Consider the composition of the drug "Ursosan". The drug acts as a drug from a series of hepatoprotectors. They protect themselves from the harmful effects of liver cells, stabilize their membranes, and improve the functioning of the organ. The protective effect on the cells is associated with the numerous pharmacological properties of the drug, which relate to the improvement of bile outflow, prevention of the formation of stones and their dissolution.
It is used to treat any hepatitis (for example, infectious, alcoholic or toxic), biliary cirrhosis, cholestasis or fibrous degeneration of the liver tissue. Among other things, the medication is prescribed for patients with sclerosing cholangitis, reflux gastritis and esophagitis, as well as in case of a digestive disorder syndrome.
The composition of the drug "Ursosan" and the format of release
Currently, a drug called "Ursosan" is produced exclusively in the form of capsules, which are sometimes mistakenly called tablets. The capsule has a gelatin opaque shell, painted white. Inside each of them there is a powdery content with the same shade. The composition of Ursosan is described in detail in the instructions.
It is produced and sold in packs of 50, 10 or 100 capsules. The composition of the drug “Ursosan” includes ursodeoxycholic acid as an active component. Each pill contains 250 milligrams of this component. As auxiliary ingredients, Ursosan contains substances in the form of corn starch, magnesium stearate, colloidal silicon dioxide and gelatin.
Indications
Capsules are used for a wide range of various liver diseases, as well as for the prevention of toxic organ damage due to work in hazardous production or taking medications that have a negative effect. Many patients are interested in how good Ursosan is. The following pathological conditions are indications for the use of these capsules:
- Gallstone disease, without complications. In this case, the pills are taken in order to dissolve the stones in the gall bladder, as well as to prevent their appearance after cholecystectomy.
- In the presence of chronic active or acute hepatitis.
- The development of acute viral hepatitis or chronic opisthorchiasis.
- Against the background of toxic liver lesions (including medicinal or alcoholic ones).
- In case of alcoholic liver disease.
- With non-alcoholic steatohepatitis.
- With the development of primary biliary cirrhosis.
- The appearance of cholangitis, proceeding with sclerosis in the biliary tract.
- The development of cystic fibrosis of the liver.
- The presence of atresia (inferior development in the prenatal period of the bile ducts).
- Against the background of dyskinesia.
- The appearance of biliary reflux gastritis and reflux esophagitis.
- Digestive failure syndrome, which is associated with biliary dyskinesia.
- Prevention of harmful effects on the liver of antitumor drugs and hormonal contraceptives.
Consider the analogues of Ursosan and reviews.
Instructions for use
These capsules must be taken orally, they can not be chewed. About this warns the instruction. The composition of Ursosan is described above; the capsules are washed down with a sufficient amount of water. The best time to use the drug is in the evening. The dosage and duration of the course of therapy directly depends on the severity and type of pathology. On average, the dosage is calculated from a ratio of 10 milligrams per kilogram of body weight. For example, a person whose weight is 75 kilograms should take an average dosage of 750 milligrams, which corresponds to three pills.
For the treatment of gallstone disease (in order to dissolve the stones), the medication is taken in a dosage of two to five capsules daily for a long time. As a rule, the duration of a therapeutic course of treatment depends on the rate of dissolution of solid formations, and in addition, on the development of positive dynamics of the disease. Taking the drug can last several months or even years. He has a completely safe composition. The instructions for use of Ursosan are recommended to be drunk until the stones are completely dissolved, plus an additional three months in order to prevent the formation of new ones. All daily dosage should be taken once a day before bedtime.
To combat diffuse diseases of the liver, for example, chronic hepatitis or cirrhosis, the daily dose is calculated by weight, based on the ratio of 15 milligrams per kilogram of mass. For example, with 75 kilograms of weight, the amount of Ursosan is 1125 milligrams, which corresponds to five capsules. Next, the calculated daily dosage is divided into two or three doses per day. The resulting single dose of the drug is taken twice or three times with food. The course of therapy for such liver pathologies is usually long and may result in several years. The decision on the duration is made by the doctor, who starts from the dynamics of the pathology and the general condition of the patient.
