The drug "Bisoprolol-Prana" is a 10-milligram tablets, which are coated with a food coating. One tablet of this drug contains 5 mg of bisoprolol fumarate, which is the main active ingredient.
In addition to it, as auxiliary, the drug contains primellose, povidone, starch, aerosil, talc, microcrystalline cellulose, magnesium stearate. The components of the tablet shell are polyvinyl alcohol, titanium dioxide, dye iron oxide, talc, macrogol.
It is sold in packs of 30 tablets.
The pharmacological effect of the drug "Bisoprolol" application instructions describes in this way. This medicine has properties that provide its antianginal, antiarrhythmic, as well as effective hypotensive effect. Therefore, the main indications for its appointment are diseases such as arterial hypertension, various types of arrhythmias, angina pectoris. It is used as an effective therapeutic drug for the treatment and prevention of moderate heart failure in the post-infarction period.
Contraindications to the use of the drug are the patient’s hypersensitivity to the components of the drug, diagnosed sinus bradycardia, cardiogenic shock, severe cardiac and respiratory failure. The use of the drug during pregnancy and during the lactation period should be commensurate with the degree of possibility of the risks associated with its use. Otherwise, it can pose a threat to the development of the fetus or unborn child. If a woman took the medicine less than two to three days before giving birth, it is necessary to conduct special medical monitoring of the baby's condition.
The drug "Bisoprolol" instructions for use recommend taking without chewing, usually in the morning before meals or during the morning meal, drink tablets with a small amount of water. The daily dose of a single dose of the drug is 1.25-10 milligrams. If necessary, an increase in dose is allowed, but only with constant monitoring of the pulse and pressure of the patient.
Depending on the nature of the disease, the dose of taking the medicine varies. So, with arterial hypertension, it is 5-10 mg, 1.25 mg - with chronic failure. Treatment is carried out for seven days. With normal drug tolerance, treatment is continued according to the scheme, which is described in detail in the instructions for use of the drug. However, it should be borne in mind that the maximum dose of the drug per day cannot exceed 20 milligrams.
The drug "Bisoprolol" instructions for use indicate the following possible side effects. It should be borne in mind that their manifestation, as set out in the instructions, applies only to those cases when the dose of the drug did not exceed 40 milligrams.
Side effects are observed on the part of various body systems, for example, on the part of the nervous system it is dizziness, depression, anxiety, less often - hallucinations and thinking disorders, visual disturbances.
From the gastrointestinal tract, the most common symptoms are diarrhea, nausea, various dyspeptic symptoms. Rash, allergic reactions on the skin, dermatitis are possible. In the treatment with the drug "Bisoprolol" instructions for use indicate the possibility of headaches and pains in the epistragal region, involuntary weight gain.
Drug interaction of the drug is characterized as follows. If you take the medicine "Bisoprolol" along with amiodarone, verapamil, alpha methyldopa, quinidine drugs, then there is a risk of impaired automatism, and cardiac contractility increases. Incompatible drug with MAO inhibitors.
In case of an overdose, it is recommended to do a gastric lavage, administer to the patient adsorbing drugs (atropine), sedatives and cardiotonic drugs (epinephrine, diazepam, lorazepam, etc.), as well as cardiac glycosides. In the event of a heart block, transvenous stimulation is urgently needed.