Accidental relationships can cause sexually transmitted ailments. For example, trichomoniasis is a common infectious disease of the genitourinary tract caused by vaginal trichomonas. Both men and women are at risk, but in the stronger sex, inflammatory trichomoniasis can occur without visible symptoms. It is important to seriously approach the solution of the problem and choose the most effective treatment. A drug like Metrogil is the best option for a speedy recovery.
Composition and purpose
The product has a uniform gel-like consistency; the color of the gel is light beige. The main component is metronidazole, it affects a large number of bacteria and protozoa (trichomonads, vaginilis gardnerella, etc.). Additional components include: propyl parahydroxybenzoate, dioxipropane, carbopol thickener, disodium salt, sodium hydroxide, distilled water.
The drug belongs to the group of antimicrobial and antiseptic agents. Metrogil is used vaginally to treat diseases such as:
- urogenital trichomoniasis;
- vulvovaginitis - inflammation of the female genital organs;
- vaginal dysbosis - pathological changes in the vagina.
Mechanism of action
As already mentioned, the main component - metronidazole - acts on many bacteria and protozoa (Trichomonas, gardnerella). Since Metrogil is administered vaginally, the active component passes through the vagina into the blood vessels of the circulatory system and begins to interact with the deoxyribonucleic acid of microorganism cells, inhibiting the processes of the compound, which leads to their death. The drug is effective in the fight against many bacteria that provoke vaginal dysbiosis.
After the first vaginal administration, the maximum concentration of the active substance in the blood plasma of a healthy woman reaches about 250 ng / ml, which is 3% of the average maximum concentration with an internal dose of a standard dose (5 g). The period for reaching the maximum concentration is from 5 to 11 hours.
And therefore, we can conclude that vaginal tablets are absorbed two times worse than Metrogil - vaginal gel. The price of the drug is quite affordable and, importantly, the quality pleases. And all because the active substances penetrate the vaginal secretion faster, so the effectiveness of the gel does not decrease even at low concentrations of the main substance.
Application and dosage
The standard dose for single administration is 5 g (fully filled applicator), for use twice a day (morning and evening). Since Metrogil is administered vaginally, its use consists of the following items:
- remove the applicator from the wrapper;
- open the cap on the tube and put on the applicator;
- hold the tube so that the nozzle is in a vertical position (hole up), and squeeze the product from the package. It is necessary to ensure that the contents fill the applicator;
- unscrew the filled applicator and close the tube with a cap;
- after the applicator is inserted into the vagina, slowly press on the piston pin and completely squeeze out the contents;
- After removing the applicator, it must be treated with ethanol. Then it should be put in the packaging, where it will be stored until next use.
It is in this order that Metrogil (vaginal gel) should be used, the instructions for which are in the package.
It is necessary to clearly follow the course of treatment, which lasts about 6 days. During this period it is forbidden to live sexually.
Side effects
The concentration of the active substance of the drug is high, it is quickly absorbed into the blood vessels and passes the body's protective barriers. The use of this drug has its consequences. "Metrogil" vaginal, the instruction of which states that the gel should be used in the specified dosage, has a number of side effects:
- Genitourinary system - a fungal infection (thrush), inflammation of the vaginal mucosa (colpitis), unpleasant sensations of itching, vaginal (non-fungal) discharge, swelling of the labia, frequent urination.
- Gastrointestinal tract - a taste of metal, nausea, loss of appetite, cramps in the abdomen or uterus, impaired bowel function (diarrhea or constipation).
- Central nervous system - often dizzy, migraines.
- Hematopoietic organs - impaired hematopoiesis, a decrease in the level of leukocytes (hypoleukocytosis) or an increase in the level of white blood cells.
- Allergic phenomena - skin rash, itching.
It is important to strictly apply Metrogil (vaginal gel) according to the rules. Reviews say that this drug is already quite effective, and therefore do not need to exceed the indicated dosage (full applicator).
Contraindications
Metronidazole (the active substance of the gel) quickly enters the bloodstream and in some cases can be dangerous. The risk group includes people who have increased sensitivity or individual intolerance to the main or additional substance of the drug. And therefore, like any medicine, Metrogil (vaginal gel) has a number of contraindications. Reviews say that the drug can not be used in such cases:
- in case of disorders of the central nervous system: reflex convulsions, neurological diseases with convulsive attacks, disorder of coordination of movements ;
- with a reduced number of white blood cells in the blood (hypoleukocetosis);
- with increased sensitivity of the body to the active substance of the gel;
- if there is a violation of the liver;
- with lactation or in the first trimester of pregnancy.
