The heart and blood vessels of a person have a very complex structure. Therefore, during the appearance of various ailments, it is important to use complex therapy with the use of several drugs. Therefore, you need to know which is better: Mexidol or Actovegin.
To solve this dilemma, it is important to thoroughly familiarize yourself with the effect of medicines, their structure, as well as instructions for use.
Modern medicines Mexidol and Actovegin can be used in similar situations, so they are usually prescribed at the same time to increase the positive effect of treatment.
But in order to understand how compatible these drugs are and in the treatment of which diseases their general use is allowed, it is necessary to carefully read the instructions for use of each remedy.
The human cardiovascular system is quite complex, so when various diseases occur, complex therapy with the use of different drugs is often required. What is the composition of Mexidol and Actovegin?
Characterization of Mexidol
The drug belongs to the antioxidant agents of modern time and has a wide range of effects. This medication improves the process of brain metabolism, microcirculation, and also reliably protects cells from the harmful effects of harmful toxic microelements, which are formed subsequently by an improper metabolism.
This component allows you to use it for a variety of pathologies of the central nervous system. Can I inject Actovegin and Mexidol at the same time? In addition, the drug is also distinguished by other properties important for the treatment of various ailments, namely:
- Nootropic, that is, it activates the work of memory and increases mental activity.
- Hypolipidemic, which helps to apply it to normalize cholesterol in blood plasma.
- Membrane-protective, which provide protection for the cardiovascular system, and regenerating the lipid component of the cell membrane.
- Anticonvulsant and sedative effect.
- Antihypoxic, which can eliminate oxygen starvation of tissues.
Injections "Mexidol" with "Actovegin" together can be used to treat various neurological diseases. The combination of these drugs is often necessary for such pathological processes:
- Chronic arterial disease of the elastic and muscular-elastic type, resulting from a violation of lipid and protein metabolism and accompanied by the deposition of cholesterol and some fractions of lipoproteins in the lumen of blood vessels.
- Vegetative-vascular dystonia (a complex of functional disorders, which is based on a violation of the regulation of vascular tone by the autonomic nervous system).
- Acute disorders of blood microcirculation in the brain.
- Strokes (acute cerebrovascular accident causing damage and death of nerve cells).
- Dyscirculatory encephalopathy (involves a slowly progressing multifocal or diffuse vascular lesion of the brain, as well as their combination).
Due to the fact that Mexidol improves metabolic processes due to lactose, which is part of its structure, it has the ability to lower a person's susceptibility to stress. This drug is independently used in psychiatry for the treatment of alcohol withdrawal syndrome and to eliminate diseases that are associated with the appearance of internal anxiety.
In addition, the medication is often included in complex therapy during the elimination of various purulent and inflammatory processes that occur in the space located in the body below the diaphragm and completely filled with abdominal organs.
Structure
"Mexidol" in its composition has one active substance - ethylmethylhydroxypyridine succinate. The medication is produced in two dosage forms, which helps to use it in accordance with the current therapeutic situation. The drug can be bought:
- in tablets of one hundred twenty five milligrams;
- in a solution of two or five milliliters, which is packaged in ampoules made of special opaque glass.
The active trace element is contained in the volume of fifty milligrams per milliliter of solution. Other excipients are water for injection and sodium metabisulfite, which is a chemical substance that can kill microbial cells or inhibit their growth. The tablets have a biconvex shape, can be milky or cream in color. They additionally include:
- Lactose monohydrate, which activates the central nervous system and supports the normal structure of the biological flora in the intestine.
- A cellulose derivative that is used as a micronutrient binder.
- Magnesium stearate, which is used as a stabilizer.
Recommendations for use
What is Mexidol from? The drug is prescribed only by the attending doctor after conducting certain studies and making an accurate diagnosis.
As a rule, with various pathological processes, the dosage and dosage regimen of the drug can vary significantly. For example, in complex therapies for acute failures of microcirculation in the brain for a month, the drug can be used in droppers in the following concentrations:
- in the first fourteen days to four times a day, from two hundred to five hundred milligrams;
- in the second two weeks, up to three times a day, from two hundred to two hundred and fifty milligrams.
Is Mexidol used intravenously?
You can use the solution both intramuscularly and intravenously. That is, the drug can be used for injections and droppers.
Dosage is prescribed by a medical specialist in accordance with the course of therapy for a particular disease, but its maximum volume should not exceed 1200 milligrams per day. For intravenous infusion, a special solution for administration is prepared, in which sodium chloride is added as an auxiliary trace element. This medication is best administered slowly. Injections are made for five to seven minutes, and infusions are carried out from forty to sixty drops per minute.
In addition, the drug can be used intravenously for therapy in the following situations:
- To implement the prevention of vascular lesions of the brain, dosing can vary from 200 to 250 milligrams twice a day for fourteen days.
