The medicine "Xarelto" is a direct-acting anticoagulant. The product is produced in the form of coated tablets, which contain the active component - micronized rivaroxaban.
Pharmacological properties
The instruction “Xarelto” explains that the mechanism of action of the drug lies in the direct slowdown of factor Xa. The active substance has high bioavailability and selectivity for internal use. The medicine is rapidly absorbed, and the highest concentration is observed 2-3 hours after taking the pill. Most of the active substance binds to plasma proteins.
Indications for use
The Xarelto manual indicates that tablets containing 10 mg of rivaroxaban are prescribed to prevent venous thromboembolism in patients who have undergone surgery on the lower extremities. A dosage of 15 mg and 20 mg is used to prevent stroke and systemic thromboembolism in people who have atrial fibrillation of non-valve origin. In addition, these capsules are used to treat deep thrombosis, pulmonary artery thromboembolism, and to prevent recurrence of DVT and pulmonary embolism.
Contraindications
The instruction "Xarelto" prohibits the use of the drug for hypersensitivity, gastric, intracranial and intestinal bleeding. The drug is not prescribed for already taken anticoagulants of another variety, in conditions with a high risk of bleeding, during pregnancy. The medication should not be taken with severe renal failure, liver pathologies with manifestations of coagulopathy, patients under the age of 18, with hereditary intolerance to lactose and galactose.
Side effects
The instruction "Xarelto" informs that the use of tablets can cause negative effects for the body. Taking the medicine is associated with the risk of occult or overt bleeding from any tissue or organs that can lead to post-hemorrhagic anemia. In addition, the tool can cause dizziness, weakness, headache, shortness of breath, shock, an increase in the size of the limbs and other hemorrhagic complications.
The drug "Xarelto": instruction
20 mg and 15 mg (dosage of the drug) can be taken only with meals, 10 mg tablets are used regardless of food intake. After complex surgery on the knee joint, the duration of therapy is about two weeks, with severe interventions in the hip joints, treatment lasts five weeks. The initial volume of the drug is taken 6-7 hours after the operation if hemostasis is achieved. The total therapeutic dose is 1 capsule per day. If you miss a pill, you need to take it immediately. The drug should be used regularly. To compensate for the missed dose, doubling the number of tablets is prohibited.
Means "Xarelto": instructions, price
The cost of the drug is 1500-2600 rubles. The instruction indicates the presence of analogues, which include the drug "Rivaroxaban".