To eliminate reflux gastritis, you need to take "Ursosan" one capsule in the evening before going to bed. The duration of treatment is determined by the dynamics of the disease and the rate of onset of positive changes. The course is ten days, but in some cases it can last two years. During this period, Ursosan can be taken without interruption.
In order to prevent the appearance of stones after cholecystectomy, you need to drink one capsule twice a day for four months. For the treatment of liver lesions of drug, toxic or alcohol origin, the daily individual dosage is calculated by body weight from a ratio of 15 milligrams per kilogram of weight. The resulting daily volume of the drug is divided into two doses. The single dosage calculated in this way is taken twice a day with meals for six to twelve months.
Therapy of biliary primary cirrhosis is carried out by Ursosan in a dosage calculated by weight from a ratio of 20 milligrams per kilogram of weight. Thus, in this case, the daily dose is 1,500 milligrams, which corresponds to six capsules. The resulting daily volume of the drug is divided into two or three doses. The medicine is taken for a period of six months to several years.
In the case of sclerosing cholangitis, the use of Ursosan at a dose of 15 milligrams per kilogram of mass per day is required. The daily volume is divided into three doses. The average single amount of medication is two capsules three times a day. Treatment of non-alcoholic steatohepatitis will require the use of a medication in a dose that is calculated by weight, based on a ratio of 15 milligrams per kilogram of weight. The resulting daily rate is divided into three doses per day. Therapy involves daily use of the drug for a long time period - from six months to several years. With cystic fibrosis, it is necessary to take the drug in an amount of 30 milligrams (nine capsules) per day, for a long time. This is indicated in the instructions to Ursosan. For children, the dosage is also indicated there. Let's talk about it below.
For newborns
Such babies may develop jaundice, which is a physiological condition if it lasts no more than three weeks. When, at the end of the indicated period, the disease does not recede, then we are talking about the presence of a pathological condition. If the disease gradually disappears, and by the first month after the birth of the child, it completely disappears, then this is considered a variant of the norm. As a rule, a gradual improvement in the color of the skin integument is allowed up to four months. In such situations, neonatologists are advised not to take any medication.
Jaundice among newborn babies is associated with the breakdown of a large volume of hemoglobin, which their liver is not able to quickly remove. But with a strong manifestation of pathology, when a high bilirubin content is fixed, damage to the nervous system is possible. In such cases, it is necessary to medically reduce the concentration of bilirubin.
In order to eliminate such severe jaundice, pediatricians recommend giving Ursosan to children. The drug is taken from two to four weeks in a row, daily for a quarter of the capsule. Doctors advise to pour the contents of the capsule onto a plate, divide it into four equal parts and, dissolving in water, give the child.
With good and positive dynamics (in the event that jaundice quickly disappears), you can reduce the therapeutic course to ten days. Weekly while taking this medication, you need to monitor the concentration of bilirubin in the blood. A weekly intake of "Ursosan" on average provides a decrease in bilirubin by 50 units. After reaching a bilirubin value of 100 milligrams per milliliter, the drug can be canceled. This is confirmed by the instructions for use with the drug "Ursosan".
How to take the remedy for children?
This medication can be used to treat various diseases of the liver and bile ducts in children. In this case, the dosage is calculated for each baby individually, which depends on his body weight. Typically, pediatricians come from a ratio of 10-20 milligrams per kilogram of weight. In this crumbs should be given in the evening the entire daily dose with food.
In the event that the child cannot swallow a large capsule whole, pour its contents into water, and then dissolve. Next, give the child drink “Ursosan” in the form of a solution. In this case, you must make sure that he drank it whole. It is worth noting that among children aged two to four years, difficulties with swallowing large capsules are quite likely, in this regard, it is necessary to check the time of taking the drug.
