"Enterofuril": side effects, purpose, form of release and dosage

Enterofuril is an antimicrobial drug. The drug is used to eliminate bacterial infections that are diagnosed in the digestive system.

The medicine is in the form of a suspension and tablets. The suspension has a yellow hue and a banana flavor. The main active component of the drug is nifuroxazide, its concentration in five milliliters is two hundred milligrams. Also, the composition of the tool includes additional substances:

1. Carboxypolymethylene.
2. Sodium hydroxide.
3. Ethanol.
4. Banana flavor.
5. Methylhydroxybenzoate.
6. Lemon acid.
7. Sucrose.
8. Water.

The suspension is in a bottle of dark glass with a volume of ninety milliliters.

One tablet contains one hundred or two hundred milligrams of the active component and a number of additional substances:

• corn starch;
• sucrose;
• cellulose;
• magnesium stearate.

The drug is prescribed for the treatment of children and adults. Side effects of Enterofuril, reviews of the drug, as well as contraindications will be presented below.

Pharmacological actions

The active component of Enterofuril is nifuroxazide, it is referred to as 5-nitrofuran derivatives. It has an antimicrobial effect, which occurs due to a violation of the formation of proteins in the cells of microorganisms.

The medication has an extensive spectrum of action. It leads to the death of gram-positive and gram-negative bacteria. Despite the increased antimicrobial activity, the drug practically does not adversely affect the intestinal microflora.

After using Enterofuril, the active substance is practically not absorbed into the systemic circulation and produces a pharmacological effect, usually in the intestine. Nifuroxazide is excreted from the body with feces in unchanged form.

With intestinal infections of viral etiology, the drug reduces the likelihood of superinfection. After oral administration, Enterofuril is completely not absorbed from the stomach and intestines, about 99 percent is stored in the intestinal tract. Nifuroxazide and metabolites are eliminated from the body along with the contents of the stomach. The excretion rate depends on the dosage taken and the patient’s gastric and intestinal motility. Contraindications and side effects of Enterofuril in children and adults will be presented below.

The drug has an increased activity against the following bacteria:

1. Staphylococci.
2. Streptococcus
3. Clostridia.
4. Salmonella.
5. Shigella.
6. Proteus.
7. Enterobacter.
8. Campylobacter.
9. Yersinia.

It can be concluded that Enterofuril can eliminate any intestinal infection provoked by any of the above pathogens. And since this is absolutely all the microbes that can cause intestinal infections, the drug is effective in almost one hundred percent of diseases in small and adult patients.

An additional advantage, which determines the increased effectiveness of the drug in the elimination of intestinal infections, is that bacteria have almost no resistance to it. According to the instructions, "Enterofuril 200 mg" does not affect the normal intestinal microflora, so its use does not cause dysbiosis.

Moreover, with dysbiosis, which is associated with a large number of different non-pathogenic bacteria in the intestine, the drug is an effective tool, the course of treatment of which helps to eliminate the negative state in almost a hundred percent of cases.

What side effects of Enterofuril are most common? This will be discussed below.

The medication acts only in the lumen of the intestine, absolutely not absorbed into the bloodstream and without rendering systemic reactions. Due to the lack of absorption of the drug into the general bloodstream, it can be given even to infants. The drug is practically safe.

Indications

According to the instructions, Enterofuril 200 mg and suspension are indicated for the treatment of an infectious pathological process that is localized in the hollow structures of the digestive system. Most often these are such ailments:

1. Diarrhea (a disease in which the patient has frequent bowel movements, and the stool becomes watery).
2. Chronic bacterial diseases of the stomach and intestines.

The drug is also used for the complex treatment of diseases that are accompanied by bloating, unstable stools, intestinal obstruction, nausea.

What prohibitions does the drug have?

The use of Enterofuril is contraindicated in the presence of certain pathologies or conditions, which include:

1. Intolerance to the substance of the drug.
2. Violation of the digestion and absorption of carbohydrates in the intestine.
3. Age up to one month (for suspension).
4. Age up to seven years (tablets).

Before using the drug "Enterofuril" you must make sure that there are no contraindications.

How to apply the medicine?

According to the instructions, Enterofuril suspension for children is intended for oral use. To determine the exact volume of medication taken, a measuring spoon (five ml volume) is used, which is included in the kit.

