The medicine "Perfalgan", the price of which is from 380 rubles and above, belongs to the group of analgesic non-narcotic drugs. The active substance is paracetamol. The mechanism of action of the drug is determined by the ability to block a number of enzymes, acting mainly in the central nervous system, by the effect on thermoregulatory and pain centers. This explains the almost absolute absence of anti-inflammatory activity. The medication does not negatively affect the gastrointestinal mucosa and the process of water-salt metabolism.
Means "Perfalgan." Instructions for use. Appointment
The medication is recommended for febrile syndrome accompanying infectious pathologies. The medicine is prescribed to eliminate the pain of a moderate and weak course. Indications include algodismenorea, migraine, arthralgia, neuralgia. Prescribe the drug for headaches or toothaches, with myalgia.
Contraindications
The Perfalgan remedy (instructions for use clearly indicates this) can not be prescribed to patients up to a month of life, with hypersensitivity, hyperbilirubinemia (benign type), Gilbert syndrome, kidney and liver failure, alcoholic liver damage. Contraindications include hepatitis of a viral nature, pregnancy, old age, diabetes mellitus (for the suspended form). The medicine “Perfalgan” is not prescribed (the instructions for use confirm this) during lactation, with a deficiency of glucose-6-phosphate dehydrogenase.
Side effects
Against the background of drug therapy, skin rash, irritation, itching of the integument or mucous membranes, orientation disorder, psychomotor agitation, angioedema can be noted. Negative reactions include hepatonecrosis (this effect is dose-dependent), erythema multiforme exudative, epigastric pain, hypoglycemia (to hypoglycemic coma). The drug can cause heart pain, shortness of breath, cyanosis, anemia (including hemolytic). When taken in large doses, papillary necrosis, interstitial nephritis, renal colic and other nephrotoxic manifestations are observed.
The medicine "Perfalgan." Instructions for use
They drink medicine with a large volume of liquid. It is recommended to take the medicine after meals (an hour or two). Patients weighing more than forty kilograms over 12 years of age are prescribed 500 mg once. The maximum amount of medication at one time is 1 gram. Frequency of use per day - no more than four times. The duration of treatment is no more than five or seven days. If the patient has disorders of renal or hepatic function, Gilbert's syndrome, as well as elderly patients, the dosage is reduced or the interval between doses is increased. The dosage scheme for children is set by a specialist personally.
The medicine "Perfalgan." Instruction Additional guidance
Against the background of taking the drug, there is probably a distortion of laboratory tests when determining the plasma level of uric acid and glucose. With prolonged therapy, the state of the blood picture (peripheral), as well as liver functions, should be monitored.