It is no secret to anyone that antibiotics not only help cure infectious and other diseases, but are also extremely harmful to the liver and intestinal flora. However, it is quite difficult to do without their use in the process of combating microorganisms that are highly sensitive to them.
Today we will tell you about the diseases under which such an antibiotic is prescribed as Cefodox. Instructions for taking this medicine, its release form, cost and properties will also be presented in this article.
Composition, form, packaging of antibiotic
The cefodox antibiotic goes on sale in two different forms. Consider their composition and packaging in more detail:
- 100 and 200 mg film-coated tablets. Their composition includes such an active substance as cefpodoxime. In addition to it, the preparation also contains auxiliary components in the form of iron oxide, white OY-L opadri, croscarmellose sodium, magnesium stearate, microcrystalline cellulose, starch glycolate, silicon dioxide and sodium lauryl sulfate. The medicine is sold in aluminum blisters packaged in cardboard boxes.
- Powder Cefodox. The suspension, made of a porous mass, contains such an active ingredient as cefpodoxime. In addition to it, the medication contains additional elements in the form of an emulsion of simethicone, citric acid, sodium saccharin, xanthan gum, carboxymethyl cellulose, corn starch, hydroxypropyl cellulose, vanilla flavor, microcrystalline cellulose, silicon dioxide and sucrose. Medicinal powder goes on sale in bottles of 50 and 100 ml.
Drug action
What is the medicine “Cefodox”? The instruction says that this is a semi-synthetic antibiotic belonging to the 3rd generation of cephalosporin preparations.
The bactericidal effect of this agent on the human body is due to acetylation of the membrane transpeptidase of the bacterial cell wall.
High sensitivity to this drug is observed in many gram-negative microorganisms. It also adversely affects some gram-positive bacteria.
A slight sensitivity to the drug is noted in insensitive anaerobes.
It cannot be said that the active substance of this drug does not affect most strains of enterococci, clostridia, mycoplasmas, legionella and chlamydia, as well as strains of staphylococci resistant to methicillin.
Kinetic properties of the drug
Suspension and tablets "Cefodox" (100, 200 mg) are actively absorbed in the human digestive tract.
The bioavailability of this medicine is 52%. After ingestion, the drug enters almost all the secrets and tissues of the body, and subsequently accumulates in them (in the muscles, kidneys, lungs, bone tissue, liver).
It should also be noted that this drug penetrates into the cerebrospinal fluid. This happens through the capsules of abscesses.
The active substance of the drug - cefpodoxime, is not metabolized. It is excreted along with urine.
Indications for use
What is the purpose of prescribing the cefodox antibiotic for children and adults? According to experts, this drug is actively used for various infectious diseases that were caused by microorganisms that have high sensitivity to it.
So, the drug in question is prescribed for:
- bronchitis, pneumonia;
- tonsillitis, otitis media, sinusitis, pharyngitis, laryngitis;
- infectious lesions of the joints, soft tissues, skin and bone tissue;
- pyelonephritis, cystitis (moderate or mild);
- proctitis, urethritis and cervicitis, which is of gonococcal origin.
Contraindications
The medicine “Cefodox”, the price of which is about 450-550 rubles, is not prescribed for patients with hypersensitivity to its constituent ingredients.
It should also be noted that the medication in the form of tablets should not be given to children under 12 years of age. As for the suspension, it is not recommended for babies up to 5 months of age, as well as for people with lactase deficiency, galactose intolerance, or galactose and glucose malabsorption syndrome.
Antibiotic "Cefodox": instructions for use
The drug in the form of tablets is prescribed only to adult patients and adolescents from 12 years old.
In infectious diseases of the upper respiratory tract and genitourinary system, the daily dose of this medicine is 200 mg, and with pneumonia or bronchitis - 400 mg.
Depending on the dosage of the drug, it is taken once or twice a day. The duration of therapy is established by a specialist and depends on the characteristics of the disease.
Elderly people do not need to adjust the daily dose.
How to prepare a suspension of Cefodox? The instruction says that for this you must first shake the bottle, and then add cold water (boiled) to it. In this case, make sure that the liquid reaches the mark indicated on the tank.
It is desirable to add water to the powder in two doses, shaking the bottle vigorously and achieving a homogeneous mass.
It is advisable to take a drug suspension with food. The interval between her receptions should be about 2 hours.
If the drug was prescribed to a child from the age of five months, then its daily dosage should be 10 mg per 1 kg of weight. The maximum amount of the drug per day is 400 mg.
Side effects after taking
Cefodox tablets or suspensions may cause the following side effects:
- diarrhea, headache;
- vomiting, itching of the skin;
- nausea, rash;
- an increase in hepatic transaminases;
- violation of thrombocytopoiesis and leukocytopoiesis;
- an increase in blood urea and creatinine;
- eosinophilia.
Reviews about the drug and its analogues
Replace the antibiotic drug “Cefodox” with such means as “Cefpotek”, “Doktsef”, “Zinacef”, “Axef”, “Zocef” and others. However, you should not use these drugs on your own.
Adult patients, as well as parents of young children, leave mostly positive reviews about this medication. According to them, the Cefodox antibiotic acts quite quickly, especially with infectious diseases of the urinary system and upper respiratory tract. In addition, it effectively manifests itself in bronchitis and other inflammatory processes.
It should also be noted that the tool in question contributes to the instant disappearance of such unpleasant symptoms as pain in the body and high fever.
As for the side effects, after taking Cefodox they are extremely rare.