Dosage and dosage regimen depend on age:

1. Children over seven years of age and adults - twenty milliliters per day, the dosage must be divided into four doses (every six hours).
2. Age from three to seven years - five milliliters three times a day (every eight hours).
3. Children from seven months to two years - ten milliliters per day, the dose should be divided into four doses.
4. According to the instructions, Enterofuril suspension for children from one month to six months has the following dosage - 2.5 milliliters from two to three times a day.

Shake the vial well before using the suspension.

How to take pills?

According to the instructions for use, Enterofuril capsules for adults must be taken in a dosage of eight hundred milligrams per day.

It is necessary to divide it into four uses. That is, the drug is used one tablet in two hundred milligrams or two tablets in one hundred milligrams at a time.

The children's dosage of Enterofuril 200 mg capsules is six hundred to eight hundred milligrams per day, that is, one pill in a dosage of two hundred milligrams three to four times a day.

Tablets can be taken for children from the age of seven. Before using the drug, consult a specialist.

Side effects

According to reviews, Enterofuril in the form of a suspension for children and capsules for adults is well tolerated by patients. Sometimes, when using a medication, allergic reactions may occur, which include:

1. Rashes on the skin.
2. Itching
3. Urticaria (skin disease, dermatitis of allergic genesis, which is characterized by the instantaneous onset of severely itchy blisters).
4. Quincke's angioedema (an acute condition characterized by a sharp appearance of local edema of the mucous cavity, subcutaneous tissue and the skin itself).

These unpleasant manifestations can occur both when using tablets, and when using a suspension. Side effects of Enterofuril in children or adults are extremely rare. The occurrence of signs of the development of negative reactions is considered the basis for the cancellation of Enterofuril and a visit to the doctor.

Features

Before starting treatment, you should carefully read the instructions for use of Enterofuril capsules and suspensions. There are several special instructions for the proper use of the drug, which include:

1. To eliminate severe diarrhea in a child with a suspension, measures should be taken that are aimed at rehydration therapy.
2. During the use of the medication, it is strictly forbidden to take alcohol.
3. If the drug is prescribed for breastfeeding, parents need to make sure that there is no shortage of digestive enzymes that are responsible for the breakdown of sucrose.
4. The active substance does not directly affect the working state of the cerebral cortex, as well as the speed of psychomotor reactions and the ability to work with mechanisms.

In drugstores, the suspension is dispensed without a doctor's prescription. If you have questions and doubts, you should consult your doctor before treatment.

Features of taking tablets:

• Throughout the course of Enterofuril therapy, alcohol intake should be excluded.
• The drug effectively relieves diarrhea and eliminates intestinal infection. It does not make up for lost fluid and electrolytes. Therefore, together with the use of the medication, rehydration treatment, both intravenous and oral, should be carried out. The fact is that diarrhea causes the loss of a large amount of fluid and electrolytes, which must be replaced as soon as possible in order to avoid the serious consequences of dehydration.

To resume the volume of fluid lost during diarrhea, saline should be regularly used.

The active substance "Enterofuril" is not absorbed into the general bloodstream from the intestinal lumen, therefore, there is no information about drug poisoning.

Analogues of Enterofuril

The drug has generics both in the spectrum of action and in the active component:

1. Adisord.
2. Ersefuril.
3. Stopdiar.
4. "Nifuroside."
5. Lekor.
6. "Nifuroxazide".
7. "Sulgin."
8. Levorin.
9. Sanguirythrin.
10. Ecofuril.
11. Phthalazole.
12. Loperamide.
13. "Bioflor".
14. Imodium.
15. "Lopedium."
16. Ersefuril.
17. "Furazolidone."
18. Enterol.

Before replacing the original drug with its analogue, consult a specialist.

How to store the drug?

From the instructions for use it is known that the shelf life of the suspension is 36 months from the date of issue. After opening the bottle, the medicine can be kept for no longer than fourteen days. For tablets, the shelf life is exactly the same as for the liquid form of the drug. The cost of the drug varies from three hundred to four hundred rubles.

Enterofuril or Stopdiar: which is better?

When choosing an effective remedy for diarrhea, people are usually lost. Most patients, referring to advertising or the opinions of acquaintances, have a choice: Stopdiar or Enterofuril. You must understand that both drugs are considered generics, and have one active substance - nifuroxoside. It perfectly eliminates the spread of microbes in the intestine, being an etiotropic treatment of intestinal infections.

Depending on the dosage, it has a bactericidal or bacteriostatic effect, and since the component is not absorbed in the intestine and does not penetrate into the systemic circulation, the drug is considered safe and rarely provokes adverse reactions. Both medicines (Enterofuril and Stopdiar) are recommended even for children, although they are given as a suspension in small patients.

