Amoxiclav is one of the drugs used to treat infections caused by bacteria. Instructions for use of this drug indicate its antibacterial pharmacological effect, and quite a wide range.
Amoxiclav is a modern antibiotic. The active ingredients of this medication are amoxicillin (semisynthetic penicillin) and clavulanic acid (a β-lactamase inhibitor), complementing each other in combination, since they are similar in their pharmacokinetic parameters. Amoxicillin is present in the Amoxiclav preparation (instructions for use provide information on this) as trihydrate, clavulanic acid - like potassium clavulanate. And if the first active substance in one tablet of the drug is 500 mg, then the acid in it contains 125 mg. Among the excipients of the drug are talc, crospovidone, silicon colloidal dioxide, MCC, magnesium stearate, croscarmellose sodium. The package contains 15 tablets of Amoxiclav medicine. They are oval in shape, covered with a shell of a film of almost white color, biconvex.
Both ingredients of Amoxiclav are well distributed in tissues such as the uterus, lungs, ovaries, middle ear, as well as in pleural and peritoneal fluids. In addition, amoxicillin has the ability to penetrate the liver, gall bladder, saliva, synovial fluid, secretion of the paranasal sinuses, prostate gland, muscle tissue, bronchial secretion, tonsils. Using clavulanic acid, which has a weak antibacterial activity, the stability of amoxicillin to the action of β-lactamases is ensured. They are produced by microorganisms (aerobic gram-negative and gram-positive bacteria, anaerobes, gram-positive and gram-negative, etc.).
The drug "Amoxiclav" instructions for use advises to take in the treatment of infectious and inflammatory diseases that are caused by microorganisms that are most sensitive to the active substances of the drug. These are infections:
- ENT organs and respiratory system, its upper sections (such as pharyngeal abscess, chronic sinusitis, pharyngitis, otitis media (chronic and acute), tonsillitis) ;
- respiratory system of the lower sections (including bronchitis (acute and chronic) and pneumonia);
- urinary system;
- gynecological;
- soft tissues, skin (including animal and human bites);
- connective and bone tissue;
- biliary tract;
- odontogenic.
Since this medicine is available in the form of tablets, powders, drops, suspensions and as a solution for intravenous injection, the dosage in them is different. So, Amoxiclav 250 tablets, the instructions for use are recommended for adults to take one 3 times a day, and children younger than 14 years old should choose a suspension (1.5-2 teaspoons - it all depends on the age of the child) or drops that give per day 3 times 0.75-1.25 mg. If the doctor prescribed amoxiclav intravenously (instructions for use 1000 mg indicates), then the medicine is administered slowly every six to eight hours for 1.2 mg for adults and children over 12 years of age. If the child is not 12, then at the rate of 30 milligrams per kilogram of weight.
Pharmaceutical companies produce analogues of Amoxiclav, similar in composition and effect. These are the preparations “Klavocin”, “Moksiklav”, “Amoklan”, “Kuram”, “Augmentin”, “Klavunat”, “Amoklavin”, etc.
Keep a drug such as Amoxiclav in a place inaccessible to children's pens and so that the air temperature does not exceed 25 degrees.
Are there any contraindications and side effects of Amoxiclav? Instructions for use about this have information. So, it is not recommended to take this medication for those patients who have an increased susceptibility to antibiotics included in the groups of cephalosporins and penicillins, to components of amoxiclav, who have impaired liver function, etc. In any case, carefully read the instructions before using the medicine.
When taking amoxiclav, side effects from the gastrointestinal system (diarrhea, vomiting, nausea, loss of appetite) also occur.
Take care of your health!