Inflammation of the epidermis in most cases accompanies precisely skin diseases, more precisely - different types of dermatitis. Diseases mainly develop under the condition that certain pathogens affect the dermis.
"Beloderm" is a glucocorticosteroid drug, which is intended for the treatment of various inflammatory processes of the skin.
Structure
Beloderm is produced in the following dosage forms:
The first two types are produced in aluminum tubes of fifteen and thirty grams each. The tube is placed in a cardboard box with instructions for use.
The active ingredient in Beloderm ointment is betamethasone dipropionate. In one gram of the product, there are 640 micrograms of the main substance. Additional trace elements are:
- petroleum jelly;
- mineral oil.
The main active substance of the cream is betamethasone dipropionate.
Auxiliary components include:
- sodium dihydrogen phosphate monohydrate;
- chlorocresol;
- mineral oil;
- petroleum jelly;
- phosphoric acid;
- macrogol cetostearate;
- cetostearyl alcohol;
- sodium hydroxide;
- water.
Act
The active substance refers to synthetic glucocorticosteroids. Betamethasone has an anti-inflammatory and anti-allergic, antipruritic effect. In addition, it has vasoconstrictive, antiexudative and anti-proliferative (preventing the reproduction of bacteria) effects.
When applying a cream or ointment to the skin surface, an active trace element weakens the production and release of a biogenic amine or lysosomal enzymes - substances that are involved in the development of the inflammatory process and allergies. Betamethasone also reduces swelling.
From the instructions for the use of Beloderm spray, it is known that when applied to the skin, the medication has an instant effect on the source of inflammation, reducing redness of the skin, itching and irritation, as well as pain.
The absorption of the active trace element in the blood varies depending on the general condition of the skin surface, the presence of damage and inflammation (when using the drug on the damaged or inflamed skin, the active component is absorbed faster). Systemic absorption after topical application ranges from twelve to fourteen percent. About sixty-four percent of the active substance binds to blood proteins. The drug is removed, usually with bile.
In what cases can I use the drug?
"Beloderm" is prescribed for various skin lesions that need anti-inflammatory therapy with topical glucocorticosteroid medicines. For instance:
- Contact dermatitis (an inflammatory reaction of the skin to contact with an irritant).
- Atopic dermatitis (chronic non-infectious inflammatory skin lesions occurring with periods of exacerbations and remissions).
- Bullous dermatoses (a group of skin diseases that differ in development mechanisms, in the clinic, treatment and prognosis).
- Neurodermatitis (a chronic skin disease of a neurogenic-allergic type, occurring with periods of remission and exacerbation).
- Various forms of eczema (acute or chronic non-infectious inflammatory skin disease characterized by a diverse rash, burning sensation, itching and a tendency to relapse).
- Psoriasis (a skin disease of a chronic nature, which is accompanied by the appearance of raised red spots).
- Exudative erythema multiforme (recurrent skin disease, accompanied by the formation of spots and blisters on the skin and in the oral cavity).
- Red lichen planus (a skin disease of an unknown cause, manifested by chronic inflammation of the skin with the formation of a rash, vesicles).
- Discoid lupus erythematosus (chronic skin disease in the form of limited erythematous lesions covered with dense scales).
- Reaction to insect bites.
- Itchy skin.
Contraindications
"Beloderm" is prohibited for use with:
- Fungal and bacterial infections.
- Open wounds (violation of the integrity of the skin, resulting from the destruction of deeply lying tissues).
- Trophic ulcers (a defect in the skin or mucous membrane that occurs after rejection of necrotic tissue and is characterized by a torpid course, a small tendency to heal and a tendency to relapse).
- Varicose veins (expansion of the superficial veins of the lower extremities, accompanied by valve failure and impaired blood flow).
- Acne vulgaris (acne that occurs in connection with a general hormonal imbalance in the body).
- Rosacea (a chronic relapsing facial skin disease caused by angioedema).
- Near-mouth dermatitis (a pathological process that affects the skin in the mouth and chin).
- Chicken pox (a common childhood infection, accompanied by skin rashes in the form of vesicles and itchy skin).
- Tuberculosis of the skin (an infectious process in which the epidermis, dermis and subcutaneous fatty tissue are affected).
- Syphilitic rash (modification of the surface vessels of the skin).
- Post-vaccination reaction.
- Skin cancer.
- Individual intolerance to the active substance.
- Children under six months.
It is not recommended to apply the drug to the skin in the eye area, since the ingestion of an active trace element - betamethasone - on the mucous cavities of the organs of vision contributes to the occurrence of glaucoma, cataracts or fungal infections.
"Beloderm": instructions for use
Cream and ointment are used topically. The medication must be smeared with a thin layer on a dry, cleaned area of the skin. The number of applications - twice a day. In the area of coarsened and dense skin or in places where the drug is most quickly erased, Beloderm can be used more often. The duration of treatment should not be more than one month. A course may be repeated throughout the year.
