A drug called Mardil Zinc Max is a fifty percent aqueous solution of chlorpropionic acid and zinc chlorpropionate. In the framework of external and local application on the affected skin areas or mucous membrane, the drug is able to interrupt growth with the vital activity of pathologically altered cells and tissue.
About the medicine
The presented drug “Mardil Zinc Max” acts on the body through dehydration, anticoagulation and devitalization. When used on the affected areas, the drug leads to fixation, followed by mummification of pathologically altered tissues with which the agent comes into contact. The direct effect of this drug can be expressed in discoloration of the cover and mucous membrane with the appearance of a gray characteristic shade.
Subsequently, devitalized pathological tissues dry out and change color to a brown tint. This is due to mummification. Mummified scabs can spontaneously separate only after absolute re-epithelization in two to three weeks. Healing occurs, as a rule, without any complications, especially in the absence of secondary infections, without leaving significant scarring and scars, and, in addition, deformations of the adjacent tissue or impaired organ functions.
Composition and format of the issue
Mardil Zinc Max is available in topical form. The drug is a fifty percent aqueous solution of chlorpropionic acid and zinc chloropropionate. 1 milliliter contains 0.5 milliliters of zinc. The product is placed in dark glass vials. Five glass microcapillaries with a foam container are supplied. The medicine is packaged in a cardboard box.
Pharmacokinetics
It is worth noting that when applied to the affected area of the skin or mucous membrane, the drug “Mardil Zinc Max”, as a rule, is not absorbed. It does not have any systemic effect on the human body.
Indications
"Mardil Zinc Max" is prescribed for the treatment of lesions of the skin and mucous membranes with the following pathologies:
- Against the background of vulgar and anogenital warts.
- In case of a plantar wart.
- When flat growths occur.
- With acrochordons (skin horn).
- Against the background of seborrheic keratoma and seboroids.
- In the event of benign nevi. For example, with low-pigment, non-pigment, papillomatous, fibroepithelial nevus, tested for benignity.
Dosage regimen for external use
As indicated by the instructions for "Mardil Zinc Max", the therapy process is carried out on an outpatient basis under the strict supervision of a doctor. The treatment procedure does not require any anesthesia. The drug is applied with a plastic spatula, either by means of a cotton swab or by means of a capillary onto the surface of the neoplasm previously defatted with seventy percent alcohol. Processing is carried out for one to three applications before whitish gray staining.
Tissue discoloration occurs within two to three minutes, almost immediately after application. In the case of severe hyperkeratosis within five to seven minutes. At the same time, a change in the consistency of the neoplasm into a dense structure can occur. The dosage of the drug directly depends on the type, size, density and nature of the severity of hyperkeratosis and may be 0.2 milliliters. This is the maximum daily dosage.
The number of treatment sessions, as a rule, varies from one (with flat warts) to three to four (against the background of plantar growths). Treatment is carried out until the pathological element completely disappears with intervals between sessions of at least twenty-four hours. Around the formation after application of the drug, a transient strip of hyperemia and edema is observed, which disappears without a trace twenty-five to forty minutes after the completion of the procedure.
As a rule, no additional therapeutic measures after application of this drug are required. The next day after treatment, pathological foci mummify, acquiring a dark or brown shade, sharply decreasing in size. Mummified scabs can be separated only after complete epithelization, usually this happens spontaneously after three weeks. Healing is carried out without any complications, especially in the absence of secondary infections, without leaving significant scarring, scars and deformation of adjacent tissue or organ dysfunction.
When applied topically
According to the instructions for “Mardil Zinc Max”, treatment for anogenital warts is carried out on an outpatient basis under the supervision of a doctor, this procedure will not require anesthesia. The drug is applied with a universal probe or with an applicator. After applying the product, the color of the fabric changes to whitish staining. The amount of medication applied directly depends on the size of the neoplasm and the area of damage and can range from 0.02 to 0.2 milliliters. During each procedure, no more than two to three lesions are treated with an area of up to three square centimeters.