It is important to use Metrogil vaginal very carefully during pregnancy. Reviews of doctors indicate that the drug can be used after the first trimester, but only after agreeing everything with your doctor. During lactation, you can use the gel, but during the course of treatment (6 days), you need to stop feeding, since the active substance has a bad effect on the condition of the child.
The use of Metrogil with other drugs
As already mentioned, Metrogil is administered vaginally, you need to combine it with other medicines very carefully and only after consulting with your doctor.
For example, an anticoagulant such as Warfarin, intended for the treatment of thrombosis, is undesirable to use together with Metrogil. And all because the active substance (metronidazole) slows down blood coagulation.
The sensitizing drug Disulfiram, which is used to treat relapses of chronic alcoholism, is also undesirable to combine with a vaginal gel, since there is a risk of developing neurological syndromes that can affect certain structures of the nervous system. Patients who took Disulfiram can use Metrogil after two and a half weeks.
The synthetic drug “Cimetidine” inhibits the metabolism of the active component of “Metrogil”, which can provoke an increase in its concentration in blood plasma and thereby cause negative side effects.
Reviews and cost
It will help to cure diseases of the urogenital tract "Metrogil" vaginal, patient reviews suggest that this drug has many advantages:
- The tool is very easy to inject using a special plastic syringe. Moreover, this procedure does not cause discomfort.
- Due to the thick consistency, the drug does not leak and does not stain clothes.
- The period of use of the drug is about 6 days. And this means that the gel is quite effective, as it eliminates the problem in a short period of time.
Another huge plus of the drug is its low cost: a gel tube, depending on the volume, costs from 85 to 200 rubles. In addition, patients note such qualities as an excellent disinfectant and antimicrobial effect.
"Metrogil" is a fairly popular drug, therefore, its effect is heard differently. Among its shortcomings, one can distinguish the repetition of a typical form of the disease after recovery. But this fact can be explained by the fact that often women prefer underwear (thong), which provokes the resumption of the disease.
Another reason for the relapse of vaginitis is a violation of the vaginal microflora, which must be restored after treatment. Imbalance of bacteria provokes the re-development of opportunistic flora.
Similar drugs
There are many drugs that have a similar healing effect. Like Metrogil's vaginal, the price of some of them is low. Similar drugs include: Gravagin, Trichopolum, Mikozhinaks, Metroksan, Metromikon, Neo-penotran, etc. All these drugs have metronidazole in their composition and are intended for the treatment of similar diseases.
They are available in various forms: internal tablets, suppositories, vaginal tablets and suppositories. They may also differ in additional substances in the composition. Therefore, self-replacement of the drug is unacceptable, all issues must be agreed with the doctor.
"Metrogil" is the choice of most women, since this gel is very effective in combating the causative agents of trichomoniasis.
Recommendations of doctors
Trichomoniasis is transmitted sexually, the disease can be quickly cured, but for this you need to strictly follow the rules. Only in this case, the treatment will be effective and Trichomonas completely die.
Advice:
- Both partners must undergo treatment, otherwise it will not be effective. This rule applies even if the causative agents of trichomoniasis are not found in one of the partners. Moreover, Metrogil - a vaginal gel, the price of which is quite low - will delight you with a quick result.
- This disease is often accompanied by other sexual ailments, and therefore it is necessary to carry out complex treatment.
- After trichomoniasis, immunity to trichomonads does not appear, there is always a risk of re-infection. It is necessary to carry out prevention and restore the vaginal microflora.
- It is important to clearly follow the rules of use and in no case to violate the dosage.
- During treatment, it is strictly forbidden to live sexually.
- Self-medication is a way to aggravate the problem, all medications should be prescribed by a doctor. This also applies to the replacement of drugs.
- During treatment, you can not drink alcoholic beverages, as this threatens with unpleasant consequences.
But the most important point is the availability of a permanent healthy partner for sexual intercourse. In other cases, you must not forget about the use of condoms, which can protect against trichomoniasis. You can also use chlorhexidine (disinfectant solution). But this tool is not very reliable, to be sure you need to be examined by a doctor.
However, if the disease is still found, you should not be upset. "Metrogil" - a vaginal cream - will help to cure trichomoniasis successfully and quickly enough. This tool has been tried by many women who talk about its effectiveness in thematic forums. It is important to clearly follow the instructions, not to violate the dosage, and very soon the disease will recede.