Almost everyone after forty-five years suffers from high blood pressure. Unfortunately, hypertension cannot be completely cured, so patients have to regularly take pills for pressure until the end of their lives to neutralize the attacks of hypertension, which can suffer a lot of negative consequences. For example, from severe headache to serious illness.
Monotherapy gives a positive effect only at the initial stage of the disease. The maximum effect is achieved with complex therapy with the use of two or three drugs from different therapeutic groups, which must be used constantly.
It is important to consider that the body gets used to any antihypertensive drugs over time, and their effect becomes weaker. Therefore, for a stable normalization of blood pressure, their frequent change is necessary, which only a doctor can carry out.
The patient should know that drugs that lower blood pressure are immediate and prolonged action. Medicines from different pharmacological groups have different mechanisms of influence, that is, to achieve a stable antihypertensive effect, they affect different processes in the body.
Therefore, a medical specialist may prescribe different drugs to different people with high blood pressure, for example, one drug is better for one to stabilize the pressure, and the other is better for the other.
In addition to a direct decrease in pressure, it is necessary to influence the cause of its increase: for example, eliminate atherosclerosis, as well as prevent secondary diseases - myocardial infarction, cerebral microcirculation disorders. What is the best cure for pressure that older people should take?
Pharmacological groups of antihypertensive drugs
To lower the pressure, drugs from different therapeutic groups are used. Sartans include:
- "Losartan."
- "Valsartan".
- Candesartan
Selective and non-selective blockers:
- "Atenolol".
- "Metoprolol".
- Propranolol
- "Bisaprolol".
Blockers:
- "Terazosin".
- "Urorek".
ACE inhibitors are considered good medications for pressure:
- Captopril.
- Enalapril.
- Prestarium.
Diuretic drugs:
- "Indapamide".
- Furosemide.
- "Hydrochlorothiazide".
- Veroshpiron.
Calcium blockers:
- Verapamil.
- Diltiazem.
These drugs are recommended by doctors to eliminate arterial hypertension of any severity. A medical specialist, choosing a drug for a patient, is guided by the following indicators:
- stage of the disease;
- age;
- the presence of concomitant diseases;
- individual characteristics of the body;
- frequency of administration and compatibility of drugs.
According to doctors, the best modern drugs for pressure are drugs from the group of angiotensin II receptor blockers. They are the most promising and effective in the elimination of hypertension.
Their pharmacological effect is due to the blocking of nerve endings to angiotensin II, a powerful vasoconstrictor microelement that provokes a persistent and sharp increase in blood pressure in the body. The drug with prolonged use has a powerful pharmacological effect without the appearance of any negative results, as well as withdrawal syndrome.
It must be understood that only a cardiologist or therapist can prescribe medications for high pressure, as well as monitor the patient's condition during treatment. Do not engage in self-medication, as this can lead to negative consequences. What blood pressure medications are best for older patients?
The list of effective drugs
The most effective medicines for lowering blood pressure are the following:
- "Losartan."
- "Valsartan".
- "Indapamide".
- "Hydrochlorothiazide".
- Enalapril.
- Captopril.
- Nifedipine
- Lisinopril.
- Verapamil.
- Amlodipine.
- "Metoprolol".
- Diltiazem.
- "Lozap".
- Lorista.
- Nortian.
- "Teveten."
- Arifon Retard.
- "Lorvas SR".
What medications for pressure are better for older people? The following drugs are often prescribed:
- Hypothiazide.
- Enap.
- Burlipril.
- "Kapoten".
- Cordaflex.
- Diroton.
- "Lysinotope".
- Finoptin.
- Isoptin.
- Flamon.
- Norvask.
- Amlodac.
- Amlokor.
- Metocardium.
- Egilok.
- Cardil.
- "Diacordin".
Diroton
The medication refers to angiotensin - converting enzyme inhibitors . When using the drug, the active ingredient is instantly absorbed into the blood. Under the influence of Diroton, a person's blood pressure level decreases, his ability to withstand loads increases, and his arteries expand, which leads to better microcirculation of vital organs.
