet. According to observations, weight loss varies from one to twelve kilograms per month, simply, without straining, taking the prescribed number of tablets per day.
The action of the Siofor 500 slimming drug is similar, reviews about which are similar to all reviews about the drugs of this series, regardless of the dosage, which, by the way, is 500, 850 and 1000 mg of the active substance.
The use of synthetic products in the fight against excess weight is justified only when the appointment is made by a doctor. The drug is not acceptable for alimentary obesity caused by normal overeating. In this case, the solution to the problem of excess weight will be a limited dietary diet in combination with physical exercises.