Gastroprotectors are drugs that are astringents, mucous membranes, enveloping agents that relieve pain spasms, envelop the mucous membrane, thereby protecting it from the aggressive effects of gastric juice.
Gastroprotective functions
Gastroprotectors are special medicines designed to protect the delicate mucous membrane of the stomach from exposure:
- Pepsin.
- Hydrochloric acid and other aggressive compounds that can destroy the gastric mucosa.
Gastroprotectors are medicines that are used for diseases of the gastrointestinal tract, such as:
- Erosion of the esophagus and stomach.
- Stomach ulcer.
- Duodenal ulcer.
Gastroprotectors are means that:
- Increase mucosal resistance to environmental influences.
- Mechanically protect the mucosa.
- At the same time protect the esophagus, stomach and intestines and increase the resistance of the mucosa to environmental influences.
The peculiarity of gastroprotectors is that they are created on the basis of natural preparations, without chemistry, which provides effective protection without harming other organs and without causing allergic reactions.
The list of gastroprotective drugs is quite large. The most popular of them are listed below.
Ventrisol
It is used for people suffering from gastritis, gastric ulcer, inflammation of the mucous membrane of the duodenum. Accelerates the healing process of the affected areas of the digestive tract. Envelops only ulcerated areas of the stomach or duodenum. The price of "Ventrisol" is acceptable, it is an inexpensive drug.
Together with proteins formed from tissues lacking epithelium, the drug forms a substance that is not amenable to dissolution. It fills the affected areas of the stomach and protects it from the destructive effects of acid. It makes it possible to recover damaged tissues. Available in tablet form. The price of Ventrisol is approximately 150 rubles.
Do not use it for pregnant women and mothers who are breast-feeding a baby.
Neointestopan
The drug has an adsorbing and enveloping effect. It brings the intestinal flora to a normal state. Covers the stomach and duodenum with a thin film. It reduces intestinal cramps and has a positive effect on the irritated mucous membrane of the stomach.
It makes the contents of the intestines thick and improves the consistency of the stool. It is used for food allergies and acute diarrhea caused by food poisoning, as well as for violation of intestinal microflora.
It is contraindicated in children under 3 years of age, and pregnant women should be used with caution. Among the side effects, constipation is observed.
You can take the drug for no more than two days. Available in tablet form.
Analogs of Neointestopan: Neostopan, Capect, Reaban.
De Nol
This drug protects the mucous membrane and tissues of the stomach, and also neutralizes the aggressive environment. Refers to bacterial agents. The drug is able to destroy microbial cells. The drug affects the stomach and duodenum. Prevents the development of peptic ulcer. In the stomach it becomes a colloidal solution. Thanks to this, the mucosa is protected from the action of gastric juice.
The drug restores damaged tissues of the stomach. Comprehensively affects problems in the intestines and stomach. It has astringent, antiseptic, antibacterial and healing effects. The drug is in the form of tablets.
Indications for use of the drug "De-Nol" are as follows:
- gastric and duodenal ulcer;
- chronic gastritis;
- dyspepsia and diarrhea;
- irritable bowel syndrome.
Ulgastran
It belongs to the same pharmacological group. It is used for gastric and duodenal ulcers, inflammation of the mucosa and various types of gastritis. Protects the gastric mucosa from acids. Forms a protective film on damaged areas of the stomach and duodenum. Allows to bile bile acid and pepsin.
It acts as a painkiller and allows you to accelerate the restoration of damaged sections of the stomach and duodenum. The composition includes aluminum salt. Reduces pepsin activity and increases prostaglandin production. When dissolved in an acidic medium, forms an adhesive mass with unusual properties. Creates a barrier protecting damaged areas of the stomach.
Available in tablet form.
"Sukrat"
The mechanism of action of the gastroprotector: has a protective effect on the mucous membrane of the stomach and intestines. Available in the form of tablets, in a package - 10 pieces.
This gastroprotective drug, interacting with proteins of necrotic ulcer tissues, creates protective layers that help prevent the subsequent destructive effect of pepsin, hydrochloric acid and bile salt. Helps to increase the synthesis of prostaglandin, reduces the active effects of pepsin and binds a bile salt. It inhibits the active activity of pepsin by 30%. It gives a weak antacid effect.
"Kaopektat"
The gastroprotective drug belongs to the antidiarrheal pharmacological group. The action of the drug is the adsorption of toxins, bacteria and gases while normalizing the composition of the intestinal flora. Thanks to the astringent effect, it relieves irritation of the intestinal mucosa, relieves cramping.
The medical preparation "Kaopektat" is actively used for the following gastrointestinal dysfunctions:
- acute diarrhea of various origins (infectious, allergic, medicinal);
- toxicoinfection;
- diseases associated with disorders in the intestinal microflora.
The drug "Kaopektat" is not prescribed for children under 3 years old, children from 3 to 6 - with caution. Contraindications for prescribing the drug may be hypersensitivity, fever.
As a side effect, constipation is noted, various allergic reactions can occur.
Venter
Venter is a medicine from the pharmacological group of gastroprotectors. This drug has an antiulcer effect. The effect is achieved due to the formation of a protective layer on the mucosa, which counteracts the destructive effect of hydrochloric stomach acid or bile salts on the stomach.
The medicine "Venter" is actively prescribed for stomach ulcers or duodenal ulcers. The drug has a low absorption, 90% of it in the primary composition is excreted through the intestines, a small percentage can be excreted through the kidneys.
The drug "Venter" pregnant and during breastfeeding should be used with caution and under the supervision of a doctor.
Contraindications for the purpose of the drug are: hypersensitivity, kidney disease, obstruction and bleeding in the digestive tract.
Possible side effects: constipation, nausea, dry mouth, slight drowsiness, mild itching.
Ankrusal
Ankrusal is a medical product from the pharmacological group of gastroprotectors, the main therapeutic substance of which is sucralfate.
The pharmacological action of the drug is the formation of a protective layer on the walls inside the stomach and the absorption of bile salts. "Ankrusal" is used during the course prescribed by the doctor for diseases of the digestive tract and metabolic pathologies:
- stomach ulcers or duodenal ulcers;
- peptic ulcers of unknown location;
- clinical conditions resulting from a violation of acidity;
- gastroesophageal reflux;
- certain diseases of the urinary system (hyperphosphatemia with uremia).
The drug Ankrusal is contraindicated in case of hypersensitivity, gastrointestinal obstruction, gastrointestinal bleeding, as well as pregnant women.
It should be noted that the drug is poorly absorbed, does not accumulate in the tissues and part of the drug taken (95-97%) is excreted in feces. As a side effect, constipation is noted.
Alsucral
Also included in the list of gastroprotective drugs. It refers to the type of film-forming agents, it is used for people suffering from a stomach ulcer.
Forms a protective layer in the form of a film, reduces the effects of pepsin and increases the production of Pg. When dissolved in an acidic environment, the drug turns into a sticky mass endowed with alkaline qualities. The stomach is converted to a polyanion with negative charges.
Protects damaged areas of the mucosa. It also protects the mucosa from aggressive substances. Weakly interacts with the mucosa, thus enhancing the protection of the mucous membrane and allows you to protect from the action of substances such as bile.