People may not worry about the big difference in the cost or quality of the medicine. In fact, both medicines are considered absolute analogues, and there is no difference between them. That is why medical specialists can prescribe only the active component, giving the patient the right to independently choose a drug.

Enterofuril or Enterol?

Both medicines have a minimum of side effects. Therefore, they are excellent for the treatment of children and adult patients. But they still have differences.

For example, the active components of Enterol are living beneficial bacteria. Therefore, it can hardly be called a quality drug for the elimination of a number of serious bacteria and viruses. In most cases, it is prescribed for preventive purposes to prevent diseases or as a medicine that restores the intestinal microflora.

Therapy should always be started only after consulting a doctor. Only a doctor, having carefully examined a specific case, will be able to prescribe treatment correctly. Self-medication is strictly prohibited.

Enterofuril or Furazolidone: which is better?

Since Enterofuril and Furazolidone belong to the same group of nitrofuran, their spectrum of exposure to microbes is similar. Antimicrobial agents differ. In Enterofuril, it manifests itself in relation to enterobacteria, but is broader towards gram-positive microbes. This is the main difference between Enterofuril and Furazolidone.

In this regard, Enterofuril is prescribed in the following conditions:

1. Enteritis.
2. Gastritis.
3. Diarrhea of ​​bacterial etiology.

Can I stop taking Enterofuril and buy Furazolidone? It is impossible, because each medication has its own spectrum of activity. With these diseases and identified sources of inflammation, the use of "Furazolidone" will not have a positive result. Improper and irrational use of an antibacterial agent can lead to the transformation of bacteria and the emergence of resistance to antimicrobials.

Enterofuril has the least number of prohibitions; it can be used in patients with impaired renal function, since it is excreted by the intestines and excludes the burden on this organ. "Enterofuril" also does not exchange in the liver, does not need additional use of hepatoprotectors, as well as neuroprotectors, medicines to restore intestinal microflora. Negative effects of Enterofuril are associated with an allergy to active and additional trace elements, as well as dyspeptic disorders.

Enterofuril together with Furazolidone can be used when pathogens that are sensitive to both Enterofuril and Furazolidone have been identified after laboratory testing. In other cases, the simultaneous use of Enterofuril and Furazolidone is considered improper, causes an additional load on the liver and kidneys, increases the risk of formation of resistant bacteria strains and often provokes adverse reactions.

Enterofuril or Loperamide?

Both drugs have a number of similar properties:

1. Both medicines are prescribed for diarrhea and problems of the gastrointestinal tract.
2. They act directly in the intestines.
3. Single release form.
4. Release drugs without a doctor’s prescription.

Of course, there are a number of differences, mainly in the timing of the use of drugs.

"Enterofuril" is considered a more absorbable drug that stabilizes the intestinal microflora, gradually removing toxic components. The medication must be used for at least seven days to stabilize the functioning of the stomach. Loperamide can be used both once and as needed.

In any situation, it is better to prevent unpleasant consequences in the form of diarrhea, for this you only need to follow a number of rules, which are especially important to teach children:

1. Wash hands before lunch, dinner and breakfast.
2. Drink bottled water.
3. Do not purchase ready-made food in markets and train stations.
4. Products of animal and vegetable origin to keep, transport and cook in the kitchen on different cutting boards, which are marked specifically for meat, as well as fish and vegetables.

Opinions about the drug

Reviews about Enterofuril are mostly positive. The undoubted advantages of the medication are the following points:

1. Belongs to the group of antimicrobials, not antibiotics.
2. It is active against almost all types of infections.
3. It does not affect the intestinal microflora, and also does not cause digestive problems.
4. Increases immunity, activating its ability to resist various pathogens and increase the number of antibodies.

Another advantage of Enterofuril is that pathogens do not have resistance to it.

According to reviews, Enterofuril practically does not cause side effects for children. The drug is not absorbed from the stomach and intestines, does not affect the functioning of various organs and systems, and only the intestines are considered the place of its action. For this reason, the drug can be classified as safe means that can be used even by small patients and in rare cases, according to the testimony of a medical specialist, women in position.

According to reviews, Enterofuril for children is highly effective in the fight against infectious diseases of the gastrointestinal tract. In pediatrics, the medication is widely used in the complex treatment of bacterial diarrhea, rotovirus, vomiting, and also to eliminate the effects of poisoning.

The drug is in the form of a suspension, which allows it to be prescribed even to infants.