With the constant use of the drug in a patient, hypertrophy of the heart muscles decreases, blood supply to the myocardial sites with ischemia improves. Diroton is a good medicine for lowering blood pressure.
The medication prolongs the life of patients who suffer from chronic heart diseases. The tablet begins to act within an hour after oral use and retains its pharmacological effect for about a day.
The therapeutic effect in the elimination of arterial hypertension in humans is observed approximately a couple of days after the start of the course and reaches maximum levels develops within one month of admission. With a sharp cessation of taking the drug in a person, withdrawal syndrome appears, which leads to an increase in blood pressure.
Diroton is recommended to be taken by patients once a day, in the morning, without chewing and drinking with water. The drug is best taken before breakfast.
The daily dosage and duration of treatment with a medication is determined by a medical specialist, depending on the diagnosis, the course of the disease, and the general condition of the patient.
When eliminating hypertension, it is necessary to remember that the pharmacological effect does not appear immediately and reaches a maximum one month after the start of treatment. If, after fourteen days from the start of drug therapy, the patient does not feel any improvement or his condition, on the contrary, worsens, it is imperative to contact a medical specialist again and undergo an examination.
At the initial stage, treatment with a medicine to reduce blood pressure indicators to a person under the supervision of a doctor can use other antihypertensive drugs, given that the pharmacological effect of Diroton appears gradually.
Diltiazem
The main component of the drug (hydrochloride) reduces the intake of calcium ions due to the calcium channel blocker. This blockage of calcium channels, as a rule, applies to heart cells, as well as blood vessels. Due to this effect, it has a number of therapeutic effects:
- Reduces heart pain by improving blood microcirculation in the coronary arteries and lowering myocardial oxygen and micronutrient requirements.
- Reduces blood pressure by reducing the tone of the smooth muscles of arterial capillaries and expanding their lumen.
Diltiazem is considered a good cure for high blood pressure for the elderly.
Before starting therapy with Diltiazem, you need to carefully read the annotation. Since the drug has a number of certain specific instructions that you need to pay attention to, they include:
- A sudden cessation of therapy can lead to an anginal attack in the form of pressing pain in the heart.
- You can not combine "Diltiazem" with beta-blockers, as this can lead to a decrease in pharmacological action and the appearance of adverse reactions.
- "Diltiazem" comes into contact with a huge number of medicines, so when using them it is important to warn the doctor about this.
- With extreme caution, use the medication for diseases of the liver and kidneys, in children and people of retirement age.
- You can not perform work that requires increased attention due to the possible occurrence of adverse reactions from the nervous system.
In pharmacies, Diltiazem tablets are dispensed strictly according to the prescription of a medical specialist.
"Isoptin SR"
The drug is produced in two dosage forms:
When administered intravenously, Isoptin can provoke a transient decrease in blood pressure, which, as a rule, is not clinically manifested, but may be accompanied by dizziness. The insufficiency of microcirculation before treatment should be compensated by diuretic and cardiac glycosides. Isoptin is also the best cure for high blood pressure.
According to the instructions for use with Isoptin, in people with severe or moderate heart failure, acute progression of circulatory failure may occur during therapy.
The drug in tablet form is taken orally, swallowed whole and washed down with water. It is best to use the Isoptin medication during or immediately after eating. Method of admission:
- The use of the drug is determined individually, taking into account the severity of the disease and the clinical picture. For all recommended indications, the average daily dosage is 240-480 milligrams.
- With long-term treatment, exceeding the daily concentration of 480 mg is not recommended. In the maximum daily dosage, the drug should be used only in a medical facility.
- The initial single concentration of the active substance is 40-80 milligrams, the frequency of use is three to four times a day. For patients with functional disorders of the liver, treatment should be started with a single dose of 40 mg. Frequency of admission - three times a day.
- In the future, the concentration of the active component by a medical specialist selects individually. Isoptin in the form of a solution for injections can be administered only intravenously.
- Infusion of the drug should be carried out slowly with continuous monitoring of the electrocardiogram and blood pressure for two to three minutes. The initial dosage is from 5 to 10 milligrams.
