In the article, we will consider how to take "Tsifran" with angina. In adults, it is an infectious-allergic process in which local changes affect the lymphoid pharyngeal ring, in most cases, tonsils. The course of this disease is characterized by fever, general intoxication syndrome, soreness and enlargement of the cervical lymph nodes, sore throat when swallowing. On examination, hypertrophy and hyperemia of the palatine arches and tonsils are detected, sometimes purulent plaque may occur.
In otolaryngology, three types of angina are distinguished:
- Primary (other names - banal, simple or ordinary). An acute inflammatory disease of a bacterial nature. Signs of a general infection and symptoms of damage to the lymphoid tissue of the pharyngeal ring are characteristic.
- Secondary tonsillitis (symptomatic). It is one of the manifestations of another disease. The defeat of the tonsils may be accompanied by some acute infectious diseases (infectious mononucleosis, diphtheria, scarlet fever), diseases of the blood system (leukemia, alimentary toxic aleukia, agranulocytosis).
- Specific tonsillitis. The disease is caused by a specific infectious agent (fungi, spirochete, etc.).
About 85 percent of all primary tonsillitis is caused by ß-hemolytic streptococcus of group A. In other cases, pneumococcus, Staphylococcus aureus, or mixed flora acts as a pathogen. Primary angina in prevalence is in second place after acute respiratory viral infections. It develops more often in spring and autumn. It affects mainly children and adults under the age of 35 years.
An otolaryngologist diagnoses angina on the basis of data from bacteriological culture from the throat and pharyngoscopy. Antibiotics are prescribed and local treatment (lacunae washing, gargling, treatment of tonsils with drugs), physiotherapy.
"Tsifran" with angina
With angina of all forms, including purulent, antibacterial drugs are prescribed, one of which is “Tsifran”. This is an antimicrobial agent with a wide spectrum of action from the category of fluoroquinolones, which has a pronounced bactericidal effect, inhibits DNA gyrase and inhibits DNA synthesis of bacterial cells.
“Tsifran” is highly active in adults with angina in relation to the bulk of gram-negative bacteria, which include: Pseudomonas aeruginosa, Escherichia coli, Haemophilus influenzae, Shigella spp., Neisseria meningitidis, Salmonella spp., Neisseria gonorrhoeae.
In addition, this antibiotic effectively destroys Staphylococcus spp. (including strains that produce and do not produce penicillinase, as well as strains resistant to methicillin), some strains of Enterococcus spp., Legionella spp., Campylobacter spp., Mycoplasma spp., Mycobacterium spp, Chlamydia spp.
Ciprofloxacin has destructive activity against bacteria that produce β-lactamases. Resistant to Ureaplasma urealyticum, Nocardia asteroides and Clostridium difficile.
Release Forms
The drug "Tsifran" is available in the following forms:
- tablets in a dosage of 250 or 500 mg;
- solution for infusion at a dose of 2 mg.
Read more about the dosage of "Tsifran" with sore throat in adults below.
Pharmacological properties
The medicine is based on the active element - ciprofloxacin. The basis of its therapeutic effect is the principle of inhibition of bacterial enzymes and impaired synthesis of their DNA. In addition, the medication is able to increase the permeability of the cell membranes of harmful microorganisms and exert a bactericidal effect on them. The bacteria are susceptible to the action of the drug both at the stage of reproduction and those that are at rest.
Indications for use
The drug "Tsifran" is prescribed for a variety of infectious and inflammatory pathologies caused by microbes sensitive to ciprofloxacin. These include diseases of the throat (including tonsillitis), respiratory canals, pelvic organs, abdominal cavity, bones, skin, joints. Most often, this medication is prescribed for severe infections of the ENT organs.
Instructions for use
The medicine "Tsifran" with angina is taken orally, according to an individual scheme, depending on the severity of clinical symptoms and the course of the pathological process. Usually prescribed 250-750 mg 2 times a day. The duration of therapy is from 7 days to 4 weeks.
A single dosage of Cyfran from angina for intravenous administration is 200-400 mg 2 times a day, the duration of therapy is 1-2 weeks or more. You can enter the drug intravenously in a jet, but preferably drip.
When is the use of the drug necessary?
It is necessary to take the medicine "Tsifran" with such symptoms:
- Severe sore throat.
- General malaise.
- Fatigue, drowsiness.
- High body temperature.
- Fever.
- Inflammation of the lymph nodes.
- Ear and headaches.
Drug effectiveness
Against the background of taking “Tsifran”, tonsillitis, including in a purulent form, takes about 5-6 days, however, medical experts recommend that a full course of treatment be taken in order to completely destroy the pathogens. Many doctors prescribe this medicine in combination therapy, along with taking painkillers and antipyretic drugs, using a variety of antiseptic sprays for the throat. Also, while taking the “Tsifran” medication for sore throat in adults, it is recommended that regular gargling be performed to achieve a stable positive effect.
Side effect
The medical tool "Tsifran" in all dosage forms during the treatment of angina can cause the following negative reactions of the body:
- Digestive organs: dyspeptic disorders, diarrhea, pain in the abdomen, increased activity of liver transaminases, alkaline phosphatase, bilirubin, LDH, pseudomembranous colitis.
- CNS: feeling tired, cephalgia, dizziness, sleep disturbance, hallucinations, nightmares, visual disturbances, fainting.
- Urinary system: dysuria, crystalluria, polyuria, glomerulonephritis, albuminuria, a transient increase in blood creatinine, hematuria.
- The hematopoietic system: leukopenia, eosinophilia, a change in the number of platelets, neutropenia.