It is known that children of Ursosan are well tolerated. The instructions for use noted that the medicine helps in the treatment of acute hepatitis that occurs in childhood, as well as with various disorders of the bile outflow (for example, in the case of atresia of the bile ducts). In addition, the medication will certainly help to cope with various digestive disorders in children, which are formed due to the abuse of fried foods.
Can the body react negatively to the composition of Ursosan?
Side effects
Capsules, as a rule, are well tolerated by all patients, regardless of age, but there are still some side effects from them. Mostly this medication provokes undesirable reactions that affect the digestive system. We are talking, for example, about nausea, vomiting, diarrhea, constipation, a periodic increase in the activity of liver transaminases, calcification of stones and abdominal pain.
Such information is available in the instructions for use with the drug "Ursosan". It is worth noting that the development of diarrhea when taking the drug depends on the dose. That is, when using three capsules, the patient may develop such an unpleasant condition, and when using less medicine (one or two capsules), such a disorder will not occur. In this regard, in case of diarrhea against the background of “Ursosan”, the daily dosage should be slightly reduced.
In addition to negative effects on the digestive system, these capsules can provoke undesirable effects on the part of the functioning of other organs. For example, back pain is possible along with allergic reactions, itching of the skin and alopecia.
Contraindications
According to the instructions, the drug "Ursosan" has absolute and relative prohibitions on use. Relate to the age of children from two to four years. This is due to the fact that crumbs in this period of their lives may experience certain difficulties with swallowing large capsules. But, in principle, children can still take Ursosan, since this drug has no age restrictions. In the case of absolute contraindications, the medicine should not be used in any case. These prohibitions include the following conditions:
- The appearance of an x-ray positive structure of gallstones (when a high calcium content is noted in calculi).
- The presence of low functional activity of the gallbladder.
- The appearance of a gastrointestinal fistula and acute cholecystitis.
- Against the background of cholangitis and cirrhosis in the stage of decompensation.
- With liver and kidney failure.
- The appearance of blockage of the bile duct.
- The development of acute diseases of the gallbladder of an infectious nature, as well as the presence of empyema of this organ in a patient.
- The occurrence of sensitivity, allergies or intolerance to the components of Ursosan.
Analogs
A drug in the domestic pharmaceutical market has analogues and synonyms. We’ll figure out how to replace Ursosan. Many medicines have the same composition. That is, as the main active ingredient, they contain ursodeoxycholic acid. Of course, the doctor should choose the drug.
To date, the following analogues of Ursosan in the composition with ursodeoxycholic acid are available on the Russian market. These are drugs such as Livodex, Urdox, Ursodex, Ursoliva, Ursoroma Rompharm, Ursofalk, Ursodez, Ursoroma, Holudeksan and Exhol, as well as Allohol medicines and Cholenzym.
What else can replace Ursosan? The same composition is not always necessary for treatment.
Ursosan and the medicine Ursoliv
These medicines are synonymous drugs, that is, they contain the same substance in their role as an active component. True, Ursoliv is better tolerated by some people, while others, on the contrary, its rival Ursoliv. In such a situation, it is necessary to start taking the course of one medication, if for one reason or another it does not work, then it is worth switching to another. You can also read various subjective reviews about the effectiveness of these drugs.
For example, in some people the stones dissolved under the influence of Ursosan, while for others this medical tool did not help at all. But Ursoliv, on the contrary, helped achieve the expected effect. Thus, both of these drugs can have different effects in their effectiveness, which depends on the individual characteristics of the body.
In this situation, there are no objective signs by which it is possible to determine exactly who Ursosan is best suited to, and to whom its substitute Ursoliv. Therefore, you need to try both drugs, and then choose the most effective of them, based on your own subjective sensations.