Enalapril
The drug is available in tablet form, intended for oral use. The main component of the tablets blocks the connection of the angiotensin-converting enzyme, which is responsible for the level of total blood pressure. Enalapril is considered one of the best medicines for lowering blood pressure in hypertension.
Due to which several physiological actions of the medication are carried out, which include:
- Reduced heart load.
- An increase in the minute volume of blood that the heart pushes out in one minute.
- Increased resistance of myocardial cells to low blood flow, as well as oxygen and micronutrients.
From the instructions for use "Enalapril" it is known that after taking the drug, the active substance is completely absorbed into the systemic circulation. It evenly spreads in the tissues, does not transform and is excreted unchanged from the body with urine.
Use of the drug is indicated to prevent high blood pressure in hypertension. Enalapril is also used for combination therapy of chronic heart diseases.
Hypertension drugs with a quick effect
The list of the best medicines to normalize blood pressure:
- Anaprilin.
- Furosemide.
- Captopril.
- Adelphan.
With high blood pressure, it is enough to put a Captopril or Adelfan tablet under the tongue, keep until completely dissolved. The pressure will begin to decrease after thirty minutes. But you need to know that the effect of the use of such medicines is short-lived. For example, "Captopril" a patient should take three times a day, which is not always possible to do.
Furosemide is a good medicine for lowering blood pressure. The effect of the drug, which refers to loop diuretics, is the rapid onset of severe diuresis. Within an hour after drinking from twenty to forty grams of the drug and in the next six hours, the patient will often begin to visit the toilet in order to empty the bladder. Blood pressure will decrease by eliminating excess fluid, as well as relaxing the smooth muscles of the vessels and reducing the volume of circulating blood.
Sustained release tablets
The list of antihypertensive drugs that have a long-lasting effect:
- Propranolol
- "Metoprolol".
- "Losartan."
- "Bisoprolol".
They have a prolonged pharmacological effect, such drugs are designed for more convenient treatment. It is enough to use these medications once or twice a day, which is quite convenient, since hypertension is indicated by the doctor on an ongoing basis until the end of his life.
These drugs are used for long-term complex therapy for hypertension of the second or third degree. Features of the application are a long cumulative effect. To obtain a lasting result, you must use these medicines for three weeks or more, so it is not recommended to stop using the drug if the pressure has not decreased immediately.
List of the best medicines for high blood pressure
The list of drugs that lower blood pressure is compiled according to the reviews of doctors who prescribe the following drugs in their practice. Starting from the most effective with few negative effects to agents with more frequent adverse reactions. List of the best drugs:
- "Losartan."
- Lisinopril.
- "Renipril GT".
- Captopril.
- Indopamide.
- Veroshpiron.
Losartan
The medication belongs to the group of sartans. The spectrum of exposure is to stop the powerful vasoconstrictor effect of angiotensin two on the human body. This drug has increased activity. The drug blocks the nerve endings, thereby preventing the narrowing of the capillaries. "Losartan" is on the list of the best medicines for pressure (elevated).
The upper and lower blood pressure levels decrease after the first oral administration of "Losartan", the largest - after six hours. The positive effect lasts about one day, after which it is required to take the next dose.
Persistent normalization of pressure should be expected about a month and a half after the first dose. The medicine is suitable for combating hypertension in people with diabetes.
Advantages of the drug "Losartan":
- Powerful and persistent antihypertensive effect.
- Excellent tolerance, minimal adverse reactions.
- It is convenient to take (once a day).
"Losartan", according to reviews, is a good cure for pressure, without side effects. There are no negative reactions when taking, in rare cases, migraine, dizziness, nasal congestion may appear.
Generics of "Losartan":
- "Lozap".
- Xartan
- "Cardomin-Sanovel".
- "Vazotens".
- "Renicard".
“Valsartan”, “Eprosartan”, “Telmisartan” - medicines from the same group, but “Losartan” and its substitutes are more effective. Clinical studies have proven its high effectiveness in eliminating high blood pressure even in people with complicated hypertension.
Lisinopril
Belongs to the group of angiotensin-converting enzyme inhibitors. The antihypertensive effect is observed already an hour after the use of the desired concentration of the drug, increases in the next six hours to maximum levels and the day remains.
