“Phenazepam” refers to the category of highly active tranquilizers that have anticonvulsant, anxiolytic, and central muscle relaxant effects. The positive principle of exposure to the human body significantly exceeds all analogues. The drug can be used as a sleeping pill. The anxiolytic effect of the drug is expressed in a gradual decrease in emotional stress, easing anxiety, fear and anxiety. To understand how much "Phenazepam" is excreted from the body, you need to study the composition and principle of action of the medication. This article will help.
Description
The drug "Phenazepam" is a multifunctional derivative of benzodiazepine. The product belongs to the category of highly active tranquilizers. Bromo dihydrochlorophenylbenzodiazepine is represented by the active substance of the drug, only if used correctly it has a positive effect on the human body. "Phenazepam" reduces the severity of stress, eliminates the excitation of the subcortical structures of the brain, and also inhibits polysynaptic spinal reflexes. The drug is often used as an anxiolytic, sedative hypnotic. Active substances have an anticonvulsant and muscle relaxant effect. Due to this, the patient’s emotional stress is reduced, fear and anxiety pass.
Composition and form of release
Information on how much "Phenazepam" is excreted from the body is described in the instructions for the drug. Today, this medication is available in two dosage forms:
A solution of 0.1% for intramuscular, intravenous injection. One carton contains 10 ampoules.
Tablets. The package can be 10, 25, 50 pills.
The instructions for the use of phenazepam tablets indicate that the main active ingredient is bromodihydrochlorophenylbenzodiazepine. Auxiliary components: calcium stearate, lactose monohydrate, potato starch, croscarmellose sodium.
In the injection solution contains 1 mg of bromodihydrochlorophenylbenzodiazepine. As auxiliary components, purified water, sodium hydroxide and hydrosulfite, distilled glycerin, polysorbate 80, povidone are used.
Pharmacological principle of action
Each patient should know how much "Phenazepam" is excreted from the body in order to avoid negative side reactions. This drug belongs to the category of psychotropic medications that suppress the central nervous system. Basic pharmacological effects of "Phenazepam":
Sedative. The medicine significantly reduces the severity of negative symptoms of neurotic origin.
Anxiolytic. It perfectly eliminates emotional stress, fear, anxiety and a feeling of constant anxiety.
Anticonvulsant. Prevents the spread of a convulsive impulse, but does not eliminate the excitatory focus.
Hypnotic. If the patient took into account the fact how much “Phenazepam” is excreted from the body, then he will be able to significantly reduce the time of falling asleep, improving the quality of sleep.
Central muscle relaxant. Reduces the intensity of transmission of nerve impulses, due to which there is a gradual relaxation of smooth muscles.
The instructions for the use of phenazepam tablets indicate that the active component of the drug quickly penetrates into the blood. The tool begins to act 30 minutes after administration. The maximum concentration of the drug in plasma is achieved 2 hours after administration. The elimination half-life varies from 6 to 18 hours. For those who want to know how long the phenazepam injection works, it should be noted that a significant improvement in well-being occurs in 15 minutes. This form of medication is most often used to treat serious illnesses.
What helps Phenazepam?
The medicine is actively used in modern medicine to combat various diseases of the nervous system, as well as chronic mental disorders. The drug is prescribed in the following cases:
Insomnia and other sleep disorders.
Individual forms of schizophrenia.
Psychopathic and neurotic disorders, which are accompanied by intense fear, increased anxiety and anxiety, emotional lability.
Nervous breakdowns.
Disorders of the autonomic nervous system.
Panic conditions.
Epilepsy.
Reactive psychosis.
Alcohol withdrawal.
Muscle stiffness, hyperkinesis, tics.
To understand why Phenazepam helps, you need to not only study the instructions, but also consult a doctor. Short courses of tranquilizers are prescribed to prevent acute emotional stress. Long-term therapy is necessary to combat chronic mental pathologies.
Contraindications
The drug "Phenazepam" can be used only after prior consultation with a psychiatrist or neurologist. The patient must study the instructions for the medication. The main contraindications:
Shock state.
Acute chronic obstructive pulmonary disease.
Angle-closure glaucoma.
Myasthenia gravis
Coma.
Children under 18 years old.
Pregnancy and lactation.
Acute respiratory failure.
Individual sensitivity to the components of the drug.
Acute depression.
Renal and liver failure.
Diseases of the brain.
- Patients are over 70 years old.
Instruction manual
Reception "Phenazepamum" should correspond to the dosage recommended by the manufacturer. 5 mg of the drug can be taken per day. This dosage should be divided into 2 doses. The maximum daily dose of the drug is 10 mg.
The treatment of the patient depends on the diagnosed disease:
With pronounced agitation, anxiety and fear, therapy begins with a dosage of 3 mg per day. Gradually, the amount of the drug is increased in order to ultimately achieve the desired therapeutic effect.
In case of alcohol withdrawal, “Phenazepam” is taken in a dose of 2.5 to 6 mg per day.
To combat epilepsy, the maximum concentration of the drug should not exceed 10 mg per day.
With insomnia, the medicine is used in a dose of 0.4 mg 35 minutes before bedtime.
In psychopathic and neurotic conditions, the initial dose of the drug is 1 mg. After 4 days, the concentration of the substance can be increased to 5 mg per day.
With pathologies with increased muscle tone, the drug is consumed in 3 mg 2 times a day.
To understand how long you can take "Phenazepam", you need to consider that the standard therapeutic course is 14 days. In some cases, the duration of treatment can be increased to two months. At the final stage, the dosage of the drug is gradually reduced.
