Unfortunately, allergies are a very common problem today. And quite often, people are faced with such an unpleasant phenomenon as urticaria. Of course, modern medicine offers a lot of tools that can alleviate the condition of the patient. And quite often, doctors recommend Glencet to their patients. Instructions for use, indications and contraindications, prices and reviews are precisely those aspects that are of interest to many readers.
Composition and form of release of the drug
Naturally, many patients are interested in additional information about medications prescribed by a doctor. The drug "Gletset" is available in the form of biconvex oval white tablets, film-coated.
The main active substance of the drug is levocetirizine dihydrochloride. Each tablet contains 5 mg of this component. The core also contains microcrystalline cellulose, colloidal silicon dioxide, lactose monohydrate and magnesium stearate. The film membrane consists of macrogol - 400, titanium dioxide and hypromellose.
The tablets are placed in blisters. In the pharmacy you can buy blisters for 7, 10 or 14 tablets.
Description of pharmacological properties
The main active substance of the drug, levocetirizine, is the enantiomer of cetirizine. It acts as a competitive histamine antagonist, only its similarity to H1 receptors is two times higher than that of cetirizine.
This drug affects the histamine-dependent phase of an allergic reaction, and also limits the release of inflammatory mediators, reduces vascular permeability and slows down the eosinophil migration process. Thus, this medicine prevents the development of an allergic reaction or facilitates its course if it has time to manifest itself. Also, the drug has antipruritic and antiexudative properties.
After taking the medicine, it is rapidly absorbed, its bioavailability is 100%. The maximum concentration in the blood is observed after 45 - 55 minutes. The active substance is 90% bound to plasma proteins. The medicine is excreted by the kidneys. Complete elimination from the body occurs within 96 hours after administration.
The drug "Gletset": indications for use
This drug is widely used in modern medicine. In particular, it is effective in the treatment of urticaria, including its idiaopathic forms. Tablets are often prescribed to patients in the presence of Quincke's edema.
There are other cases in which it is advisable to use the drug "Gletset." Indications for its use are also any allergic reactions, including dermatoses, skin redness, accompanied by itching and burning.
The drug "Gletset" (tablets): instructions for use
In no case should you use these pills without the knowledge of your doctor. Only a specialist can prescribe the drug "Gletset" to the patient. Instructions for use contain only general information.
Tablets can be taken both on an empty stomach and after eating - this does not affect their properties. Children over six years old, as well as adult patients, take one tablet per day. The presence of chronic renal failure requires some adjustment - such patients, as a rule, take one tablet every 2 to 4 days. The duration of therapy is determined by the doctor. In acute allergies, the drug is taken until the symptoms disappear completely. But chronic processes require a longer treatment - it can last up to 18 months.
Are there any contraindications?
Is it possible for all people suffering from allergies to take the medicine "Gletset"? The instructions for use confirm that the drug has some contraindications, which should be familiarized with before the start of therapy.
This medicine is not prescribed for patients suffering from hypersensitivity to any of the constituent components. Also, therapy is contraindicated during pregnancy and lactation. The drug has some age restrictions - it should not be taken for children under six years of age.
Contraindications also include a severe form of chronic renal failure, glucose-galactose malabsorption, galactose intolerance, and lactase deficiency.
Are side effects possible?
Is there a possibility of complications while taking the drug "Gletset"? Instructions for use indicate that some adverse reactions are possible, so you should read their list.
In some cases, disorders of the central nervous system are manifested. Sometimes patients complain of increased fatigue, drowsiness, headache. Such reactions as convulsions, aggression, increased arousal, asthenia, hallucinations, and depressions are much less common.
Gletset tablets sometimes cause some malfunctions of the digestive system. In particular, the appearance of dryness of the oral mucosa, as well as nausea, abdominal pain, diarrhea, is possible. Very rarely, hepatitis develops during therapy.
There are other side effects. In particular, some patients complain of palpitations, difficulty breathing. Perhaps the appearance of tachycardia, myalgia, weight gain. Sometimes during analyzes, a change in the normal functional liver samples is detected.
In the presence of hypersensitivity, the drug can cause an allergic reaction, which is accompanied by swelling, skin redness, itching, angioedema, and in extremely severe cases - anaphylactic shock.
Is an overdose possible?
Many patients are interested in the question of whether an overdose of the Gletset drug is possible. Instructions for use indicate that such cases are indeed recorded, although extremely rarely.
Most often, while taking too much of the drug, increased drowsiness occurs. Children also had symptoms such as increased irritability and anxiety.
There is no specific antidote to date. Patients undergo gastric lavage, after which they give activated charcoal or other sorbents. In the presence of any other disorders, symptomatic therapy is performed.
Analogs and substitutes for medicine
For one reason or another, this medicine is not suitable for all people. And in such cases, the question of the availability of analogues becomes extremely important. Of course, if necessary, Gletset tablets can be replaced. For example, Xizal, Suprastinex, as well as Levocetirizin-Teva, Cesera are considered quite good anti-allergic medicines. Doctors recommend taking Aleron, Tsetrilev, Alerzin, Zenaro drugs for some patients. In fact, there are a lot of similar drugs, you should not try to choose the right remedy yourself - only the doctor can tell the most effective analogue.
How much is the drug?
The price of a medicine is important for many patients. You need to understand that the exact figure will depend on many factors, including the manufacturer, the pharmacy you choose, the city of residence, etc. A pack of 7 tablets costs about 260 rubles. For a blister with 10 tablets you will have to pay a little more - about 300 rubles. But the package with 14 tablets "Gletset" costs about 450 - 480 rubles. It is also worth considering that in most cases one blister is enough to undergo a full course of treatment.
Reviews of patients about the drug "Gletset"
What is Glencet actually? Reviews are a valuable source of information about a product. Therefore, many patients are primarily interested in precisely these data.
So what do people who have already managed to test the antiallergic agent Gletset say. Reviews are for the most part positive. Indeed, noticeable improvements can be noticed already after the first pill - allergy symptoms become less pronounced. In addition, due to their small size, they are easy to take. The reception mode is also very convenient. And the advantage is that tablets can be taken even by children. Naturally, like any medication, this medicine has contraindications, so be sure to read the instructions before taking it. Adverse reactions are possible, but are relatively rare.
The disadvantages of the drug can only be attributed to its price, since there are cheaper analogues. However, a quick and lasting effect costs that much money.