The maximum daily dosage in the framework of local application of the described drug, as in the previous case, is 0.2 milliliters. In the case of a more extensive lesion, drug therapy should be carried out in several stages with an interval of one day. When applying the drug, a slight swelling of the mucosa may occur.
Within three days after the use of the medication, rejection of necrotic tissue occurs. Complete regeneration is observed for ten to fourteen days. With the appearance of large anogenital warts in case of incomplete necrotization, repeated application of the therapeutic agent is allowed after five to seven days. Next, let's talk about adverse reactions.
Side effect
In accordance with the instructions, the use of Mardil Zinc Max in rare cases can lead to a change in skin pigmentation and the formation of superficial scars. Given the normal course of the epithelialization process and the complete absence of secondary infection, and, in addition, the independent separation of mummified scabs, the likelihood of such negative consequences is very small. Swelling of the tissue can be observed, although very rarely, and in the case of individual sensitivity to the ingredients of the drug, various allergic reactions in the form of skin itching are possible.
Contraindications
It is forbidden to use the described medication in a number of the following cases:
- With malignant neoplasms of the skin and mucous membrane.
- In the case of a pronounced tendency to form keloids.
- During pregnancy, as well as during lactation.
- Age to eighteen.
- The appearance of hypersensitivity to the ingredients of the drug.
During pregnancy
Any studies related to the study of the possible effects of this medication on the body of pregnant women and nursing mothers have not been conducted to date. Treatment in this group of patients should be prescribed only in cases where the benefit of the medication in question for the mother exceeds the possible risks for the child.
Analogs “Mardil Zinc Max” should be selected by a doctor.
special instructions
Before opening the medicine, the vial must be shaken and the solution, which will fall into the upper part of the vessel, should be moved to its bottom. The opened cone must be in a strict upright position. The described medication contains acid in its composition. Avoid getting this medication on a healthy skin surface or mucous membrane. If the medicine accidentally enters the healthy skin or mucous membrane, then it is necessary to remove the agent as soon as possible with a tampon moistened with water.
When treating the affected areas of the skin that are located next to the eye area, special precautions must be taken. Therefore, it is very important to avoid getting this medication in your eyes. In the event that the medication accidentally enters the visual organs, it is urgently necessary to rinse them with a large volume of water and a one percent solution of sodium bicarbonate, and then consult a doctor. You can not remove the mummified scab by scraping or using a mechanical tool. The scab should be separated independently from a healthy skin or mucous membrane, otherwise a violation of the healing process of the tissue and the formation of scars is not excluded.
Until the absolute healing of the skin or mucous membrane is achieved, it is not recommended to swim in the pool and in the open water, and you should also try to avoid the action of direct sunlight and ultraviolet radiation. On the day of therapy, it is recommended to limit any water procedures. It is advisable to try to avoid injuries and contamination of the treated pathological foci before the process of complete epithelization. Before you discard the bottle, you should wash off the remnants of this drug under running water. The empty bottle should be thrown into the garbage container.
Overdose and drug interactions
With improper use of the drug, the formation of erosion is likely. In order to prevent acid burns, this medication needs to be washed off under running water. Healing can be carried out independently without the use of additional drugs or with the use of wound healing agents.
The interaction of the considered medicinal product with other external medications has not been established.
Cost
What is the price of Mardil Zinc Max?
In pharmacies, the described therapeutic agent can currently be purchased for 1200 rubles. But this medicine can be ordered two hundred rubles cheaper on the website.
Analogs "Mardil Zinc Max"
Currently, there are no structural analogues of this tool. Thus, with the same active component of substitutes, this medicine does not yet exist. In this regard, it is necessary to contact the attending physician with a request for the selection of a replacement medicine, which will have similar properties, but with a different active substance.
Reviews about "Mardil Zinc Max"
Despite the rather high cost, people on the Internet often praise this medicine in their reviews. For example, it is noted that the drug in question helps well in case of a plantar wart, with the appearance of flat growths, and, in addition, helps patients with acrochordones or against the background of seborrheic keratoma and seboroids. On the side effects in the reviews of "Mardil Zinc Max" complaints, as a rule, do not occur.