In the treatment of chronic diseases and for the preventive purposes of returning the disease, it is necessary to apply the drug for some time after the disappearance of unpleasant symptoms.
Dressings that provide hermetic isolation of the damaged area of the skin are used only as prescribed by the doctor, since their use increases both the therapeutic effect of the ointment and its harmful effect on the body.
According to reviews and instructions for the use of Beloderm, the cream is used to eliminate acute inflammation on the skin. The drug in the form of ointment is prescribed for the treatment of chronic dermatoses, as well as dry and flaky lesions.
New form
According to reviews and instructions for use, Beloderm Express spray for external use is sprayed onto the inflamed or affected area of the skin in the amount necessary to cover the damaged surface, the agent is used twice a day. The duration of the course depends on the effectiveness and tolerability of the treatment, usually no longer than one month. In children and patients with damage to the surface of the skin of the face, the duration of therapy should not be longer than five days.
Side effects
In some cases, the use of Beloderm contributes to the development of negative reactions. For instance:
- burning;
- itching
- redness of the skin;
- acne
- skin atrophy;
- striae (skin defect in the form of linear stripes localized in places of the greatest stretch of the skin);
- hyperpigmentation (focal or diffuse accumulation of pigment in the layers of the skin, leading to darkening of its color on the body);
- hypertrichosis (a disease manifested in excessive hair growth unusual for this area of the skin);
- telangiectasia (persistent, long-term expansion of the superficial vessels);
- folliculitis (inflammation of the hair bulb).
Provoking factors include:
- prolonged use of the drug (more than twenty one days);
- treatment of large areas of the skin;
- the use of large dosages of the drug;
- use of ointment or cream on the surface of the skin with scratches, abrasions.
If adverse reactions occur, you must stop using the Beloderm preparation and conduct symptomatic therapy.
Signs of an overdose include impaired glucose metabolism, migraine. With the manifestation of these symptoms, discontinuation of therapy is also required, as well as procedures to restore the water-salt balance.
Features
During therapy with the Beloderm drug, it is important to pay attention to the following nuances:
- It is not recommended to use the medication for more than one week, since there is a chance of developing adverse reactions - acne, rosacea.
- The treatment of the skin in the folds should be short-lived, as the risk of striae increases.
- For liver diseases, only small dosages of the cream can be used without the use of a dressing.
- Beloderm does not affect the concentration of attention, and also does not interfere with driving and complex mechanisms.
- The use of the drug during the gestation of the child is possible only if the expected positive effect for the expectant mother is higher than the risk to the fetus.
- Beloderm can be used during breastfeeding, but only under the strict supervision of a doctor.
- Long-term use of Beloderm Express for the skin of the face is not allowed, since pink acne may appear.
According to the instructions for use, Beloderm for children can be used starting from six months, but with extreme caution.
The cost of the drug varies from 130 to 180 rubles.
Analogs
Cream "Beloderm," the instructions for use of which were discussed above, has a number of structural substitutes:
- "Elokom."
- "Flucinar."
- "Eloson."
- Silkaren.
- "Comfoderm".
- Akriderm.
- "Prednisol".
- Dexamed.
- Diprospan.
Akriderm
Hormonal medication that is used in the treatment of chronic inflammation of the skin. For instance:
- psoriasis;
- dermatitis;
- eczema
The drug can be produced in various forms in combination with antibacterial and antifungal substances:
- The drug "Akriderm GENTA" has a pronounced bacteriostatic effect, which is aimed at combating many gram-positive and gram-negative bacteria. The cream is used for recurring eczema, simple lichen, exfoliative, diaper rash.
- Cream "Akriderm GK" has an antibacterial effect due to the high concentration of gentamicin and antifungal action using clotrimazole.
The cost of the drug varies from 100 to 700 rubles.
Silkaren
Local pharmacological agent that has anti-inflammatory effect. This medicine provides a positive result in the elimination of a number of epidermal diseases. A drug in the form of a cream for external use is available. Silkaren improves derma health and eliminates unpleasant symptoms.
With extreme caution, apply the cream to the skin in the face. In addition, it is necessary to carefully treat Silkaren cream with occlusive dressings and over large areas of the epidermis.
The active trace element that is part of the drug is mometasone furoate. This component can be found in many drugs that are intended for topical use in inflammation of the dermis.
Opinions
Of course, Beloderm, the instructions for use and analogues of which we have reviewed in this review, is considered effective in dermatological inflammatory processes. But with prolonged therapy, abrupt cancellation of their use can lead to rebound syndrome (intense redness of the skin and burning).
In addition, it must be borne in mind that children are more likely to develop Itsenko-Cushing's syndrome when using Beloderm.
A long course affects the development and growth of the child, in connection with which the drug should be applied very carefully - in a small dosage and no longer than twenty-one days.
Reviews about the drug "Beloderm" are positive and indicate good tolerance and high efficiency.