Painful frequent urination, pain in the lower abdomen and lower back, nausea, chills are common symptoms in diseases of the urinary system, such as cystitis and pyelonephritis. The cause of this condition is the inflammatory process of an infectious origin, and it is impossible to cope with it without medical treatment. A medicinal substance called oxolinic acid will come to the rescue. It belongs to the first generation of quinolones - preparations of bactericidal action of synthetic origin. Oxolinic acid is part of the Gramurin preparation, which is widely used in the treatment of diseases of the urinary system.
Today, you rarely see a person who has not heard of antimicrobials or antibiotics. Some flatly refuse to take them, even if the medicine is prescribed by a doctor, while others, on the contrary, drink them on their own at the slightest hint of the disease, if only to return to duty as soon as possible. Drinking or not drinking is everyone's personal business, but if a decision is made to be treated with an antibiotic, then at least the instructions for use with the drug should be studied without fail. Ideally, with such symptoms, you should immediately seek help from a medical institution.
The action and interaction of matter
Oxolinic acid acts on the DNA of pathogens, disrupting their vital functions, as a result of which they die. The medicine is absorbed by the gastrointestinal tract, excreted unchanged through the kidneys.
Oxolinic acid reduces the effect of oral antiepileptic, antidiabetic drugs and anticoagulants metabolized in the liver. When interacting with the drug "Furosemide" there is an increase in antibacterial action.
Indications and Cautions
Antibiotics are always contraindicated in pregnant women. When breastfeeding, the baby is weaned for the duration of treatment. Oxolinic acid is no exception to the rule. Indications for use in patients, provided there is no hypersensitivity, are as follows:
- pyelitis;
- cystitis;
- bacteriuria;
- pyelonephritis;
- prevention of catheterization and cystoscopy.
The drug is strictly forbidden to use for the treatment of people with manifestations of epilepsy, other CNS disorders and liver diseases.
Side effects
When deciding to drink an antibiotic, you need to understand that the active component will affect absolutely all living microorganisms. In other words, not only harmful, but also beneficial bacteria will die. Therefore, it is important not to resort to treatment yourself. Only a specialist can evaluate the real expected benefits and the inevitable negative effects of a drug such as oxolinic acid.
Instructions for use contain a rather impressive list of side effects:
- nausea and vomiting;
- stomach ache;
- heartburn;
- diarrhea;
- insomnia or drowsiness;
- visual impairment;
- allergic reactions: skin rashes and redness, itching, swelling and urticaria.
Rules for taking drugs
The trade name for oxolinic acid is Gramurin. One tablet contains 250 mg of active substance.
The reception schedule is as follows:
- patients over 12 years of age are prescribed 500 mg three times a day;
- babies from three months to a year - 0.5-1 tablets per day, divided into 3-4 doses;
- from a year to three - 1-1.25 tablets;
- from three to six - 1.5–2.25 tablets;
- from 7 d to 12 years - up to 3 tablets per day.
It should be noted that the exact dosage for children is calculated based on body weight. The given intake regimen can be used only in the case when the weight of the child meets the established standards and the patient has no contraindications. Infants are treated under strict medical supervision.
Remember that self-medication can be hazardous to health.