How effective is a drug like Lindinet 30? Reviews of gynecologists about the mentioned medicine are presented in this article. It also considers the detailed instructions for this remedy, its indications, side effects, and more.
Form of the drug, its description and composition
What is a medicine like Lindinet 30? Reviews of gynecologists report that this medication is made in the form of yellowish, round and biconvex tablets, without any inscriptions.
The active components of the drug in question are gestodene and ethinyl estradiol. The tablets also include auxiliary elements such as lactose monohydrate, sodium calcium edetate, starch from corn, magnesium stearate, povidone and colloidal silicon dioxide.
Drug action
How does the drug "Lindinet 30"? Reviews of gynecologists, instructions report that this tool is an oral monophasic contraceptive that can inhibit the secretion of pituitary hormones (gonadotropic). The contraceptive properties of this medication are associated with several mechanisms.
Ethinyl estradiol acts as the estrogen component of this medication. This is a synthetic analogue of the hormone estradiol (follicular), which, together with the corpus luteum hormone, takes part in the regulation of the monthly cycle.
As for the progestogen component, gestodene, which is a derivative of 19-nortestosterone, is attributed to it. In its selectivity and potency, it surpasses not only progesterone (or the so-called natural hormone of the corpus luteum), but also other synthetic progestogens, including levonorgestrel.
Due to the high activity, the mentioned component is used only in reduced doses, in which it will not be able to exhibit androgenic properties and will not have any effect on carbohydrate and lipid metabolism.
Features of the tool
What is remarkable about the Lindinet 30 medicine? Reviews of gynecologists say that in addition to the central and peripheral mechanisms that prevent egg maturation, the contraceptive properties of this medication are also due to the fact that it reduces the sensitivity of the endometrium to blastocyst. Also, taking this agent increases the viscosity of the mucus that is in the cervix, which contributes to sperm obstruction.
Other properties
It should be noted that in addition to contraceptive properties, the drug in question also has a therapeutic effect. It normalizes the menstrual cycle and prevents the development of a number of gynecological diseases, including tumor nature.
Kinetic ability
How is the absorption of a drug such as Lindinet 30? The instruction indicates that after taking the medicine, its main substances are rapidly absorbed from the digestive tract.
With a single dose of the drug, its peak concentration in the blood is reached after 1 hour. The bioavailability of this medicine is 98.9%.
Gestoden binds to globulin and albumin. It undergoes biotransformation in the liver and is excreted from the body only in the form of derivatives along with feces and urine.
As for ethinyl estradiol, it undergoes aromatic hydroxylation. In this case, hydroxylated and methylated metabolites are formed. Ethinyl estradiol is excreted only in the form of derivatives, together with bile and urine in a ratio of 3: 2.
Indications for appointment
What is the use of the drug "Lindinet 30"? Reviews of gynecologists say that this is a highly effective contraceptive. It is taken by women of reproductive age in order to prevent an unwanted pregnancy.
Prohibitions for receiving funds
Under what conditions can not use the drug "Lindinet 30"? The use of this medication is contraindicated:
- in the presence of thrombosis (including transient ischemic attack and angina pectoris);
- severe and multiple risk factors for arterial or venous thrombosis (including complicated damage to the valves of the heart muscle, atrial fibrillation, coronary artery disease of blood vessels or the brain, arterial hypertension);
- migraines with neurological focal symptoms;
- venous thromboembolism;
- diabetes mellitus (with angiopathy);
- arterial or venous thrombosis or thromboembolism (including heart attack, deep vein thrombosis of the leg, stroke, pulmonary embolism);
- surgical intervention with prolonged immobilization;
- pancreatitis, which is accompanied by severe hypertriglyceridemia;
- dyslipidemia;
- jaundice when using corticosteroids;
- severe liver diseases, cholestatic jaundice, hepatitis;
- gallstone disease;
- liver tumors;
- Gilbert syndrome, Dubin-Johnson syndrome, Rotor syndrome;
- severe itching, otosclerosis or its progression with previous gestation or taking corticosteroids;
- vaginal bleeding of unknown origin;
- malignant hormone-dependent neoplasms of the mammary glands and genitals;
- smoking at the age of 35 years;
- hypersensitivity to the elements of the drug.
