What could be more unpleasant than diseases of the genitourinary system? Such an attack is characterized by pain during urination, urinary incontinence, discomfort and pain in the pelvis and groin, pain in the lumbar region and other unpleasant sensations.
In case of detection of such signs of a possible disease, you should seek medical advice from a specialist, and not complicate the situation and do not self-medicate.
Often, doctors, examining the patient, find that the disease has no complications and it is likely to eliminate it without serious intervention. Then, experts prefer not to prescribe antibiotics, most of which have many side effects, but more “humane” but less powerful drugs.
One such remedy is Nitroxoline UBF.
Manufacturer
Nitroxoline tablets are familiar to many. They are often prescribed in cases of uncomplicated course of various diseases of the genitourinary system.
This begs the question: what is the difference between Nitroxoline and Nitroxoline UBF? In this case, the abbreviation UBF means the manufacturer - the Russian OJSC Uralbiopharm. Otherwise, both drugs are similar and have the same amount of active substance (nitroxoline).
According to the indications and contraindications, these drugs are absolutely identical, the difference may be in the color of the tablet shell (yellow, yellowish, orange), in the appearance of the package and in the number of tablets in it.
As for the manufacturer itself, Uralbiopharm has been engaged in the production and production of vital drugs included in the list of the Ministry of Health of the Russian Federation for almost a century. In addition, this company specializes in the production of drugs that are not inferior in quality to foreign counterparts, but much more affordable for Russian citizens.
Description
Round small biconvex tablets are coated with a shell of yellow, yellowish or orange.
Each tablet contains 50 mg of nitroxoline, the active substance.
The price of the drug "Nitroxoline UBF" will be from 50 to 100 rubles.
Pharmacology
The antibacterial drug has a fairly wide spectrum of action and has an antifungal effect.
Active against certain gram-positive bacteria. It is completely absorbed in the digestive tract.
Excretion of the drug is carried out by the kidneys.
Indications
When answering the question of why the Nitroxolin UBF tablets, pathologies such as:
- Infections of the organs of the urinary and reproductive systems: cystitis, urethritis, pyelonephritis, inflammation of the epididymis (epididymitis), inflammation of one or two testicles (orchitis), prostatitis, etc.
- Prevention of infections in the postoperative period, during surgical procedures (catheterization, operations on the kidneys and urogenital organs) performed on the urinary tract.
- Infected adenoma (benign tumor) or carcinoma (malignant tumor) of the prostate.
Dosage and route of administration
Inside while eating.
Adult patients: 100 mg 4 times a day.
The maximum dose for adults per day is 800 mg.
The maximum allowed dose per day is 1-1.2 grams.
Children under 5 years: 50 mg per day.
Children 5 years and older: 50-100 mg 4 times a day.
Depending on the weight, children are prescribed Nitroxoline UBF from 10 to 30 mg per kilogram of weight per day in 3-4 doses.
Frequency of admission per day - every 6-8 hours.
The minimum course of treatment is 10-14 days.
The standard course of treatment is at least 2-3 weeks.
Repeatedly, the drug can be prescribed no earlier than a 2-week break.
For the prevention of infections in the postoperative period, Nitroxoline UBF is prescribed 2 tablets (100 mg) 3-4 times a day, lasting from 2 to 3 weeks.
Since the drug is available in packs of 10, 20, 30 and 50 pieces, based on a long course of treatment, it follows that a large package is more profitable to purchase than a small one.
Side effect
Not always safe "Nitroxolin UBF". Instructions for use warns of the following side effects that may cause the drug:
- Digestive disorder in the form of loss of appetite, nausea or vomiting.
- In extremely rare cases, the drug can lead to impaired liver function.
- Allergies: Itchy skin and rash.
- In rare cases, from the nervous system: polyneuropathy, headache, paresthesia, ataxia.
- With prolonged use, a single case of the development of inflammation of the optic nerve is described.
- From the side of the heart and blood vessels: in very rare cases, tachycardia.
Contraindications
- Intolerance to nitroxoline, increased susceptibility to derivatives of 8-hydroxyquinoline.
- Neuritis, polyneuritis.
- Glucose-6-phosphate dehydronase deficiency.
- Liver failure.
- Difficulty urine discharge or a small amount.
- Cataract.
- Pregnancy and lactation.
Application features
It is necessary to take into account some features of the patient’s body, which are warned by the instructions for use attached to the Nitroxolin UBF preparation in order to prevent complications of the patient’s condition.
With caution, the drug is taken with renal failure (possibly excessive accumulation of the active substance in the body in case of poor excretory capacity of the kidneys).
During treatment, the patient's urine acquires a reddish-yellow color.
Released by prescription.
Reviews
Patients made their opinion on the drug Nitroxoline UBF. Reviews about it come down to the fact that the drug is inexpensive and there are no problems with the presence of it in pharmacies. As for the effectiveness of the therapeutic effect in various inflammatory processes, opinions were divided.
Nitroxoline tablets help most people. They cope even with chronic cystitis, when from the slightest cold there are cramps in the urethra. According to patients, Nitroxolin helped them get rid of these symptoms on the second day of treatment.
Many people like that the drug is not an antibiotic, and therefore does not have those side effects and serious effects on the body, as powerful drugs. But at the same time, one should not expect a miracle from these pills. They act more sparingly on the body, but the course of treatment is quite long, and you need to take a lot of tablets to stop the disease.
The medicine "Nitroxoline UBF" helps children with cystitis. The symptom of this disease is pain during urination. The reason most often is the colds of the pelvic organs due to sitting on cold surfaces. Therefore, doctors when confirming cystitis in a child of school and preschool age often prescribe Nitroxoline.
The drug may be ineffective in some cases. In addition, without a full course of treatment and prevention, Nitroxoline may not work at all. This is especially noted by people with chronic diseases who are used to being treated with potent drugs.
As for the side effects of taking the drug, then most people do not experience them. Sometimes these pills can cause nausea, and they invariably stain urine in a reddish yellow color. But basically, without serious symptoms.
At the same time, the advantages of Nitroxoline include the absence of dysbiosis and thrush, which are constant companions in antibiotic treatment.
Many are interested in the question about the Nitroxolin UBF preparation: after what time does it begin to help? Everything here is individual and depends both on the severity of the disease, and on the body's immunity and other individual characteristics.
There were cases when the drug helped eliminate soreness or fever in one day. Those who suffer from a chronic form of diseases of the urinary and reproductive systems prefer to take mini-courses of treatment for prevention, taking 3-4 tablets per day for 5 days. This helps relieve symptoms and drown out the disease. But this must be discussed with your doctor.