In the article, we consider the indications for use and the price of Veroshpiron.
It is a potassium-sparing diuretic drug that can have a diuretic effect by blocking aldosterone. Its use is advisable if it is necessary to eliminate internal and external edema that develops with pathological changes in the liver and heart. It is able to have an indirect antihypertensive effect (lower blood pressure). May be prescribed to patients from 3 years. Inadmissible is the use of the drug by pregnant women and in the lactation period.
Indications for use of Veroshpiron are of interest to many.
Pharmacological forms
The manufacturer "Veroshpiron" is available in tablet and capsule forms, which are intended for oral administration. Veroshpiron tablets have a dosage of 25 mg, have a specific smell, their shape is round and flat. There is a chamfer on one side. Each pack holds 20 tablets. Veroshpiron capsules have a dosage of 50 mg, the active substance is enclosed in a gelatin shell of white-yellow color. 100 mg capsules are orange-yellow in color. The contents of the gelatin capsule is a white powder. Each package of capsules, regardless of their dosage, contains 30 pieces.
Before considering the indications for the use of Veroshpiron, we will study its composition.
Structure
The active ingredient in Veroshpiron is spironolactone, which is a competitive antagonist of the hormone aldosterone secreted by the adrenal cortex. The substance does not affect the function of the renal tubules, the speed of blood flow in the kidneys does not change. Against the background of its use, a diuretic effect develops, blood pressure decreases indirectly.
As auxiliary components in the manufacture of tablets are used: magnesium stearate, talc, silicon dioxide, lactose, corn starch. In the manufacture of capsules, additional components are: titanium dioxide, gelatin, dyes, sodium lauryl sulfate, corn starch, magnesium stearate, lactose.
Indications for use of Veroshpiron in the instructions are described in detail.
Pharmacological group
Veroshpiron is a drug that can affect kidney function. According to its pharmacological group, it is a potassium-sparing loop diuretic. The function of the renal tubules changes with the use of the drug due to blocking of aldosterone, which can affect the accumulation of fluid in the body.
Indications for use of tablets "Veroshpiron"
For adult patients, the drug is prescribed in order to eliminate edema and lower blood pressure, normalize potassium levels in the presence of hypokalemia. The drug is indicated for use in the following cases:
- Therapy and prevention of hypokalemia, hypomagnesemia, if other drugs are ineffective or provoke the development of undesirable effects due to their long-term use.
- Preliminary preparation for surgical treatment of primary hyperaldosteronism.
- Primary hyperaldosteronism.
- Another indication for the use of the drug “Veroshpiron” is arterial hypertension, which develops as a result of hypokalemia. In this situation, the drug is used as an element of complex therapy.
- Edema provoked by pathological disorders of the kidneys (with nephrotic syndrome).
- Puffiness syndrome accompanying cirrhosis of the liver (swelling of the extremities, ascites).
- Edematous syndrome accompanying chronic renal failure. It can be used as a means of monotherapy, or as part of a comprehensive treatment in conjunction with other medicines.
The list of indications for the use of Veroshpiron is quite extensive. It can be prescribed to prevent and treat paroxysmal myoplegia, accompanied by severe limb weakness due to the loss of potassium ions in the urine.
For children, medication can be prescribed from 5 years. Indications for use of Veroshpiron in babies are similar to those in adult patients. If there is an urgent need, a specialist can prescribe medication for children from 3 years.
Indications for use of Veroshpiron in gynecology: hyperandrogenism, polycystic ovary syndrome.
The use of the drug by pregnant women and in the lactation period is unacceptable. If necessary, the drug can be recommended to nursing mothers, however, before starting therapy, it is necessary to transfer the child to artificial feeding.
Contraindications
Do not take "Veroshpiron" if there are the following disorders or conditions:
- Addison's disease.
- Hypomagnesemia, hyponatremia, hyperkalemia.
- Lactation.
- Age up to 3 years.
- Pregnancy.
- Impaired lactase synthesis, lactose intolerance.
- Renal failure in acute form.
- Individual hypersensitivity to the main or additional components of the drug.
Caution should be taken if the patient has metabolic acidosis, diabetic nephropathy, he is shown anesthesia or local anesthesia, he is in old age.
Using Veroshpiron
The total daily dose of the drug can range from 25-400 mg, it depends on the pathology, the severity of its course, the individual body reaction to the therapy. Take the drug once or twice a day, only after eating.
