The drug "Tarceva", or rather, its main active ingredient - erlotinib - is a powerful tyrosine kinase inhibitor. This enzyme is present in the HER1 / EGFR epidermal growth factor receptor, and its blocking helps to delay the growth of a malignant tumor.
According to recent studies, the use of Tarceva extended the life of patients with metastatic lung cancer by almost 42%. In addition, the drug reduces the manifestation of the symptoms associated with this pathology - cough, pain and shortness of breath.
The drug is dispensed only as prescribed by the doctor. It can be purchased at the pharmacy chain, but it is expensive. And the “Tarceva” generics are Erlonat and Erlocip, licensed by renowned Indian companies Natco Pharna Ltd. and Cipla Ltd., are much cheaper.
Where can the drug "Tarceva" buy cheaper
In Russia, Tarceva generics from well-known Indian manufacturers can be purchased on the special website of a large Indian company with a 5-year reputation . The condition for the provision of services is the availability of relevant documents that can confirm the need for modern treatment.
The price of generic “Tarcev” tablets is not reduced due to the fact that these drugs are inferior to the brand ones. They are produced under an official license and under strict quality control. Indian corporations simply do not have to invest in technology and research. And this in the end is able to help out an ordinary buyer who has fallen into a difficult everyday situation. Therefore, when ordering generic drugs on this site, do not be afraid that you get a fake!
Dosage and dosage
The drug is taken orally, an hour before or 2 hours after a meal, once a day.
Depending on the diagnosis, the dosage of Tarceva varies:
- in case of non-small cell lung cancer - 150 mg (at one time);
- if pancreatic cancer is detected, 100 mg is prescribed, in combination with a drug containing gemcitabine.
If necessary, the dose is reduced gradually, by 50 mg.
When symptoms of pathology progression appear, treatment with Tarceva should be discontinued.
Erlotinib ("Tarceva") in a dose exceeding the recommended one can cause skin rashes, diarrhea in the patient and lead to an increase in the level of liver enzymes. These manifestations require symptomatic therapy, and treatment with Tarceva is suspended for this time.
Contraindications
This tool is not prescribed for the detection of severe allergies to erlotinib. "Tarceva" is also not indicated for pregnant and breastfeeding.
Specialists should be careful when prescribing the drug for impaired liver function, as well as for patients under the age of 18.
Side effects
During the use of Tarceva tablets or generics, the following undesirable effects may occur in patients:
- diarrhea;
- nausea and vomiting;
- anorexia;
- epigastric pain;
- gastric bleeding (especially in the case of the simultaneous use of the drug "Warfarin" or NSAIDs);
- conjunctivitis;
- keratitis;
- nosebleeds;
- coughing and shortness of breath;
- headache;
- neuropathy
- dry skin, itching;
- weight loss.
Application features
With the progression of signs of pulmonary pathology (cough, shortness of breath and fever), the drug Tarceva is stopped taking until the cause is clarified.
Patients at risk of dehydration need to control the amount of electrolytes in the blood (including potassium), as well as monitoring the functioning of the kidneys.
Since therapy with Tarceva in some cases led to the development of liver failure, liver function should be monitored throughout the course, especially in those patients who have pathologies or receive hepatotoxic drugs. In case of detection of severe liver damage, the use of Tarceva is stopped.
The use of the drug is also impossible in case of detection of gastrointestinal perforation, with the development of exfoliative or bullous skin lesions, as well as with the occurrence of pain in the eyes or exacerbation of ophthalmic pathological processes.
During the treatment process and at least 14 days after it, women need reliable contraceptives.