The drug "Ursofalk"
According to the instructions for the Ursosan analogue, this pharmaceutical product is a medicine of the hepatoprotector category. It has choleretic, immunomodulating, cholelitholytic (dissolving stones) and hypocholesterolemic (lowering blood cholesterol) properties. The Ursofalk tool makes the membranes of the liver cells more resistant and durable, which prevents the destruction of the liver cells, stops the formation of fibrosis and normalizes the functioning of the liver. This is stated in the instructions for use.
The Ursosan analogue is used by doctors to dissolve stones in patients with gallstone disease. It is also necessary to achieve the normal functioning of this organ in the presence of biliary cirrhosis, sclerosing cholangitis, fibrosis, hepatitis, and toxic injuries (drugs, poisons, alcohol).
It is advisable to use it in case of dyskinesia, with reflux gastritis, and in addition, against the background of stagnation of bile. In addition, Ursofalk is used to prevent drug damage to the liver after courses of treatment with drugs that negatively affect this organ.
Make a choice
Ursofalk ”or“ Ursosan ”? We will try to compare the compositions of these funds below. Hepatologists, as well as infectious disease doctors, along with therapists, argue that Ursofalk is a more preferred drug than Ursosan. Doctors of these specialties base this recommendation on the result of clinical observation from their own practice, as well as starting from feedback from their own patients.
For example, according to patients, the synonym "Ursofalk" is tolerated by people much easier compared to "Ursosan". Doctors noted a higher rate of dissolution of stones and the normalization of the functional health of the liver under the influence of the composition of the Ursofalk tablets.
, . , «», , «». «», , , «».
Cost
- , . . :
- 160 190 .
- 750 840 .
- One hundred capsules costs from 1300 to one and a half thousand rubles.
Next, we will get acquainted with the opinion of consumers who took the pharmaceutical in question as part of the treatment of liver and gall bladder pathologies.
Reviews
The vast majority of comments on the Internet about the drug "Ursosan" is positive, since good effectiveness in relation to pathologies of the bile duct regularly helps people treat chronic ailments. For example, a number of patients who took this medicine in order to dissolve the stones note that the medication does an excellent job, and it is because of this that it is often possible to avoid surgical intervention aimed at removing the corresponding organ.
In addition, people point to the ability of Ursosan to effectively relieve colic, exactly like bouts of long-lasting gallstone disease. In addition, many patients take the medication in question due to nutritional errors, alcohol abuse, or after antibiotic therapy. It is noted that this drug helps to efficiently and quickly normalize the functioning of the gallbladder, while eliminating the severity of pain in the right hypochondrium.
People who suffer from chronic cholecystitis, and in addition, digestive system disorders while removing the gallbladder, write that Ursosan perfectly stops pain and discomfort in violation of the diet, abuse of fatty, fried foods and alcohol. People who suffer from hepatitis also note the positive effect of capsules, expressed in improving overall well-being. When it comes to the acute form of hepatitis, acceleration of recovery is noted along with the rapid departure of jaundice and the normalization of the color of the skin.
In the reviews, patients report a good composition of Ursosan tablets, it is often used as a prophylactic, well suited to support functional liver activity. This category of people, as a rule, takes Ursosan courses after various feast events, during which it is necessary to abuse harmful products.
Separately, it is worth talking about the reviews of parents whose newborn babies this medicine helps to eliminate neonatal jaundice. This category of consumers notes that due to the use of the described hepatoprotector, jaundice of babies passes very quickly, and the skin of a child acquires a normal color.
Despite the large number of good reviews, there are also negative comments about the composition of the Ursosan tablets. These are due to the fact that not everyone can dissolve gallstones and have to remove the organ operatively. In such cases, people expect that the Ursosan therapy is guaranteed to do without surgery, but even a long course does not always help to defeat the disease, formed by years of malnutrition.
As a result, patients feel disappointed, leaving negative feedback on the drug. Doctors, in turn, comment on this situation not with the uselessness of the pharmaceutical product, but with the degree of neglect of the disease, and therefore insist on regular examinations to prevent the formation of stones, starting from a young age.
We examined the composition of the drug "Ursosan" and instructions for it.