The drug is available in pale yellow tablets, which are coated. The Novinet tablets, the instruction of which is presented here, are a biconvex disk with the letter “P” marked on one side and the letters “RG” on the other.
Structure
Active substances:
- desogestrel - 150 mcg (in 1 tablet)
- ethinyl estradiol - 20 mcg (in 1 tablet)
Excipients:
- anhydrous colloidal silicon dioxide;
- potato starch;
- quinoline yellow;
- povidone;
- alpha tocopherol;
- stearic acid;
- lactose monohydrate;
- magnesium stearate.
pharmachologic effect
The drug "Novinet" is a complex hormonal contraceptive that must be taken orally, containing a combination of estrogen and gestagen. Novinet inhibits the release of gonadotropic hormones by its action.
One of the active ingredients - desogestrel - inhibits the synthesis of FSH and LH in the pituitary gland and blocks ovulation, preventing the maturation of follicles.
Ethinyl estradiol, together with the hormone produced by the corpus luteum, is involved in the organization of the menstrual cycle, in addition, it interferes with fertilization, preventing the eggs from ripening.
Indications
It is an oral contraceptive.
Side effects of the drug "Novinet"
The instruction includes both side effects of the drug, in which it is necessary to stop taking it, and those actions that can pass after some time, or be treated symptomatically.
Possible side effects from the use of the drug from the cardiovascular system:
- stroke;
- increase in blood pressure;
- pulmonary embolism;
- myocardial infarction.
Possible side effects from the use of the drug from the gastrointestinal tract:
- cholelithiasis;
- vomiting
- nausea;
- cholestatic jaundice;
- hepatocellular adenoma;
- gastralgia
Possible side effects from the use of the drug from the skin and mucous membranes:
- rash;
- erythema nodosum;
- chloasma;
- generalized itching.
Possible side effects from the use of the drug from the genitourinary system:
- amenorrhea (begins after discontinuation of the drug);
- intermenstrual bleeding;
- change in libido;
- sore menstruation;
- a change in the nature of the vaginal mucus;
- vaginal candidiasis;
- aggravation of endometriosis;
- an increase in uterine fibroids;
- milk excretion.
Possible side effects from the use of the drug from the side of metabolism:
- body hydration;
- decrease in carbohydrate tolerance;
- weight change.
Possible side effects from the use of the drug from the organs of vision:
- conjunctivitis;
- swelling of the eyelids;
- flicker before the eyes;
- visual impairment;
- increased corneal sensitivity (applies only to contact lens wearers).
Possible side effects from the use of the drug from the central nervous system:
- depression;
- headache;
- hearing loss;
- migraine;
- lability of mood.
Other possible side effects:
- exacerbation of lupus erythematosus;
- Sydenham chorea (which goes away after the drug is discontinued).
Contraindications of the drug "Novinet"
The instruction includes a basic list of contraindications for the use of the drug.
- family form hyperlipidemia;
- pregnancy;
- thromboembolism;
- arterial hypertension;
- endometrial hyperplasia;
- Ischemic heart disease;
- myocarditis;
- decompensated heart defects;
- liver disease
- diabetic angiopathy;
- genital bleeding;
- genital herpes;
- severe skin itching;
- endometriosis;
- endometrial cancer;
- breast fibroadenoma.
Medicinal interaction of the drug "Novinet"
The instruction, reviews of the drug from the turnover according to which were not made, states that changes in the nature and rhythm of menstruation, as well as a weakening of the contraceptive effect of novinet, can occur if it is combined with the following drugs - phenobarbital derivatives, antispasmodics, chloramphenicol, penicillin, neomycin, isoniazid, rifampicin , ampicillin, tetracycline, phenylbutazone, carbamazepine and many others.