In the article, we consider the instructions for use, reviews and analogues to the drug “Cyanocobalamin”. What is this remedy? Vitamin B12, or “Cyanocobalamin,” takes part in hematopoietic processes, as well as in protein synthesis and metabolism, enhances bone growth in children and helps to preserve mental abilities in older people.
Indications
According to the instructions for use, "Cyanocobalamin" is prescribed for the treatment of the following diseases:
- chronic anemia, accompanied by a deficiency of vitamin B12;
- chronic hepatitis;
- Addison-Birmer disease;
- cirrhosis of the liver;
- impaired renal function;
- prolonged fever;
- alcoholism;
- polyneuritis;
- neuralgic attacks;
- Down's disease;
- cerebral palsy;
- amyotrophic sclerosis.
In addition, doctors often prescribe a drug for the complex treatment of skin diseases:
- with psoriasis;
- with herpetiform dermatitis;
- with a severe variety of photodermatitis;
- with atopic dermatitis.
As an additional tool, “Cyanocobalamin” is used in the following situations:
- all types of radiation diseases;
- severe migraine;
- intestinal malignant tumors;
- prolonged infections and complications arising from their soil;
- treatment of all kidney diseases.
Instructions for use with Cyanocobalamin are very detailed. The drug is also used as a preventive measure to avoid the following diseases:
- pathological gastric diseases;
- defects in the absorption of vitamin B12;
- problems in the functioning of the intestines;
- the occurrence of malabsorption syndrome;
- Crohn's disease.
Side effects of the drug
In accordance with the instructions for use, “Cyanocobalamin” in injections and tablets can provoke the development of adverse reactions:
- allergy to the composition of the product;
- the occurrence of urticaria;
- tachycardia attacks;
- frequent dizziness;
- overexcitation of the body as a whole;
- the occurrence of cardialgia;
- hypercoagulation during the use of a large dose;
- disorders of purine metabolism in the human body.
Contraindications
You need to know about those cases when the use of the drug can harm the patient's health and worsen his general condition. Instructions for use with "Cyanocobalamin" indicates that it should not be used in the following cases:
- when the patient has an allergic reaction to any substance in the composition;
- with thromboembolism;
- with erythremia;
- during pregnancy;
- with erythrocytosis;
- when breastfeeding a baby;
- care should be taken with angina pectoris.
The use of the drug for the treatment of pregnant women
Experts categorically prohibit the use of “Cyanocobalamin” to women at any stage of pregnancy. Exposure to vitamin B can be a source of danger for the unborn child. In addition, this drug cannot be used during breastfeeding. Otherwise, the active substance is able to pass through milk into the child’s body and harm the baby’s health.
Features of interaction with other drugs
Specialists are obliged to warn the patient about which drugs Cyanocobalamin cannot be combined with. Concomitant use can cause complications or side effects. These include the following dangerous interactions:
- concurrent use of ascorbic acid;
- the use of “Cyanocobalamin” at the same time as heavy metal salts is prohibited;
- specialists do not prescribe medication with Riboflavin;
- any salicylates will reduce the absorption of the drug “Cyanocobalamin”;
- you can not use drugs that enhance blood coagulation;
- mixing of vitamins B1, B6 and B12 in one syringe is prohibited;
- when combining several types of injection solutions, allergic reactions occur.
Drug overdose
What else does the application instruction for Cyanocobalamin tell us? When using the medication according to the established therapeutic course, an overdose will not occur. However, with frequent use of the drug without medical prescription, the following complications may begin:
- disturbances in the activity of the heart;
- pulmonary edema;
- the occurrence of vascular thrombosis;
- the appearance of urticaria;
- if the overdose is large, anaphylactic shock may occur.
If the first undesirable symptoms appear, you should immediately contact a medical institution. The specialist will prescribe symptomatic therapy and will constantly monitor the patient's condition. The hospital can be abandoned if all the symptoms recede.
Drug dosage
The drug is in the form of an injection solution. To treat a lack of vitamin B12, experts prescribe it in a dosage of 200 mcg per day. The treatment course is set individually until the patient recovers completely.
According to the instructions for use, "Cyanocobalamin" in tablets is also produced.
During the treatment of anemia, 500 μg of the drug should be administered at a time. In the first week, the patient should be injected every day. Then you can switch to a simpler treatment course and administer the drug every five days.
