Sometimes situations arise when it is necessary to quickly stop an attack of pain, whether it be a headache or a toothache. In this case, special preparations are used. One of them is “Ketanov”, positioned by the instructions as an effective and effective medicine. Its action is aimed at getting rid of soreness, as well as relieving inflammation. Indications and contraindications for taking "Ketanova" will be presented in this article.
Description and release forms
The drug is included in the group of non-steroidal anti-inflammatory drugs or NSAIDs. The main actions of the drug are anesthesia and removal of inflammation. The main active ingredient of Ketanov is ketorolac, which is considered to be a derivative of pyrrolysin-carboxylic acid. There are two forms in which the drug is produced:
1. The tablet form. It is represented by round, white colored tablets in a shell.
2. The solution for administration intramuscularly. It can be completely transparent or have a pale yellow tint.
There is no Ketanov ointment. Contraindications and instructions for use, we will describe for tablets and injections. With such an active substance, Ketonal ointment is commercially available.
The tablets contain 10 mg of ketorolac, while the concentration of the active substance in injections reaches 30 mg per 1 ml.
In addition to ketorolac, the composition of the drug also includes auxiliary components that increase the effectiveness of the main active substance. This in turn makes it possible to quickly and efficiently relieve pain and stop the process of inflammation.
Contraindications to "Ketanov" we consider below.
Drug action
The drug analgesic action has a pronounced anti-inflammatory and analgesic effect. Also, the drug has a slight antipyretic effect. The active substance inhibits COX enzymes of all types, while affecting the synthesis of arachidonic acid and inhibiting the production of prostaglandins, which provoke inflammatory processes.
Benefits Compared to Other Medicines
Ketanov has several advantages over other similar drugs. These include:
1. The drug does not affect the number of platelets in the blood and their activity.
2. Does not impair respiratory function.
3. Does not affect the psychomotor functions of the body.
4. Not addictive and addictive.
5. Does not inhibit the nervous system.
Tablets "Ketanov" indications for use are quite extensive.
Thus, the drug is especially effective as an anti-inflammatory and analgesic that can cope with pain of any intensity and degree. It is more effective than other drugs in the NSAID group. In terms of the effect on pain, the properties of Ketanov are comparable with the action of morphine.
The drug completely relieves pain within half an hour after taking the medication, while the maximum effectiveness occurs after two hours. If Ketanov is taken orally, it is rapidly absorbed from the gastrointestinal tract, but the presence of fatty foods in the contents of the stomach can prolong this process. In this case, the maximum concentration of the active substance in the blood is observed one hour after administration.
If the drug is administered intramuscularly, then the maximum concentration is reached after half an hour. Studies have shown that ketorolac is able to penetrate the placental barrier, as well as into breast milk during lactation. Therefore, its purpose during pregnancy and during breastfeeding is contraindicated.
The drug is completely excreted from the body by the liver and kidneys. The elimination half-life takes approximately 5-6 hours. However, in the elderly and in patients with kidney pathologies, this period may be longer. The liver condition does not affect the half-life of the drug.
Before considering the contraindications to the use of Ketanov, we will describe in what cases it is prescribed.
Indications for use of tablets
The drug in the form of tablets is prescribed to relieve pain and inflammation in the following cases:
1. Toothache of any genesis.
2. The inflammatory process in the gums, including flux.
3. Colic in the liver or kidneys.
4. Otitis and inflammatory processes in the middle ear.
5. Osteoarthritis.
6. To relieve symptoms of gout and radiculitis.
7. Anesthesia for cancer.
8. Gynecological pain.
9. Sinusitis in any form.
These indications must be strictly observed.
Injections and indications for them
"Ketanov" for intramuscular administration is prescribed less frequently. In general, injections are prescribed for pain and inflammation of a high degree of intensity. As a rule, specialists prescribe such injections during the rehabilitation period after the operation in the following medical areas:
1. Surgery (general, emergency and purulent).
2. Gynecology.
3. Dentistry.
4. Orthopedics.
5. Otolaryngology.
6. Urology.
7. Traumatology.
Ketanov is also prescribed as part of complex therapy for sports and domestic injuries, as well as bruises and sprains.
Contraindications to the use of a medication
Any drug from the NSAID group has a number of contraindications, and Ketanov is no exception. So, the drug can not be taken with the following diseases:
1. Intolerance to the components that make up the drug.
2. Individual reaction to acetylsalicylic acid.
3. Predisposition to bronchospasm, asthma and angioedema.
4. Dehydration and hypovolemia.
5. Erosion on the mucous membranes of the intestines and stomach.
6. An ulcer of the stomach and duodenum.
7. Hemophilia, bleeding disorders, a tendency to develop peptic ulcers.
8. Stroke hemorrhagic appearance.
9. Hemorrhagic diathesis.
10. The period of pregnancy and lactation.
11. Age under 16 years.
In case of violations in the functioning of the kidneys and liver, heart failure in a chronic form, as well as hypertension, the drug is taken with extreme caution and only strictly at the dosage indicated by a specialist. These conditions also relate to contraindications to Ketanov.
Use caution with the drug.
The attending physician at his discretion prescribes a remedy for the following diseases:
1. Cholecystitis.
2. Systemic lupus erythematosus.
3. Bleeding and ulcers in the gastrointestinal tract in the patient's history.
4. The presence of polyps on the mucous membrane of the nose and nasopharynx.
5. Cholestasis.
6. Arterial hypertension.
7. Sepsis.
8. The age of the patient is over 65 years.
9. Hepatitis of all types.
You can not take it at the same time with other drugs from the NSAID group. This increases the risk of bleeding and may aggravate the patient's condition. Due to the effect of ketorolac on blood coagulation, it can not be taken before surgery. Contraindications to Ketanova injections are similar.
Side effects of the drug
Most often, against the background of taking the drug, the following adverse reactions develop:
1. Severe diarrhea.
2. Swelling of the lower extremities and face.
3. Nervousness, irritability and anxiety.
4. Violation of coordination of movements.
5. Dizziness, appearing paroxysmally.
6. Lethargy and drowsiness.
7. Allergic reactions.
8. Shortness of breath and shortness of breath.
9. Heartburn and nausea.
Reception "Ketanov" is able to provoke side effects from all organs and systems of the body, including cardiovascular, hematopoietic, digestive and respiratory.
An allergic reaction to the drug can be of varying degrees of intensity up to anaphylactic shock and Quincke's edema. Such reactions, although rare, can have very serious consequences for the body, so an ambulance should be called at the first sign.
Exceeding the dosage prescribed by a specialist can lead to pain in the abdomen, nausea, vomiting, impaired renal function, gastritis and ulcers.
The article examined the contraindications and side effects of Ketanov.