The medicine "Carvedilol", according to patients, has a mild and effective effect. The drug belongs to the group of antihypertensive drugs.
Means "Carvedilol". Description
The mechanism of action of the drug is based on the blockade of beta 2-, beta 1-, alpha 1-adrenergic receptors. Describing the drug "Carvedilol", the instructions for use indicate its ability to moderately lower the conductivity, frequency and strength of the heartbeat, without causing sharp bradycardia. Blockade of alpha 1-adrenergic receptors causes expansion in peripheral vessels. With blockade of beta 2-adrenergic receptors, the tone in some vessels of the microvasculature, bronchi, as well as peristalsis and tone in the intestine, slightly increase.
The medicine "Carvedilol" instruction recommends for arterial hypertension.
The drug is prescribed inside. During the first day of therapy, the dosage is 12.5 milligrams in one dose. After the amount of the drug is doubled (25 milligrams). Also taken once a day. On the recommendation of a doctor, if necessary, the dosage of the drug "Carvedilol" application instructions can be increased. Do not take more than fifty milligrams per day. An increase in dosage should be carried out no more than once every fourteen days. For older patients, efficacy may be noted with 12.5 milligrams.
The side effects of the drug "Carvedilol" instructions for use include episodes of excessive decrease in pressure. These phenomena are noted at the beginning of therapy ("first dose syndrome") and with a subsequent increase in the amount of the drug taken. As a rule, these conditions are eliminated independently, without requiring dosage adjustment.
Subsequent use of the drug "Carvedilol" can provoke increased motility and tone of the intestine, bradycardia, headache, fatigue, weakness. Angina attacks, disorders in the peripheral blood flow, and the phenomenon of intermittent claudication are also likely . The side effects of the drug "Carvedilol" instructions for use also include exacerbation of the previously existing psoriatic process, urticaria, reactions similar to the development of lichen planus, allergic exanthema.
In rare cases, taking the drug can provoke leukopenia, nasal congestion, thrombocytopenia, increased heart failure, paresthesia (numbness), depression, and sleep disturbance.
The medicine "Carvedilol" is contraindicated in atrioventricular blockade of the second or third degree, shock, decompensated heart failure, bronchial asthma, liver failure, chronic lung pathologies complicated by bronchial obstructive syndrome, hypersensitivity to the drug. Not prescribed for lactation and during pregnancy.
special instructions
The medicine "Carvedilol" is prescribed with caution in patients with heart failure and coronary heart disease. In the presence of heart failure, it is necessary to conduct adequate treatment before using the drug in order to eliminate the manifestation of decompensation. In patients with coronary heart disease when taking the drug "Carvedilol" may decrease myocardial oxygen demand. In this regard, drug withdrawal is carried out gradually, in order to avoid the development of an attack of angina pectoris.
During treatment, it is recommended to stop drinking alcohol.
At the beginning of therapy and with an increase in dosage, one should refrain from carrying out potentially dangerous activities, including driving.
Before using the medicine "Carvedilol", it is necessary to study the annotation, consult a doctor.