Alcoholism is a problem of many people in our country and not only. It destroys families and the health of the drinker. To help an addicted patient, specialists resort to various drugs. The most popular drug is Medichronal. Instructions for use, reviews and features of the mentioned drugs will be described in the materials of this article.
Form, composition, packaging and description
What is a drug like Medichronal? Reviews of patients say that this medication can be purchased at any pharmacy in the form of light yellow granules without any smell.
This medicine is available in packs. The first package contains such an active component as glucose monohydrate (in the amount of 17.5 g). It also includes an additional ingredient in the form of povidone.
As for package No. 2, it includes glycine (in an amount of 7 g) and sodium formate (in an amount of 3.5 g). Povidone is used as auxiliary components.
What packaging is Medichronal sold in? Instructions for use of detoxification granules are contained in a pack of cardboard. It may contain one set of packages, seven or twenty-one.
Pharmacodynamics
What properties are inherent in the Medichronal medication? The instruction (reviews about this tool will be presented below) reports that this is a combination medicine. It helps to reduce the excessive amount of toxic metabolites of ethyl alcohol (acetic aldehyde) in the human body.
This drug is able to have a detoxifying effect. It also activates metabolic processes and stimulates the biological synthesis of catecholamines, including norepinephrine. This effect of the drug enhances the processes of neuromediation and functional activity of the cerebral cortex, as well as the normalization of the limbic-reticular complex.
What other features does Medichronal have? Instructions for use (reviews of this medicine are very mixed) states that it has a positive effect on the liver. In addition, it significantly improves the patient’s sleep and well-being.
According to experts, the reduction of symptoms of withdrawal symptoms and acute alcohol poisoning occurs approximately 35-37 minutes after taking the granules.
Pharmacokinetics
Where is the absorption of the drug "Medichronal"? Reviews of doctors and patients will not be able to answer the question. To find out, refer to the attached instructions. According to her, glycine is absorbed quite quickly from the intestines. It has high bioavailability, which approaches 100%.
Also, the medication in question quickly penetrates into most fluids, organs and tissues of the body. Under the influence of glycine oxidase, it is transformed in the liver.
As for sodium formate, it is also absorbed from the intestine. After entering the human body, this ingredient immediately reacts with acetaldehyde, as a result of which a conjugate is released, which increases the synthesis of macroergic compounds and is involved in the work of the tricarboxylic acid cycle.
Indications for use
When should you use Medichronal? The instruction for use states that this medication is prescribed in the following cases:
- in order to increase the effectiveness of other methods of therapy for alcoholism;
- with withdrawal symptoms, alcohol poisoning;
- to prevent intoxication;
- for repeated prevention of alcoholism.
Contraindications
Are you aware of the conditions under which Medihronal granules cannot be taken? Instructions, reviews of experienced specialists claim that this drug has practically no contraindications. It is not recommended to appoint it only in the following conditions:
- severe diabetes mellitus;
- hypersensitivity to constituent ingredients;
- arterial hypotension.
The drug "Medichronal": instructions for use
Reviews of the tool in question will be described below.
This medication is taken only after a meal. The contents of two sachets are pre-dissolved in 200 ml of water.
A single dose of this medicine is considered 28.5 g, that is, the sum of the masses of the granules of two packets.
In order to enhance the taste of the drug as a solvent, it is allowed to use not ordinary water, but any non-carbonated drinks.
So in what dosage Medichronal granules are prescribed? The instruction reports that for the relief of withdrawal symptoms and acute alcohol poisoning, the patient is prescribed 28.5 g of the drug after 12 hours on the first day, and in the second and third - 28.5 g once a day.
When the drug is combined with other agents (in the treatment of chronic alcoholism or as a second prophylaxis), Medichronal is recommended to take 28.5 g once a day for a week. As a rule, such courses are held three times with interruptions of three days.
To prevent relapse, 6 weeks after therapy, experts advise to undergo a repeated monthly course of treatment. Such preventive cycles are preferably carried out for 1-2 weeks 1-3 times a year.
In order to prevent intoxication, the patient must take a single dose of the medication 30 minutes before the intended use of alcoholic beverages.
Adverse reactions
The medication in question can cause the following side effects:
- From the digestive tract, nausea may occur.
- On the part of the NS, the patient often has a headache, decreased concentration, irritability, and excessive tension.
- Allergic reactions in the form of itching, rash on the body and urticaria can also occur.
Overdose cases
When taking high doses of detoxification granules, the patient may experience disturbances in the digestive system, such as diarrhea, bloating and nausea. Adverse reactions may also intensify. In this case, symptomatic treatment should be carried out.
Reviews about the drug
Now you know what the Medichronal medicine is. Instructions for use, reviews are described in this article.
According to experts, patients' reports about Medihronal do not always correspond to the image of the drug that was formed in the television commercial. Therefore, many doctors recommend using this medication only in combination with other medicines.
It should also be noted that the majority of patients who took this drug before consuming alcoholic beverages claim that it is ineffective and contributes only to sleeping pills.