Varicose disease in its various forms affects about 80% of women and 30% of men. This pathology is not fatal, but requires quality therapy. One of the popular drugs for its treatment is Reparil-gel. From our article you will learn what other diseases doctors prescribe this remedy for, how to use it correctly.
Description of the medication: composition and form of release
"Reparil-gel" is a drug that is produced in Germany. It has an anti-inflammatory and angioprotective effect. A pharmacological company produces a drug in three different forms:
- powder for injection (ampoules of 5 mg);
- dragee;
- spray;
- gel for external use (trade name "Reparil-gel N").
The main active component of the medication is escin. This is a vegetable glycoside, which is obtained from the fruits of horse chestnut. Aescin has a strong protective effect on blood vessels. In this case, the substance is characterized by a pronounced antiexudative effect, due to which the permeability of the walls of the capillaries decreases.
Pharmacokinetic properties
According to the instructions, the medicine is rapidly absorbed, and then evenly distributed on the surface of the vascular bed. The highest concentration of active substance in the body is observed 2 hours after application. The period of decay and elimination is up to 80 hours. The drug leaves the body with urine.
Indications for use
For which disorders and disorders is it advisable to use Reparil-Gel?
- Varicose disease (pathological changes in the venous wall).
- Thrombophlebitis caused by inflammatory processes on the inner lining of blood vessels.
- Phlebitis of superficial veins.
- Pain and heaviness in the legs, severe swelling.
- Impaired brain function due to injuries and concussions.
- Encephalitis.
- Hits, abrasions, sprains.
It should be noted that before using the drug, you need to consult a doctor. The doctor will prescribe a regimen, talk about possible side effects.
The mechanism of action of the drug
The main component of the drug - escin - has a venotonic effect, stimulating the activity of the adrenal cortex. As a result, the release of hormones of adrenaline and norepinephrine increases, playing the role of a kind of neurotransmitters. They sequentially bind to alpha-adrenergic receptors and contribute to narrowing of the lumen of blood vessels. Horse chestnut extract is also known for the ability to eliminate venous congestion observed with varicose veins.
"Reparil-gel" inhibits the synthesis of the enzyme hyaluronidase, which is responsible for the destruction of the molecules of hyaluronic acid. The latter controls the preservation of the natural elasticity of the walls of the veins, the content of the optimal level of fluid in the tissues of the vessels.
In general, the medication significantly improves blood flow in the limbs. It also reduces the risk of blood clots and is also characterized by the presence of antioxidant properties.
Instructions for use
The dosage and method of use of the drug is determined by the doctor, taking into account the patient's condition and the severity of his disease.
For adults with complicated thrombophlebitis and impaired brain function, the drug is prescribed only intravenously, 2 ampoules per day. For the treatment of encephalitis or hemorrhage, the dosage can be increased, but the daily amount of the medication should not exceed 20 mg.
Babies from one to 3 years are recommended to use the medicine in the form of a spray. It is administered intravenously at the rate of 0.1 mg per kilogram of body weight of the child. In the treatment of adolescent patients, the dosage should be increased to 0.2 mg per kilogram of body weight.
Varicose disease is also one of the indications for the use of Reparil-Gel. The use of the medication is permissible only on the recommendation of a doctor. If varicose veins are accompanied by phlebitis or impaired functioning of the valve apparatus, it is better to use a dragee or gel. Injections in this case are ineffective.
The course of treatment begins with taking one tablet after meals three times a day. As the patient's condition improves, the dosage can be reduced to two pills per day. Gel instruction recommends applying a thin layer on pre-cleansed skin areas. The procedure can be repeated several times a day. Strongly rub the product into the skin is highly undesirable.
Contraindications
The use of the medication is not recommended for people with impaired renal / liver function, as well as for women in the situation with Rh conflict.
About what “Reparil-gel” composition has is described a little higher. This information is always described in detail in the instructions, this is not at all accidental. The thing is that patients with intolerance to the active components of the drug should better abandon its use. Otherwise, the risk of developing allergies increases. If the patient has a similar reaction, it is necessary to note the treatment and consult a doctor. He will surely pick up an analogue tool with a similar mechanism of action.
Overdose, possible side effects
Numerous clinical trials prove that the use of the drug in the recommended doses does not cause side effects. Therefore, it is so important to clearly follow the instructions. When taking a dragee dose of more than 20 mg per day, symptoms of an overdose are not excluded. If fever or nausea develops, you should immediately stop treatment and consult a doctor.
As for the side effects, they are extremely rare. The most common among them are severe fever, skin rashes, and nausea. Cases of anaphylactic shock were not recorded.
Additional recommendations
Instructions for use informs that the medicine in any of its forms enhances the effect of anticoagulants. No negative interactions with alcohol were found. However, doctors do not recommend taking the drug with alcohol.
During pregnancy and lactation, medication is allowed, but only after consultation with your doctor. Ointment "Reparil-gel" is not recommended to be applied to the area of the mammary glands, especially when breastfeeding.
How much will the treatment cost?
The drug can be purchased at any pharmacy. A prescription from a doctor is usually not required. Its cost will depend not only on the regional margin of pharmacological networks, but also on the form of implementation. For example, powder for injection costs about 55 rubles per ampoule, gel for external use - from 150 rubles. The most expensive is the tablet form of the medication. For one package (100 pills) will have to pay a little more than 4 thousand rubles.
What patients say about the medicine "Reparil-gel"
Reviews about this medication are very diverse, but in most cases they differ in a positive color. Many patients use it to treat varicose veins courses. They note that a positive effect is manifested within a few days after the start of therapy.
Another important advantage is the composition of the drug. The presence of exclusively plant components minimizes the risk of side effects.
As noted above, the medicine goes on sale in several forms. Most patients give preference to gel and explain their choice of rapid absorption of the composition. After applying it, no film remains on the skin. Many simply forget to drink pills, and not everyone likes injections.