- Heart and blood vessels: heart rhythm disturbance, tachycardia, arterial hypotension.
- Allergic reactions: Quincke's edema, pruritus, Stevens-Johnson syndrome, urticaria, arthralgia.
- Local reactions: phlebitis, pain at the site of intravenous administration of the drug.
- Adverse reactions due to chemotherapeutic effects: candidiasis.
- Other reactions: vasculitis.
List of contraindications
Treatment of tonsillitis with the pharmacological preparation "Tsifran" is contraindicated in the following cases:
- the presence of sensitivity to quinols, including ciprofloxacin;
- lactation, pregnancy;
- age less than 12 years.
The use of this antibiotic by certain categories of patients is permissible only under the condition of medical supervision during therapy, these include:
- patients with a pronounced degree of cerebral arteriosclerosis;
- patients with circulatory disorders;
- people with diagnosed mental pathologies;
- patients with epilepsy and epileptic syndrome;
- patients with severe renal and hepatic insufficiency;
- elderly people.
"Tsifran OD" with angina
If the patient suffering from tonsillitis is prescribed a medication of antibacterial action "Tsifran" in tablet form, then the medication "Tsifran OD" would be the most successful choice. This is the same antibiotic, but differs from its predecessor in a more prolonged and enhanced action, as well as in higher dosages. Doses of the main active element in this drug are 500 and 1000 mg, which allows you to effectively eliminate sore throat through single doses of the drug per day.
In this case, one tablet of the drug "Tsifran OD" is prescribed per day. Convenience lies in the fact that many patients do not tolerate tablet forms of drugs, especially their frequent use during the day. Taking the pill once a day is much easier and easier for them. And if you consider that with angina, people have severe, almost unbearable sore throat, they experience significant difficulty in swallowing, so the best solution would be to take the medicine "Tsifran OD".
"Tsifran ST"
The drug "Tsifran ST" is somewhat different from the drug "Tsifran". This difference lies in the composition of the medication. In addition to the main substance ciprofloxacin, one more is included in it - tinidazole. This is a combined drug with antibacterial and bactericidal action of a wide spectrum. This makes it possible to treat with even greater success tonsillitis and other diseases of the ENT organs, since the range of pathogenic bacteria that are affected by this medicine is expanding significantly.
The dosage form of the drug "Cifran ST" is tablets that contain 250 mg of ciprofloxacin + 300 mg of tinidazole. Another dosage: 500 mg of ciprofloxacin + 600 mg of tinidazole.
The medical device “Tsifran ST” refers to combined preparations whose active elements are used in the treatment of infectious lesions due to the negative effects of anaerobic and aerobic microorganisms. Tinidazole has an antimicrobial and antiprotozoal effect. The mechanism of its action is based on the inhibition of synthesis and the violation of the structures of DNA-sensitive microorganisms, which in this case are: protozoa (Trichomonas vaginalis, Entamoeba histolytica, Lamblia spp.), Anaerobic microorganisms (Bacteroides fragilis, Eubacterium spp., Gardnerella vaginalis, Peptococcus, Peptococcus difficile, Fusobacterium spp., Peptostreptococcus anaerobius, Bacteroides melaninogenicus, Clostridium perfringens).
As you can see, unlike the drug "Tsifran", the antibiotic "Tsifran ST" with angina has a more powerful and wide antibacterial effect.
This medicine is prescribed mainly for infections of ENT organs: tonsillitis (including purulent forms), otitis media, sinusitis, pharyngitis, tonsillitis, mastoiditis, sinusitis, frontal sinusitis. In addition, this medicine successfully cures oral infections: periodontitis, periostitis, acute ulcerative gingivitis. What can replace "Tsifran" with purulent tonsillitis? Let's figure it out.
Klacid
The medicine "Klacid" is an antibiotic of the macrolide group, based on the active element clarithromycin. Its antibacterial effect is due to the suppression of the production of proteins of pathogenic bacteria and interaction with the 50S ribosomal subunit. The medicine "Klacid" effectively affects anaerobic and aerobic gram-positive and gram-negative microbes. It is also a very powerful antibiotic that is often prescribed for all forms of angina in adults and children. And what is better with angina: “Tsifran” or “Klacid”?
Drug Comparison
Both antibacterial drugs are quite effective for sore throats and are popular among doctors and patients. However, many people are interested in the question: what is better with this disease - "Klacid" or "Tsifran"? Unfortunately, there is no definite answer to it. Experts are of the opinion that each drug should be used strictly according to clinical indications, in accordance with laboratory studies, the main of which with angina, is bacterial culture for the sensitivity of microbes.
Thanks to the results of this analysis, the most suitable antibiotic is selected. Therefore, it is not advisable to use medicines without specifying microflora and without agreement with the doctor. In addition, the treatment should take into account contraindications that the patient has to take this or that medicine, which antibiotics have a lot of.
Reviews about this medication
Reviews of "Tsifran" with angina are positive and negative. Its powerful effect and high efficiency are described. Patients note that such drugs very well help with tonsillitis, including purulent, quickly normalize the condition, eliminate the cause of the disease. The throat ceases to hurt by about 3-4 days of illness, and the symptoms completely disappear by about 6 days. Despite the good effect, patients indicate in the reviews - “Tsifran ST” with angina has a bad effect on the digestive system, causes the development of diarrhea. In addition, nausea, pain in the stomach and intestines can occur from this medicine.
As for a medication such as "Klacid," in this case it should also be noted its pronounced positive effect, but at the same time, numerous adverse reactions. This drug was prescribed for many patients with angina, among them were adult patients and children.