In the treatment of malignant neoplasms, in combination with radiation therapy, the most commonly used drug is Temodal (temozolomide). It refers to alkylating substances that penetrate into DNA molecules, bind to them and do not allow two chains of DNA molecules to separate from each other, which prevents the growth of the tumor.
You will learn more about how the named medicine is used, what the price is for Temodal, and where you can buy it cheaper.
Where can Temodal buy more profitable
The well-known Indian company Natco, under an official license, produces a generic brand name drug called Temonat. This drug has the same active substance and a completely similar effect. But it costs much cheaper, since its price does not include the cost of development, research and advertising promotion.
So, the price in Temodal in Russia, depending on the dosage form, is in the region from 15,000 to 50,000 rubles. Temonat Buyers Site It will cost much cheaper, for this you will only need to present a document on the need for this treatment.
Indications for use
Temozolomide is most effective in the following pathologies:
- with glioblastoma multiforme, first detected;
- malignant glioma, in case of relapse that occurred after standard treatment;
- metastatic widespread melanoma.
In the latter case, the drug is used as a first-line therapeutic agent.
Dosage and route of administration
Attention, the described tool is used only in stationary conditions and is prescribed only by a specialist!
Temodal is taken on an empty stomach, an hour before meals. Capsules do not open and do not chew, but are swallowed whole, washed down with water (at least a glass).
Application features
Treatment with the drug "Temodal", the instructions for which are presented to your attention, course. In the process, the patient undergoes laboratory tests to determine the effectiveness of therapy.
Cancel the drug or reduce its dosage, guided by a special scheme that takes into account the patient's condition. The total duration of treatment can reach 2 years. If during this time the tumor did not stop growing, treatment is stopped.
Security methods
As mentioned above, capsules with the drug can not be opened. Avoid contact with skin or mucous membranes. If this happened, it is urgent to rinse this place with water.
The drug must be carefully hidden from children, as accidental intake of Temodal capsules by a child may be fatal for him.
Contraindications
The described tool in certain cases is not prescribed:
- with high sensitivity to temazolomide or to other components of the drug;
- in the case of a significant decrease in blood leukocytes and platelets;
- during pregnancy and during feeding;
- children up to three years of age with recurrent malignant glioma and up to 18 years of age - with first detected glioblastoma (multiform) or malignant melanoblastoma.
With caution, Temodal is used in patients older than 70 years and patients suffering from severe hepatic or renal failure.
Side effects
Since the described drug is potent, its use causes a number of side effects. These include:
- tachycardia;
- sleep disorders
- state of increased anxiety;
- candidiasis in the oral cavity;
- memory impairment;
- weakness;
- decreased attention, etc.