Surely everyone knows such a drug as "Analgin." The composition of the drug, its release form and features are presented below. Also in the materials of this article you will find detailed instructions for the use of the medication in question.
Forms of release of the drug and their composition
What does a medication like Analgin contain? The composition of the mentioned funds depends on its release form. The most popular among patients are two forms of the drug in question. Let's consider them in more detail.
- The composition of "Analgin" in tablets is as follows: as an active ingredient, this medicine contains metamizole sodium. As for the auxiliary components, they are presented in the form of potato starch, sugar, calcium stearate and talc.
The drug in the form of tablets has a white or slightly yellowish color, as well as risk, chamfer, flat-cylindrical shape and a bitter taste. On sale, the agent in question comes in cell or non-cell packaging.
- The composition of “Analgin” in ampoules is as follows: the drug contains metamizole sodium as the main substance, and water for injection as an auxiliary substance.
This tool is a transparent yellowish liquid, which is contained in ampoules and boxes of paper, respectively.
Pharmacology
The drug "Analgin", the composition of which was presented above, is a non-steroidal anti-inflammatory drug, as well as a pyrazolone derivative. By its mechanism of action, this medicine is practically no different from other NSAIDs. It is capable of non-selective blocking of COX and reduce the formation of prostaglandins from arachidonic acid.
This medication prevents the conduct of proprio- and extra-receptive, as well as pain impulses along the bundles of Burdach and Gaulle. It increases heat transfer and increases the threshold of excitability of centers (thalamic) pain sensitivity.
A distinctive feature of this tool is a slight severity of the anti-inflammatory effect, which causes a weak effect on the gastrointestinal mucosa and water-salt metabolism.
What other properties are inherent in the drug "Analgin"? The composition of this medication is such that it has an antipyretic, analgesic and even slight antispasmodic effect, including with respect to the smooth muscles of the biliary and urinary tract.
Indications for taking pills
Such a drug is used for pain of various origins, namely when:
- renal and biliary colic (in combination with antispasmodics);
- headache;
- myalgia;
- postoperative pain;
- neuralgia;
- Toothache
- algodismenorea;
- migraine pain;
- febrile conditions, which are manifested in infectious and inflammatory diseases.
Indications for use of injection
This form of the drug is also used to eliminate febrile syndrome (including for infectious and inflammatory diseases, bites of insects such as mosquitoes, gadflies, bees, post-transfusion complications).
In addition, an injection of analgin is prescribed for pain syndromes of moderate and weak severity:
- neuralgia, arthralgia, myalgia, decompression sickness, biliary colic;
- herpes zoster, renal colic, burns;
- intestinal colic, headache, injuries;
- orchitis, myositis, radiculitis, postoperative pain;
- toothache, algodismenorea and others.
Contraindications
The drug in tablets is not prescribed for:
- bronchial asthma;
- hypersensitivity;
- "Aspirin asthma";
- bronchospasm;
- oppression of blood;
- blood diseases and stuff.
As for the solution, it is not used in the first three months of life, with diseases of the kidneys, anemia, leukopenia, pregnancy, etc.
Method of using tablets
How should I use Analgin tablets (their composition was presented above)? This drug is prescribed orally in the amount of one piece twice a day after a meal. The maximum single dose is 1 g, and the daily dosage is 3 g.
When using the medicine (more than one week), constant monitoring of the working condition of the liver and the picture of peripheral blood is necessary.
For children, this drug is prescribed 5-10 mg per kg of body weight three times a day for no more than three consecutive days (the tablet is pre-crushed).
The medicine in question cannot be used as an antipyretic for more than three days, and as an anesthetic for more than 5 days.
Method of using the solution
Alcohol, "Analgin", iodine (the composition of these funds can be found in the instructions) - should always be present in the home medicine cabinet.
The drug in question in ampoules is administered intravenously or intramuscularly with very severe pain.
For adult patients, this drug is recommended to use 250-500 mg three times a day. The maximum single dosage is 1 g, and the daily dosage is 2 g.
For children, this drug is prescribed at a rate of 5-10 mg per kg of body weight twice a day. For babies up to one year old, the drug is administered intramuscularly, for no more than three consecutive days.
The injected solution should have the same temperature as the patient's body.
Dosages over 1 g must be administered intravenously.
Side effects
The drug "Analgin" can cause:
- impaired renal function, oliguria, proteinuria, anuria, interstitial nephritis;
- agranulocytosis, red staining of urine, leukopenia, Quincke's edema, thrombocytopenia;
- allergic reactions, malignant exudative erythema, bronchospastic syndrome, decreased blood pressure;
- infiltrates at the injection site.