This is a medication with a prolonged cumulative effect. According to the instructions for use, it is known that daily dosing is from 5 to 40 milligrams, use once a day in the morning.
When eliminating hypertension, patients note a positive effect from the first days of treatment. "Lisinopril" is considered one of the best medicines for high blood pressure.
Benefits:
- Stably maintains blood pressure.
- Enhances the tolerance of the muscles of the heart to stress in diseases of the CVD.
- It prevents the progression of heart muscle hypertrophy and an increase in the volume of the left ventricular chambers in patients with severe hypertension or who have suffered a heart attack.
- It is well suited to eliminate high blood pressure in patients with heart failure, as well as diabetes and heart attack without a history of hypotension.
Minuses:
- Dry cough.
- Dry mouth.
- Hyperhidrosis (a pathology that is accompanied by severe sweating).
- Lowering blood pressure below normal.
- Dizziness.
Substitute List:
- Renipril.
- Lysacard.
- Lysinoton.
- Lysigamma.
"Renipril GT"
This is a complex medication that consists of enalapril maleate and hydrochlorothiazide. Together, these components have a more intense antihypertensive effect than each separately. Pressure decreases gently and without loss of potassium.
Positive sides:
- High efficiency.
- Good tolerance.
- The maximum content of the active component in the blood is reached after two hours and is maintained throughout the day.
Cons drug has contraindications:
- Allergy to active ingredients.
- Pregnancy.
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Positive points:
- Ease of use (once a day in the morning before meals).
- Safe for patients with thyroid disease, because it does not affect the level of lipids and glucose in the blood.
- It shortens the left ventricle.
- Price.
It is forbidden with a low content of potassium in the blood, as well as with severe renal failure or serious violations of the liver, allergic reactions to the active substance of the drug. Not recommended for people with lactose intolerance.
Analogs:
- "Acripamide".
- "Perinides".
- Indap.
Veroshpiron
Potassium-sparing diuretic drug. Use one to four times a day in courses. It has a strong diuretic effect, but does not remove potassium from the body, which is necessary for the normal functioning of the heart.
Use only in the complex treatment of high pressure. Subject to the prescribed dosages, it does not provoke negative reactions, with rare exceptions. Long-term therapy in high concentrations of the active substance (more than 100 milligrams per day) can lead to hormonal disorders in women and men.
Complex drugs for high blood pressure
The best cure for pressure is combination drugs, which consist of several components at once. It:
- "Noliprel" - the composition of the drug includes Indapamide and Perindopril.
- "Aritel plus" - the medication contains "Bisoprolol" and "Hydrochlorothiazide".
- "Exforge" - the composition of the drug includes Valsartan and Amlodipine.
- "Renipril GT" - has in its structure "Enalapril" and "Hydrochlorothiazide".
- "Lorista N" - the composition of the drug includes "Lozartan" and "Hydrochlorothiazide".
The combined use of several drugs for high blood pressure
Combination therapy is the most effective in eliminating hypertension. To achieve a lasting positive effect helps to simultaneously use two or three medications necessarily from different therapeutic groups.
How to combine tablets from high pressure? Examples:
- Diuretic and beta-blocker - Chlortalidone and Bisoprolol.
- Diuretic and sartan - "Losartan", "Valsartan" and "Hydrochlorothiazide".
- The beta-blocker and calcium channel blocker from the dihydropyridine group are Metoprolol and Felodipine.
- An ACE inhibitor and calcium antagonist are Benazepril, Enalapril, and Diltiazem.
Conclusion
There are a huge number of drugs for high blood pressure. With hypertension of the second and third degree, patients are forced to use medications regularly to keep the pressure normal. Combined treatment is best suited for this, due to which a good antihypertensive effect is achieved without hypertensive crises. Only a doctor should prescribe a medicine for pressure. Before making a choice, he will take into account all the features and only then he will select a specific drug.
For each person, a specific treatment regimen is drawn up, which he must adhere to and constantly monitor blood pressure. If the prescribed therapy is not effective enough, you should again contact a medical specialist to adjust the dose or replace the medicine with another drug. Do not engage in self-medication, as this can lead to sad consequences.