In order to treat hypokalemia, adult patients are prescribed no more than 100 mg per day, hypertension - no more than 100 mg. The course of therapy can last at least 2 weeks. Only such a period of use will achieve therapeutic efficacy.
For the purpose of therapeutic effect on edematous syndrome, developing against the background of cirrhosis of the liver, kidney pathologies, congestive heart failure, the use of a daily dose of up to 200 mg is indicated. If the clinical case is severe, a dosage increase of up to 400 mg is allowed.
If the drug is used in preparing the patient for surgery and for the treatment of primary hyperaldosteronism, it is recommended to use up to 400 mg of the drug per day for a week.
Veroshpiron can be used as an element of maintenance therapy. The dosage is selected individually. As a rule, the maximum recommended dosage is systematically reduced twice a month until it becomes minimal, but causing the necessary effect.
Treatment of children using Veroshpiron should begin with a minimum dose, which should be determined based on the weight of the child. The therapeutic dose is up to 3 mg / kg, and the maintenance dose is up to 2 mg / kg. A day shows a single or double medication. If young children have difficulty swallowing the drug, it is possible to pre-crush the tablet or extract the contents from the capsule shell. The resulting powder is diluted with a tablespoon of water and given to the child.
Indications for use of the medicine “Veroshpiron” should be strictly observed. Otherwise, the development of side effects is not ruled out.
Negative impact
Against the background of the use of the drug, undesirable reactions can develop that are expressed by the development of the following conditions:
- Hyponatremia, hypokalemia.
- Heart rhythm disturbance.
- Gynecomastia in men, the development of erectile dysfunction.
- Violation of the cycle of menstruation, hirsutism in women.
- Urticaria, erythema.
- Decreased appetite, abdominal pain, nausea.
- Dizziness, headache.
- Asthenia.
- Increased weakness.
- Infertility.
As a rule, negative reactions develop at the initial stages of therapy, pass on their own within a few days.
If negative reactions are persistent, discontinue therapy and consult a doctor.
Interaction with other medicines
With the parallel use of Veroshpiron with NSAIDs, immunosuppressants, ACE inhibitors, aldosterone blockers, potassium-sparing medicines, hyperkalemia develops.
When using the drug in conjunction with alcohol, barbiturates, drugs, tricyclic antidepressants, antipsychotic drugs, ganglion blockers , the hypotensive effect is enhanced, a sharp decrease in blood pressure occurs.
Combined therapy with Veroshpiron and lithium preparations, digoxin enhances the toxicity of the latter. Experts also do not recommend the use of a diuretic in conjunction with other diuretics, as diuresis is significantly enhanced and tissue dehydration develops.
Special instructions for use
It is important not to use Veroshpiron for a long time and unreasonably. This will prevent the development of carcinoma and myeloid leukemia. During therapy should refrain from drinking alcohol.
At the initial stages of diuretic therapy, it is recommended to carefully carry out work related to driving and complex mechanisms.
We reviewed the indications for the use of the drug "Veroshpiron."
Price
This drug is inexpensive. Packaging means will cost 70-100 rubles. It depends on the region and the pharmacy network.
Overdose
If an overdose occurs, the patient develops convulsions, drowsiness, weakness, and loss of consciousness is not ruled out. In order to stop the toxic effects, gastric lavage should be performed, and sorbents (activated carbon, polysorb) should be taken. Then the patient is prescribed intravenous infusions of potassium-excreting diuretics, saline, insulin solution with glucose. If the overdose is severe, hemodialysis is indicated.
Analogs
If necessary, the drug can be replaced with Diuver, Lasix, Inspra, Spironolactone. All drugs have an effect similar to Veroshpiron.
Before replacing a medicine, it is important to consult a doctor.
Reviews
Patients in their reviews often note the effectiveness of the drug, however, at the same time, they pay attention that it is not worth abusing a diuretic, and it is necessary to take it only as directed by a specialist. This is due to the fact that the drug has a fairly wide list of contraindications, and against the background of use, negative reactions develop.
The drug successfully eliminates puffiness, is often prescribed in the field of gynecology in PCOS.
Often there are reports that Veroshpiron, thanks to its diuretic effect, is effective in reducing body weight, and some users claim that it helps fight hirsutism.
Nevertheless, despite the large number of positive responses, the drug should be used only after consultation with the doctor.
The article presented indications for the use of Veroshpiron and reviews.