- To eliminate mild cognitive lesions and eliminate anxiety, it is necessary to take one hundred three hundred milligrams of the drug per day, the duration of therapy is from two weeks to one month.
- For the treatment of withdrawal symptoms, the dose can vary from two hundred to five hundred milligrams two to three times a day, the course lasts from five to seven days.
The dose of Mexidol in the elimination of acute purulent inflammation that occurs in the abdominal cavity, the doctor prescribes a purely individual, assessing the general condition of the person and the severity of the disease. The medicine can be used in the form of infusions both before the operation and after it.
Side effects
After taking the capsules, various dyspeptic disorders can be observed:
- Pain in the epigastric zone.
- Flatulence.
- Unstable chair.
This drug is characterized by excellent tolerance, therefore, negative phenomena, according to reviews, occur extremely rarely. According to statistics, adverse reactions most often occur when taking Mexidol in the form of a solution.
In addition, individual allergic reactions and an increase or decrease in blood pressure in people were recorded by doctors. It is extremely rare, according to patients' reviews, uncoordination of movements may appear. With drug poisoning, increased drowsiness is noted.
Description of Actovegin
It is a powerful medication that can affect the processes of tissue metabolism. The main effect of the use of the drug is that it can protect the tissues and organs of the body with insufficient blood supply. Which is better - Actovegin or Mexidol?
The drug is made on the basis of a natural substance, its active ingredient is an extract freed from protein, which is obtained from the blood of calves.
Indications
The drug along with Mexidol can be prescribed when the following pathological processes are eliminated:
- Circulatory disorders of the brain.
- Circulatory disorders with damage to brain tissue.
- Peripheral neuropathy.
- Damage to blood vessels caused by an upset of nervous regulation.
- Skull injuries.
As an independent drug, Actovegin can be prescribed for the following diseases and conditions:
- Disturbances of peripheral microcirculation.
- Ulcers of various origins.
- Chemical and thermal burns.
- The death of soft tissues as a result of constant pressure, accompanied by local circulatory disorders and nervous trophism.
- Radiation diseases.
- Diseases of the cornea.
In what dosage forms is Actovegin produced?
The drug is produced in the following dosage forms:
- capsules;
- solutions for injections;
- ointments.
In most cases, injections are prescribed for the treatment of various pathologies of the cardiovascular system. The solution is light yellow in color, the color intensity. For injection, the solution is placed in ampoules of two, five and ten milliliters. For infusions, ten and twenty percent solutions with sodium chloride are used in 250 ml vials. After opening the ampoule or vial, the remaining solution must not be stored.
Dosage is always prescribed by a medical specialist and depends on the severity of the disease. Most often, treatment involves the use of the maximum dosage at the initial stage of therapy, which as a result gradually decreases, and over time is replaced by capsules. The course should not be longer than four months.
Tablets are usually coated and contain the main active ingredient in a volume of two hundred milligrams. They must be swallowed whole with water. At the beginning of therapy, the content of the active component in most cases is six capsules per day. After stabilization, it is recommended to take one capsule per day for preventive purposes for some time.
Are there other forms of release?
Actovegin is also made in the form of ointments and gel applied externally. Their compositions differ in the concentration of the active trace element. Ointments and gels are recommended for use in the following situations:
- Twenty percent ointment is prescribed for severe diseases of the skin.
- A five percent gel has a milder effect and is often prescribed after radiation therapy for benign lesions on the surface of the skin.
What contraindications does Actovegin have?
A large number of reviews confirm that Actovegin is well tolerated. But, on the other hand, this drug has more prohibitions in comparison with Mexidol. The drug is not recommended for use in the presence of hypersensitivity to any trace element "Actovegin". Allergic reactions can occur in the form of itching and rash. In severe situations, anaphylactic shock may occur.
Comparison of Mexidol and Actovegin
Treatment with these drugs improves the general condition of the patient. Talking about which of these two medicines is better is not entirely correct. They have similar effects, are fully compatible and, when combined, increase the effectiveness of the treatment of diseases such as:
- Stroke conditions (an acute disease, the essence of which is an acute circulatory disorder in any part of the brain).
- Pathologies of peripheral blood supply.
- Head injuries.
It is necessary to focus on the fact that due to the fact that Actovegin is produced on the basis of plant microelements, it often provokes allergies. What is the compatibility of Actovegin and Mexidol?
It is important to understand that when used in complex treatment, it is better not to inject both medicines in the same syringe, since the active components can combine with each other and change the structure of the drug as a whole. This can not only reduce the effectiveness of the course, but also, more dangerous, cause allergies. Each drug must be injected with a separate syringe.
Opinions
Reviews of people tell that the combination of medicines instantly leads to positive changes in the process of therapy. Drugs accelerate the rehabilitation of patients, especially at a young age.
Which remedy is best for eliminating a specific disease can only be decided by a medical specialist after examining the patient and making a diagnosis.