In the treatment of serious diseases, the drug “Cyanocobalamin” should be introduced into the canal of the spinal cord. First, a small dosage is taken - 30 mcg. The dose should be increased through each subsequent injection. The drug should be administered as follows: 50, 100, 150, 200 mcg. The procedure should be performed every three days. The drug is administered by the intralumbal method. The standard treatment course includes from seven to ten injections. When a serious condition recedes, it is necessary to carry out maintenance therapy. "Cyanocobalamin" is administered at 100 mcg twice a month. If the patient has neurological symptoms, it is necessary to increase the dosage of the drug to 300 mcg and inject four times a month.
If the patient suffers from iron deficiency, anemia may occur in this condition. It is necessary in this situation to do injections three times a week, using 100 μg of the drug at a time intramuscularly. Instructions for use for injections "Cyanocobalamin" must be strictly observed.
For the treatment of neurological diseases with a pain attack, 300-400 mcg of the drug per day should be administered to the patient. If rapid improvement is observed, the dosage may be reduced to 100 mcg. Most often, the therapeutic course for such an illness is two weeks. If a patient has nerve injuries, injections should be given every two days. The treatment course lasts forty days, while 300 μg of the drug is administered.
To cure cirrhosis, you need to put injections of 70 mcg daily. The course of therapy lasts from twenty to forty days. You can also drive 100 micrograms every two days.
For the treatment of liver diseases (hepatitis, cirrhosis), you can inject vitamin or take it in tablets at the rate of 30-60 μg of substance per day. Prescribe treatment course. It is possible to use up to 40 days.
This confirms the instructions for use for the drug “Cyanocobalamin”.
Analogues of the drug
Specialists can prescribe a drug similar to Cyanocobalamin for complex treatment. The medication will have a similar effect and have a positive therapeutic effect. Most often, such drugs are prescribed if the patient has an allergic reaction to Cyanocobalamin. A complete list of analogues includes: Medivitan; Neurocobal; "Vitamin B12" in the form of an injection liquid; "Triovit"; "Neuromin."
special instructions
Before prescribing the use of “Cyanocobalamin” in ampoules according to the instructions, a deficiency should be diagnosed as it can mask the lack of folic acid. During treatment, monitoring of peripheral blood data is required: it is necessary to determine the degree of concentration of reticulocytes and iron content on the 5-8th day of the therapeutic course. During the first month of treatment, one to two times a week and then two to four times a month should monitor the number of red blood cells, color indicator and hemoglobin level. Remission is achieved if the erythrocyte content increases to 4-4.5 million / μl, they acquire normal sizes in diameter, as well as eliminating poikilocytosis and anisocytosis and normalizing the degree of concentration of reticulocytes after a reticulocytic crisis occurs.
If hematologic remission is achieved, peripheral blood counts should be determined at least once every 4-6 months. In the presence of angina pectoris, as well as the patient’s tendency to form blood clots, the drug “Cyanocobalamin” must be used in a dosage of up to 0.1 mg per administration. It is advisable to use the medicine for a long time against the background of pernicious anemia and during surgical interventions on the gastrointestinal tract. The beginning of treatment for megaloblastic anemia showed that secondary arrhythmias occurred in relation to hypokalemia, which is why potassium content should be monitored during this period. When used by the elderly, there were no undesirable symptoms other than those described above. Most antibacterial agents and antimetabolites can affect the results of quantitative concentrations of vitamin B12 using a microbiological technique.
Reviews about the drug
According to many patient reviews, “Cyanocobalamin” is an effective tool that is used to increase hemoglobin content, improve well-being, and bring sleep to normal. Patients also indicate that the drug helps to strengthen the immune system, reduce pain with neuralgia and damage to the trigeminal nerve, improves blood formation and blood circulation. Many patients note that "Cyanocobalamin" allows you to get good results when it is used to accelerate the growth of hair and nails. Often, the solution is used as a component in masks or in pure form, rubbed into the roots of the hair, so that they are strengthened, fall out less and become shine, dandruff disappears. The disadvantage of the drug is the possible occurrence of side effects in the form of allergies. In some cases, patients complain that the neck is quite difficult to saw off in the ampoule.
We reviewed the Cyanocobalamin product instructions for use and reviews.