What is the purpose of prescribed medication "Serrata" (tablets)? Instructions and indications for the use of the drug will be presented in this article. Also in it you will find information on whether there are contraindications for this remedy, what side effects may occur against the background of its prima, what doctors and patients are talking about it.
Packaging, composition
What substances do Serrata tablets contain? Instructions for use informs that the active element of this agent is serratiopeptidase. It also contains additional components in the form of sodium starch glycolate, light magnesium carbonate, lactose monohydrate, magnesium stearate and corn starch.
You can buy a medicine with an enteric coating in cell packages, which are placed in cardboard boxes along with the instructions.
Pharmacology
What are the effects of Serrata (tablets)? The instruction says that this medication can have anti-inflammatory, fibrinolytic and decongestant effects.
Serratiopeptidase is an enzyme that is extracted from an intestinal bacterium such as Serratia E15. It has a non-pathogenic nature and exhibits a proteolytic effect.
The substances that make up this medication quickly break down bradykinin, fibrin, and other inflammatory mediators. They also exhibit anti-inflammatory and decongestant effects. This effect is due to the release of painful amines, which are contained in inflamed tissues.
Features of the medication
How do Serrat tablets work? The use of this medication helps to lyse necrotic tissues and their decay products. Its active substance reduces hyperemia, and also catalyzes the activity and absorption of various antibiotics.
It should be noted that this drug is able to reduce the viscosity of saliva and thin the nasal discharge, facilitating their excretion.
Tablet properties
What are the properties of the drug "Serrata" (tablets)? Instructions, reviews indicate that due to the breakdown of bradykinin, serotonin and histamine, the active substance of the agent in question reduces the permeability of capillaries and reduces their dilatation. In addition, it leads to inhibition of plasmin blockers, thereby improving their fibrinolytic effect.
Kinetic indicators
Where is the drug "Serrata" (tablets) absorbed? Reviews of experts say that the absorption of this medicine occurs in the intestine. It should also be noted that the substances that make up this medication are enclosed in a special enteric coating. Therefore, tablets do not break down in the stomach.
In the blood, the maximum amount of the active component of this medicine is detected after an hour. As a rule, this drug is excreted through the kidneys.
Indications
When is Serrata (tablets) prescribed? Reviews of doctors report that taking this medication should be carried out only after consulting a doctor.
This medication is prescribed in the treatment of various diseases.
- In otolaryngology: with sinusitis, otitis media and other inflammations, which are accompanied by increased mucus formation and difficult separation of sputum. Also, this medication is used to improve the absorption of antibiotics.
- In surgery and traumatology: for fractures, sprains, dislocations and other injuries. In addition, such tablets are used for edema and for the prophylactic purpose of probable transplant rejection.
- In dermatology: with acute dermatoses occurring with pain.
- In plastic surgery: to reduce swelling after surgery and increase microcirculation in the prevention of probable transplant rejection.
Drug bans
When should you not use Serrata (tablets)? Instructions, reviews indicate contraindications such as:
- hypersensitivity to the constituent substances of the drug;
- pathological conditions that lead to a violation of blood coagulation and an increased risk of bleeding.
The drug "Serrata" (tablets): instructions
The medication in question is intended for oral use. He is prescribed one tablet a day in three divided doses. Food does not affect the absorption and effectiveness of the drug.
Enteric tablets should be swallowed whole.
The adjustment of the daily dose of this medicine depends on the severity and type of disease. A narrow specialist should determine the minimum effective dosage, as well as the duration of the medication, based on the specific situation.
Adverse reactions
What side effects can Serrat tablets cause, the analogues of which are listed below? According to the instructions, in rare cases, this medication contributes to impaired stool, as well as the appearance of vomiting, nausea and abdominal pain.
Patients predisposed to bleeding, while taking this drug, can observe frequent nosebleeds and blood in the sputum.
Sometimes the drug in question provokes the appearance of allergic reactions. These include the following: itching or rashes on the skin, as well as urticaria.
Overdose cases
Exceeding the recommended doses of the drug "Serrata" can provoke an increase in adverse reactions. In some cases, an overdose can cause internal bleeding.
If such pathological conditions occur, you should refuse to take the medicine and conduct symptomatic therapy.
Compatibility with other medicines
The combination of anticoagulants and serratiopeptidase can lead to increased action of the former. If these funds should be taken simultaneously, then the patient should be under the strict supervision of a doctor, who, if necessary, will be able to adjust the dosage of the anticoagulant.
Recommendations for the use of the drug
What should I know before taking Serrata medication (tablets)? The instructions accompanying this medicine are required to be read. It says that this drug affects blood coagulation processes. In this regard, it should be used with extreme caution, especially in combination with anticoagulants, in pathologies of blood coagulation and the patient's predisposition to bleeding.
A patient who has been diagnosed with kidney and liver disease and is taking Serrata should be monitored regularly by a specialist.
Reviews, price and analogues of the drug
Analogues of the drug "Serrata" are such funds as "Sroks", "Wobenzym", "Fibrinase", "Serta", "Phlogenzim." The listed medicines are also combination medicines that are used in various fields of medicine.
How much is the drug in question? The price of this medicine in the amount of 10 tablets is 110-120 rubles.
As for the reviews about this tool, they are positive. Almost all patients are satisfied with the results of treatment. They report the high effectiveness of this drug, including when used concurrently with antibiotic agents.
Doctors also claim that this is a reliable combination medication that can be used to treat inflammatory processes.