Nicotinic acid, the instructions for use of which will be discussed in this article, is a vitamin that takes part in the oxidative processes that occur in living cells, and is a drug. The medicine is presented in the form of a white powder of sour taste and odorless. It is difficult to dissolve in cold water.
It should be said that nicotinic acid (or vitamin PP) is a vitamin, antiallergic, detoxifying and hypolipedic agent that helps to improve carbohydrate metabolism, the expansion of blood vessels, including the brain, and the transfer of oxygen to tissues. She is involved in the metabolism of fats, amino acids, proteins and purines, as well as in the processes of biosynthesis.
Nicotinic acid, the instructions for which use the vitamin up to twenty-five milligrams per day, at high doses (up to four grams per day) reduces the amount of lipoproteins, triglycerides and cholesterol in the blood.
This drug is quickly absorbed from the digestive tract, and after forty minutes it turns into nicotinamide. Vitamin is metabolized in the liver, synthesized in the intestine, while excreted by the kidneys in the form of a metabolite.
Indications for use of the drug are: vitamin deficiency, parenteral nutrition, malabsorption, severe weight loss, impaired absorption of amino acids, gastrointestinal diseases, increased body need for vitamin PP, fever, hepatitis, infectious diseases that are chronic, as well as malignant tumors, pregnancy, period lactation, stress. Also, nicotinic acid, the instructions for use of which is attached to the drug, is prescribed for circulatory disorders in the brain, diseases of the vessels of the extremities, including spasms, diseases of the genitourinary system, polyneuropathy and microangiopathy.
Nicotinic acid contraindications have the following: hypersensitivity to the drug, gastric ulcer, gastritis, gout, glaucoma, hypotension, children under two years of age. Also use this medicine with caution in diseases of the facial nerves, colitis, enterocolitis, trophic and non-healing wounds for a long period of time.
Niacin side effects has the following: hyperemia of the skin, redness of the skin of the face, dryness of the mucous membranes of the eyes and skin, as well as arrhythmia, dizziness, nausea and vomiting, skin itching, myalgia, hyperglycemia, paresthesia. All these phenomena can be observed when taking large doses of the drug. If vitamin PP is used for a long time, liver dystrophy, facial skin hyperemia, asthenia, dizziness and headaches, an increase in the content of AST, alkaline phosphatase and LDH in the blood may appear.
They use the drug after meals in the following dosages: adults - twenty-five milligrams per day, children over two years old - up to twenty milligrams per day.
It should be remembered that nicotinic acid is used with caution in combination with anticoagulants and antihypertensive drugs. In any case, when used with other medicines, it is necessary to consult a specialist.
In addition, when using nicotinic acid, a balanced diet (products containing methionine) and constant monitoring of liver function are necessary. For better absorption in the digestive tract, it is recommended to drink the drug with milk.
Thus, nicotinic acid, the instructions for which were described above, is an indispensable drug in the prevention and treatment of many diseases. She takes part in metabolic and oxidative processes that occur in the body, as well as in the process of metabolism.