The drug "Xanthinol nicotinate" belongs to the group of vasodilators. It is used in medicine in the treatment of various vascular pathologies. The medicine is available in the form of a solution intended for administration intravenously and intramuscularly, and in the form of tablets. Glass ampoules with a solution contain 0.2 milliliters of the drug. They are in a blister pack of five pieces or in a cardboard box of ten pieces.
What is the composition of “Xanthinol nicotinate”?
The drug in the form of tablets is in contour bezjacheykovyh packages (ten pieces). Each box contains two records. The drug has the following composition: the active component is xanthinol nicotinate (150 milligrams in one ampoule and tablet). Excipients - corn starch, calcium stearate (aqueous), povidone, milk sugar.
The scope of this drug
The drug "Xanthinol nicotinate" is used in many medical fields, it has the following indications for use:
- thromboangiitis with obliterans type - Buerger's disease;
- Raynaud's disease;
- atherosclerosis of the vessels of the legs with obliterating course;
- in the treatment of retinopathy;
- migraine;
- scleroderma;
- Meniere's syndrome;
- in the treatment of acute forms of superficial thrombophlebitis;
- with the appearance of pressure sores;
- during the treatment of angiopathy in diabetes;
- scleredema Bushke;
- cerebrovascular insufficiency;
- with pathologies of blood circulation of the brain of the head;
- atherosclerosis of the brain of the head;
- excessive cholesterol;
- hypertriglyceridemia;
- coronary arteriosclerosis of arteries;
- intrauterine and postpartum asphyxia of the fetus;
- dermatosis that appeared with vascular trophic disorders.
When is the drug not recommended?
"Xanthinol nicotinate" is forbidden to take in the following conditions:
- glaucoma;
- arterial hypotension;
- severe defects in the functioning of the kidneys;
- acute stage of gastric ulcer;
- with mitral stenosis;
- individual intolerance or allergy to the active substance of the drug;
- chronic heart failure in acute and decompensated form;
- acute myocardial infarction;
- first trimester of pregnancy;
- breast-feeding.
The drug is used orally (tablets) and injection - both inside the vein and inside the muscle.
Taking tablets of this medicine
Xanthinol nicotinate tablets are taken orally. They are undesirable to grind, knead, chew or break, they are swallowed whole and washed down with water in a small amount. For a day, you should take the drug three times, 150 milligrams. In especially serious cases, a single dosage of the drug increases to 300-600 milligrams. In the presence of positive dynamics, this dosage is gradually reduced. The therapeutic course is two months.
Features of the use of the solution
"Xanthinol nicotinate" in injections is administered intramuscularly in the form of a solution (concentration - 15%) of 2-6 milliliters per day. The therapeutic course varies from two to three weeks. The drug is used intravenously by a jet method 1-2 times a day, two milliliters each (solution also at a concentration of 15%). During drug administration, the patient should be put on the couch. The duration of treatment ranges from five to ten days. In addition, the drug can be administered by drip intravenous injection.
For this purpose, ten milliliters of a solution should be diluted in a concentration of 15% in a 0.9% solution of hydrochloride (200 ml) or in dextrose (200-500 ml, 5%). Through the drip method, the drug is administered per minute for 40-50 drops. If there are acute defects in tissue blood supply, then along with the injection, a drug in the form of tablets is prescribed. The drug is taken three times a day for three hundred milligrams.
Reviews about "Xanthinol Nicotinate" are available in large numbers.
Overdose and side effects
If the medicine is used in large doses for a long time, then this can cause hyperuricemia, changes in glucose tolerance, and an increase in the degree of liver enzymes. During an overdose, the following symptoms are observed: abdominal pain, vomiting, decreased blood pressure. In this case, treatment is symptomatic. When taking a drug, sometimes such side effects may occur:
- malfunctions of the vascular system and the heart - a decrease in blood pressure, a rolling feeling of warmth throughout the body, redness on the skin;
- digestive system disorders: anorexia, diarrhea, gastralgia, nausea, with prolonged use, an increase in the degree of alkaline phosphatase and transaminases may be noted;
- malfunctions of the nervous system - dizziness and weakness.
Special instructions for the use of the medication
When using Xantinol Nicotinate tablets, some significant conditions must be observed:
- with caution should be taken with arterial labile pressure;
- very carefully you need to use the drug along with antihypertensive drugs;
- pregnant women should take the drug in the middle and late pregnancy under the strict supervision of a specialist;
- if you take large doses of the drug, it is possible to lower blood pressure, as well as dizziness;
- it is desirable that the drug in the form of a solution does not enter the eyes and mucous membranes;
- with caution should be taken to patients who drive a car, and patients whose activities are associated with any hazardous production and require high concentration.
Analogues of this drug
Among the most common analogues of "Xanthinol nicotinate" are the following drugs that differ in the identical therapeutic effect:
- "Theodibaverine";
- "Teoverin";
- "Theobromine";
- Vincanor
- The Teminal.
Preparations with the same substance as the active ingredient are as follows:
- Complamex;
- "Sadamin";
- "Vedrin";
- Xavin
- "Angioamine";
- Theonikol;
- "Sadamin";
- "Megemin".
Reviews on "Xanthinol Nicotinate"
The very first thing you can pay attention to when reading patient reviews about this drug is complaints about the lack of a pill in pharmacies. But injections are always available. That is why people often ask questions: is it possible to replace tablets with a solution, how to calculate the dosage or replace a drug that is not on sale? A qualified specialist prescribing treatment should answer them.
Patients most often respond to the use of injections positively. For example, in patients with multiple sclerosis, after using them, numbness in the legs and arms goes away, and the condition improves. There is also an opinion that with arthrosis, a remedy should be taken along with chondroprotectors in order to improve joint blood supply and the delivery of nutritional components to them.
The drug "Xanthinol nicotinate" is effective and can be successfully used in the complex treatment of various diseases, if you need to improve your blood circulation.
Among the shortcomings are the following: quite a few contraindications, side effects, lack of pills on sale, unpleasant feeling after injection, over time - nausea and abdominal pain, increased blood sugar and a negative effect on the liver.
We reviewed the instructions for use with Xanthinol Nicotinate, analogues and reviews.