"Pyobacteriophage complex" - an antibacterial drug that is a bacteriophage.
The drug is available in the form of solutions for oral administration, as well as for local external use and is a transparent, slightly yellow liquid, but its color varies from light to dark yellow, sometimes with a pronounced greenish tint.
This medicine is packaged in 20 ml vials placed in cardboard boxes of 8 pieces, as well as in 100 ml vials, 1 piece in a pack.
The composition of the medication
The active substance, which is part of 1 ml of this solution, is sterile-purified filtrates of bacterial phagolysates Streptococcus, Proteus mirabilis, Enterococcus, enteropathogenic Escherichia coli, Staphylococcus and Proteus vulgaris, Klebsiella pneumoniae, Klebsiella oxytoca and Pseudosaonas.
As additional components, preservatives are used: 8-hydroxyquinoline sulfate or 8-hydroxyquinoline sulfate monohydrate.
Pharmacological properties of the drug
"Pyobacteriophage complex" causes the lysis of the following types of bacteria:
- enteropathogenic Escherichia coli;
- Staphylococcus;
- Proteus vulgaris;
- Pseudomonas aeruginosa;
- Klebsiella pneumonia;
- Streptococcus, Enterococcus;
- Proteus mirabilis;
- Klebsiella oxytoca.
Indications for use
According to the instructions, "Pyobacteriophage complex" can be used for the prevention and treatment of a variety of purulent, inflammatory and intestinal diseases that are caused by the action of pathological microorganisms such as enterococci, streptococci, staphylococci, Pseudomonas aeruginosa, Klebsiella, Proteus, Escherichia coli of various serogroups.
Thus, the use of the drug is indicated when the following pathological conditions occur:
- The occurrence of enteric infections - dysbiosis, gastroenterocolitis, cholecystitis.
- In diseases of the ENT organs, as well as the upper respiratory tract and lungs, inflammatory processes in the middle ear and sinuses, laryngitis, pharyngitis, tonsillitis, tracheitis, bronchitis, pleurisy, pneumonia.
- A variety of urinary tract infections - cystitis, urethritis, pyelonephritis.
- When infected with genital infections - salpingoophoritis, endometritis, colpitis.
- In the event of generalized forms of various septic diseases - conjunctivitis, keratoconjunctivitis, iridocyclitis, purulent corneal ulcers.
- For surgical infections - carbuncles, boils, phlegmon, abscesses, felon, hydradenitis, burns, suppuration of wounds, osteomyelitis, bursitis, mastitis, paraproctitis.
- With the occurrence of purulent-inflammatory diseases in infants - conjunctivitis, omphalitis, pyoderma, gastroenterocolitis, sepsis, etc.
- With some other diseases that are provoked by the above pathogenic microorganisms.
The use of medication for prevention
For preventive purposes, this drug can be used to prevent the occurrence of a variety of nosocomial infections, for the treatment of fresh postoperative wounds. In addition, the use of the drug "Pyobacteriophage complex" may be appropriate in cases of any superficial skin lesions in adults and children as a strong antiseptic.
Contraindications
A medication is contraindicated in the presence of symptoms of hypersensitivity to its main or auxiliary components. In other cases, it can be used.
Mode of application
How to take "Pyobacteriophage complex"?
It is used in different ways, depending on the site of infection - in the form of instillations, rinses, rinses and the introduction of tampons moistened in solution during pathological processes that occur in the ENT organs. In this case, the drug is used in 2-10 ml several times a day. Tampons moistened in a medicinal solution are left, as a rule, for 1 hour.
When instilled into the conjunctival sac - with the development of conjunctivitis and keratoconjunctivitis - 2 drops 5 times a day. With the formation of purulent ulcers on the cornea - 5 drops, with the development of purulent iridocyclitis - 8 drops every 2 hours, while combining local treatment with a medication and oral administration. When using various irrigation and lotions, “Pyobacteriophage complex” is used in an amount of up to 150 ml, which depends on the size of the foci of inflammation.
In case of abscesses, the drug solution is injected directly into the cavity of the focus after cleansing it of purulent contents, and this is done by puncture in an amount approximately equal to the volume of the removed pus.
With osteomyelitis, the medication is used by infusion into the wound after the necessary surgical treatment in a volume of 10 ml. To rinse the mouth with the development of stomatitis and chronic periodontitis: 20 ml several times a day. It is also possible to introduce Turund soaked with a medicinal solution into periodontal pockets.
The use of "Pyobacteriophage complex" is possible in the form of enemas for the development of intestinal dysbiosis, as well as in intestinal forms of pathologies of internal organs.
For the treatment and prevention of urinary tract infections, drainage is used in the cavity of the renal pelvis or bladder - the drug is administered through a nephrostomy or cystostomy 2 times a day in a volume of 20-50 ml.
Treatment of pathological processes characterized by the formation of pus and the occurrence of inflammation is carried out, as a rule, both locally and orally. The duration of treatment procedures depends on the nature of the disease and its degree and is usually from 7 to 20 days.
The purpose of the medication does not exclude the use of other antibacterial agents. This is confirmed by the instructions for use to "Pyobacteriophage complex."
Side effects
Until now, there have been no cases of adverse reactions with the use of the drug.
No cases of drug overdose have been reported.
special instructions
The main condition for the effectiveness of therapy with this medication is the early determination of the phage sensitivity of pathogens and the use of "Pyobacteriophage" in the early stages of the disease. Before each use, the vial with the drug solution must be shaken. Before opening it, you need to disinfect your hands, treat the cap of the bottle with alcohol solutions. These measures are necessary so that bacteria do not enter the vial, as this can cause clouding of the solution and unsuitability of the drug. Keep the drug in the refrigerator.
Differences "Pyobacteriophage" complex and polyvalent
In the treatment of infectious and inflammatory pathologies, the causative agents of which are pathogenic microbes, use solutions with sterile phagolysates of these microorganisms in the composition. In the pharmacy you can usually find two types of such funds: "Piobacteriophage" multivalent and complex. There is no difference between them at first glance, so the wrong drug is often purchased.
Distinctive features can be found in the instructions, in particular with a careful study of their composition.
The solution of the complex agent still additionally contains a sterile enterococcal phagolysate.
There is no significant difference between the action of the polyvalent and complex "Pyobacteriophage". The list of indications they have is completely the same. Although there is one difference, if the pathology is caused by enterococci, the multivalent solution will be ineffective.
Which is better to buy, you decide. But you should take into account the nuance. Before prescribing any medication with antimicrobial action, an analysis must be carried out with the help of which it is possible to identify the causative agents of the disease and their sensitivity to the drugs.
So, if enterococci provoked an ailment, it is better to acquire a complex solution.
"Pyobacteriophage complex": reviews
For children, this tool is very well suited. This is confirmed by numerous reviews. It is really effective, it helps quickly. People note that it rarely causes adverse reactions only if there is an individual intolerance.