The drug "Bactrim" is a combined antimicrobial agent with a wide spectrum of action, the active substances of which are trimethoprim and sulfamethoxazole.
It is produced in such forms: syrup; suspension for internal use, separately for adults and for children; tablets, separately for children and adults; coated tablets; concentrate used for the preparation of infusion solutions.
The pharmacological effect of the drug "Bactrim" instructions for its use are described as follows: the active substances contained in this medicine disrupt intracellular metabolism in the bacterial cell. The bactericidal activity of this medication is manifested against various types of streptococci, staphylococci, Nisseria, Escherichia, salmonella, cholera vibrios, anthrax bacilli, bordetellae, enterococci, listeria, nocardia, protea, chlamydia, toxoplasma, morganoella, and other mushrooms, plasmoids.
The duration of the therapeutic effect of the dose is seven hours.
Indications for taking the drug "Bactrim", the instruction lists the following: infections of the genitourinary sphere (cystitis, urethritis, pyelitis, pyelonephritis, prostatitis, epididymitis, male and female gonorrhea, venereal lymphogranuloma, mild chancre, inguinal granuloma), infections of the respiratory system (both acute and and chronic bronchitis, bronchiectasis, bronchopneumonia, croupous and pneumocystis pneumonia), ear, nose and throat infections (sinusitis, otitis media, laryngitis, tonsillitis), scarlet fever, digestive tract infections (paratyphoid, abdominal typhoid, cholera, salmonella carriage, dysentery, cholera, cholangitis, cholecystitis, gastroenteritis that caused enterotoxic strains of Escherichia coli), infectious lesions of soft tissues and skin (furunculosis, acne, pyoderma), acute and chronic forms of osteomyelitis, various wound infections infections, acute brucellosis, South American blastomycosis, toxoplasmosis (as part of complex therapy), malaria.
Contraindications to the use of this drug are: hypersensitivity to the components of this drug and to all sulfonamides in general, renal and / or liver failure, aplastic anemia, anemia associated with vitamin B12 deficiency, leukopenia, glucose-6-phosphate dehydrogenase deficiency, agranulocytosis, breast-feeding , pregnancy, pneumocystis pneumonia, for i / m administration - age up to six years, children with hyperbilirubinemia.
To prescribe with caution, the drug "Bactrim" recommends the use of it for bronchial asthma, various pathologies of the thyroid gland, folic acid deficiency in the body.
Side effects of this medication are:
- From the nervous system - from headache to aseptic meningitis and peripheral neuritis.
- From the digestive tract - from nausea to hepatonecrosis and pseudomembranous enterocolitis.
- From the hematopoietic system - from leukopenia to megaloblastic anemia.
- From the urinary organs - from polyuria to anuria.
- Also arthralgia, myalgia, a variety of allergic manifestations.
Local reactions to the administration of the drug "Bactrim" instructions for use include the following: thrombophlebitis at the site of intravenous administration and soreness at the site of intramuscular injection.
In case of an overdose, gastric lavage, intramuscular administration of five to fifteen mg per day of calcium folate, up to hemodialysis.
Dosage and methods of use of the drug "Bactrim" instructions for its use include the following:
- Tablets are prescribed for children from the age of twelve and adults nine hundred sixty milligrams once a day or four hundred eighty milligrams twice a day, if the infection is severe, then four hundred eighty milligrams three times a day. Children from one to three years old - one hundred twenty milligrams twice, from two to six years old - from one hundred twenty to two hundred forty milligrams twice, from six to twelve - from two hundred forty to four hundred eighty milligrams twice.
- Suspension is prescribed for children aged three to six months - one hundred twenty milligrams twice, from seven months to three years old - from one hundred twenty to two hundred forty milligrams twice, from four to six years - from two hundred forty milligrams twice and up to four hundred eighty milligrams twice, from seven to twelve years - four hundred eighty milligrams twice, for adults and children after twelve years - nine hundred and sixty ml twice.
- The drug "Bactrim Syrup" is prescribed for children from one to two years, one hundred twenty ml twice, from two to six years - one hundred eighty and up to two hundred and forty milligrams twice, from six to twelve years - two hundred and forty and up to four hundred eighty milligrams twice.
- Parenterally intramuscularly - for adults and children over twelve years old - four hundred eighty milligrams twice, for children from six to twelve - two hundred forty milligrams twice. Parenteral intravenously - for children over twelve and adults - from nine hundred sixty to one thousand nine hundred twenty twenty milligrams twice, for children from six to twelve - four hundred eighty milligrams twice, from six months to five years - two hundred forty milligrams twice, from six weeks to five months - one hundred twenty milligrams twice.
The duration of therapy is set by the attending physician.