Also, the drug is forbidden to take during pregnancy and during lactation.
Medication "Lindinet 30": instructions for use
The medicine in question is prescribed one tablet per day for 21 days, at the same time. After taking the last dosage, take a week break. Further, the use of the drug is resumed. The first pill of this medication should be taken from the first to the fifth day of the monthly cycle.
If the patient switches to the drug “Lindinet 30” from a different oral contraceptive, then the 1st tablet should be taken immediately after taking the last dosage of another hormonal agent.
After an abortion at the very beginning of pregnancy, the use of the medication can begin immediately after the operation. In this case, there is no need to use other methods of contraception.
After childbirth or abortion in the second trimester, medication can be started already on the 22-28th day. In this case, in the first week it is necessary to use other contraceptives.
If you skip taking the medicine, you should take the pill as soon as possible. If the interval between doses of the drug was less than 12 hours, then the contraceptive effect does not decrease. In this case, you do not need to use other methods of contraception.
If the interval was more than 12 hours, then the contraceptive effect of the drug may decrease. In this situation, the next week it is necessary to apply additional methods of contraception.
If diarrhea and vomiting begin within 4 hours after using the medication, then its contraceptive effect may decrease. In such cases, follow the directions for skipping pills.
To speed up the onset of menstruation, you should shorten the break in taking the medication. To delay the onset of menstruation, medication should be continued without a week break.
Adverse reactions
What side effects can Lindinet 30 cause? The reviews of gynecologists (in case of myoma this medicine can be taken only on the recommendation of a doctor), they say that taking the medication in question should be immediately canceled if it causes the following reactions:
- arterial hypertension, hearing loss due to otosclerosis, venous and arterial thromboembolism;
- hemolytic-uremic syndrome, venous or arterial thromboembolism of mesenteric, hepatic, retinal and renal veins and arteries;
- porphyria, Sydenham chorea, exacerbation of reactive lupus erythematosus.
Other side effects of this drug that do not require its withdrawal are the following:
- migraine, candidiasis, acyclic bleeding from the vagina, galactorrhea, amenorrhea after drug withdrawal, pain, changes in the vaginal mucus, enlargement of the mammary glands, the development of inflammation in the vagina, tension;
- ulcerative colitis, headache, liver adenoma, epigastric pain, cholelithiasis, nausea, hepatitis, vomiting, exacerbation of jaundice, Crohn's disease;
- exudative erythema, depression, erythema nodosum, chloasma, rash, hair loss;
- increased sensitivity of the cornea, hearing loss;
- mood lability, decreased carbohydrate tolerance, water retention in the body, hyperglycemia, changes in body weight, increased TG levels;
- allergy.
Reviews of specialists
Now you know what a tool like Lindinet 30 is for. The instructions and purpose of this medication were presented above. What do gynecologists say about him? Most experts leave exclusively positive reviews about this medication. They argue that such an oral contraceptive effectively helps solve the issue of unwanted pregnancy. At the same time, doctors stipulate that even when taking the correct dosages of the drug and observing a strict scheme, the weight of patients may unreasonably increase, which, of course, cannot but upset them.
Gynecologists also report that in addition to their main purpose, the considered birth control pills are actively used as a therapeutic agent in gynecological pathologies, including functional disorders of the monthly cycle.
Thanks to a carefully developed formula, as well as a thoughtful scheme for taking a contraceptive, you can easily achieve the desired results for a long time. In this case, gynecologists say that Lindinet 30 tablets can cause adverse reactions. In this regard, before taking them, you should definitely seek additional advice from an experienced specialist.