The medication "Prednisolone" is included in the category of synthetic glucocorticosteroids, is a dehydrogenated analogue of hydrocortisone. The drug has anti-allergic, immunosuppressive, anti-inflammatory activity. When taken orally, the medicine is absorbed very well. For a maximum of two hours, the content of the drug in the plasma reaches the highest level. Metabolism occurs mainly in the liver and partially in the kidney system. Withdrawal from the body is carried out with urine. The drug is found in small quantities in breast milk, crosses the placental barrier.
The medicine "Prednisolone" (tablets). Instructions for use. Indications
The medication is prescribed for rheumatic fever, minor chorea, rheumatic carditis. The tool is recommended for pathologies in the connective tissue of a systemic nature: with dermatomyositis, periarteritis nodosa, scleroderma, lupus erythematosus. Indications include multiple sclerosis, inflammatory processes in the joints of a chronic and acute course. An agent is also prescribed for diseases such as epicondylitis, synovitis, bursitis, Still's syndrome, osteoarthritis (including post-traumatic), shoulder-shoulder periarthritis, psoriatic, juvenile, gouty and rheumatoid arthritis, ankylosing spondylitis. The medicine “Prednisolone” (tablets) recommends the use for asthmatic status, bronchial asthma, interstitial lung pathologies (sarcoidosis of the 2nd and 3rd degree, fibrosis, acute alveolitis), lung cancer.
The drug is prescribed for aspiration (in combination with a specific treatment), Leffler's
eosinophilic pneumonia , berylliosis, tuberculosis (in combination with a specific treatment), hyperplasia, secondary and primary insufficiency in the adrenal glands (including those after their removal). Autoimmune pathologies, hypoglycemic conditions should be attributed to the indications for the prescription of the medication Prednisolone (tablets) (expert reviews confirm this). A drug is also prescribed for hepatitis, allergic diseases of the acute and chronic type, inflammatory lesions of the digestive system,
nephrotic syndrome, diseases of the organs and blood formation system. The medicine "Prednisolone" (tablets), the instructions for use recommends for skin pathologies of an autoimmune and other nature. In particular, a medication is prescribed for exfoliative, herpetiform bullous dermatitis, pemphigus, Lyell syndrome, psoriasis, eczema.
The drug is prescribed for hypercalcemia with oncological pathologies, eye diseases, cerebral edema of the post-traumatic, post-radiation, postoperative period. The medicine is recommended to prevent and eliminate the sensation of nausea or vomiting on the basis of cytostatic therapy, as well as in the prevention of the transplant rejection reaction.
Dosage regimen
The medicine "Prednisolone" (tablets) is recommended for use by mouth, without chewing. As a replacement therapy, the drug is prescribed for 20-30 mg. Maintenance doses - 5-10 mg. Depending on the condition of the patient, the initial amount of the drug can be from 15 to 100 mg. The medicine "Prednisolone" (tablets) is prescribed to children at 1-2 mg / kg. The resulting amount is divided into four to six doses. The maintenance dose per day is 300-600 mcg / kg.