Adverse reactions
If the patient has figured out how long the Phenazepam tablet works, this will help to avoid the most common mistakes. High activity of the active substance can trigger the development of ataxia (impaired coordination of movement), dizziness, drowsiness.
The main side effects:
Constipation.
Addiction to the medication.
Decreased blood pressure.
The development of drug dependence.
Decreased sexual desire.
Allergic reactions.
Impaired attention span.
If the patient began to notice a deterioration in overall health, then you need to stop taking the medication and seek medical advice.
The effect of the drug on the emotional state of a person
There are many indications for the use of Phenazepam tablets, but patients must remember that the drug has a strong effect on the central nervous system. In some cases, this is fraught with the following symptoms:
Increased aggressiveness.
Euphoria.
Bouts of rage.
Depressiveness
At the initial stage of treatment, the patient may have high spirits, but longer therapy is fraught with a significant deterioration in mood, nervousness, and aggressiveness. In some cases, there is a strong excitement, as well as an attack of psychosis. If these symptoms appear, stop taking Phenazepam.
Consequences of an overdose
With prolonged use of "Phenazepam" side effects are very difficult to avoid. If the patient exceeds the permissible dosage, then this is fraught with severe intoxication of the body. In such a situation, a person experiences depressed consciousness, respiratory and heart failure. Significantly increases the risk of coma, death.
The basic symptoms of an overdose:
Trembling limbs (tremor).
Increased drowsiness.
Lowering blood pressure.
The weakening of motor reflexes.
Depressed heartbeat.
Disorientation, confusion.
Involuntary rapid movements of the pupils (nystagmus).
The weakening of motor reflexes.
Shortness of breath, shortness of breath.
If at least one symptom of intoxication occurs, you need to conduct a classic gastric lavage, take a high-quality sorbent, and also seek help from the hospital. Only a doctor can prescribe drugs that support the functions of the respiratory and cardiac systems. Antidotes "Phenazepam" - "Anexat", "Flumazenil."
A good effect can be given by laxatives, which cope well with the elimination of all toxins from the body. In a hospital, infusion therapy is mandatory, which involves the introduction of a Ringer solution, glucose. The patient must drink at least 2 liters of still water per day. If there is a threat of respiratory or cardiac activity, then the patient is prescribed an effective antidote. The active substance is administered intravenously.
Pregnancy and lactation
The active substance "Phenazepam" has a toxic effect on the developing fetus, which increases the risk of congenital malformations when using the drug in the first trimester. The use of standard therapeutic doses in later pregnancy can cause depression of the central nervous system of the newborn baby. Long-term use of "Phenazepam" can provoke the development of withdrawal syndrome in the baby. Using the medication before childbirth can cause respiratory depression, hypotension, decreased muscle tone, hypothermia, and a weakening of the act of sucking.
Available analogues
Numerous side effects with long-term use of “Phenazepam” force patients to select other medications. The most popular analogues of the drug are the following drugs:
"Phenorelaxan."
The Phezipam.
Fenzitat.
"Fesanef."
"Elzepam."
Tranquesipam.
"Phenazepam" refers to the category of potent tranquilizers of the benzodiazepine group, which have a pronounced sedative, hypnotic, anxiolytic effect. Due to the specific action of the drug on the nervous system, a high degree of effectiveness is achieved in the treatment of many neurological and psychopathic pathologies, insomnia. The medication has a huge list of contraindications, which can cause serious adverse reactions. Long-term use is fraught with addiction and drug dependence.
That is why the sale of the drug from pharmacies without a prescription is strictly prohibited. "Phenazepam" can be taken only as prescribed by the doctor, observing the dosage. Otherwise, the patient may encounter unpredictable consequences that will negatively affect the work of the whole organism.
The principle of interaction with other medicines
The simultaneous use of Phenazepam with drugs from other groups is fraught with the fact that the active substance can enter into a chemical reaction. This entails a change in the effectiveness of drugs, an aggravation of common adverse reactions.
Interaction of "Phenazepam" with other drugs:
The effectiveness of "Levodopa" is reduced.
The inhibitory effect on the respiratory system of “clozapine” is enhanced. This situation is fraught with a complete stop of breathing.
Significantly increase the toxic effects of "Zidovudine" (a common antiviral agent that is actively used in the complex treatment of HIV). "Phenazepam" is not recommended to be combined with MAO inhibitors, as well as "Imipramine."
The action of antihypertensive drugs is enhanced.
The therapeutic effectiveness of antiepileptic drugs, sleeping pills, muscle relaxants, and also narcotic analgesics is increasing.
Application features
"Phenazepam" has a persistent and pronounced ability to cause drug dependence in a patient with prolonged use in large doses. Those people who abuse the drug suffer from frequent hallucinations, panic attacks, obsessive thoughts, and sleep disorders. Manufacturers of the medicine note that “Phenazepam” is prescribed with extreme caution in case of severe depression, as this drug can be used to implement suicidal plans.
The drug is forbidden to use for drivers, as well as for those people who maintain mechanisms that require accurate and quick reactions. The combination of "Phenazepam" with alcohol is fraught with a significant decrease in the effectiveness of the medication, increased its toxic effects, as well as the development of symptoms of overdose. The active substances of the drug inhibit breathing and cardiac activity.
Numerous patient reviews of "Phenazepam" indicate that addiction to the drug develops very quickly. Because of this, it becomes increasingly difficult for a person to do without a drug. In between pills, all negative emotions are significantly exacerbated, only the next pill of a powerful tranquilizer saves the situation.