According to the instructions for use, Aspirin tablets for adults and children are prescribed if there is a need for a non-hormonal drug to stop the activity of inflammatory foci. The drug is prescribed primarily to relieve pain, as well as relieve fever. You can use "Aspirin" as an effective medication that prevents thrombosis.
When will it help?
The instruction for use of Aspirin tablets states: the drug is indicated for the relief of pain symptoms. It is reasonable to use the medication for soreness of a weak and medium level of strength. The tool is effective for a syndrome of various etiologies, including inflammatory processes. The clinical practice of the use of tablets and powder "Aspirin" to alleviate fever, the patient's condition associated with rheumatic processes is widespread. You can use the medication as a preventive with an increased likelihood of embolism, the formation of blood clots.
In the instructions for use of "Aspirin" children and adults are shown to use the composition inside. It is allowed to grind each instance of the medication before use for food, but this is not necessary: you can swallow the tablets whole. In any of the Aspirin options, drink plenty of clean water without additives.
Application Nuances
In general, 100 mg of Aspirin is recommended for use in the amount of 3-10 tablets at a time. You can repeat the reception after 4-8 hours. You can not use more than four grams of the drug in 24 hours. As a means to prevent embolism, blood clots, the drug is prescribed once per day in the amount of 1-3 tablets. The duration of the course varies from a month to a couple of years.
Instructions for use "Aspirin" 100 mg for children recommends taking in less than adult patients. The specific dose is calculated based on the weight of the patient. For every kg of mass should be no more than 60 mg. The total dose is divided into 4-6 servings. You can use Aspirin with four-hour intervals in the amount of 10 mg / kg, or with six-hour intervals, increasing the dose by one and a half times.
Special case: for children - with caution
The instructions for the use of Aspirin tablets at a temperature and to change the viscosity of the blood, to relieve pain, are allowed to be used from six months old. When prescribing the drug to children under one year of age, a single dose varies between 50-100 mg. Before reaching the age of three, it is allowed to use one tablet at a time, until the age of six - two. For children of the age group of 7-9 years, 300 mg of the drug is allowed at a time. Over nine years of age - 400 mg.
If the pathological condition is accompanied by fever, the instructions for use "Aspirin" is allowed only if other means have shown inefficiency. A study of numerous cases of drug use by children and adolescents showed that the risk of the formation of Reye's syndrome increases. This condition manifests itself in profuse vomiting, which does not stop for a long time.
Indications: "Aspirin Cardio"
Instructions for use with this form of release indicate the effectiveness of the drug as an element of a comprehensive course of recovery of the patient's condition after a heart attack. The drug is used to stabilize the brain when blood flow is disturbed in this organ.
Aspirin Cardio prevents vascular blockage and is effective in inflammatory, infectious processes.
Do I need this?
As can be seen from the reviews, the instructions for using Aspirin are simple and understandable, the price of the drug is accessible to the masses, and the medicine itself is effective and quick to act. Many of our compatriots always keep Aspirin tablets on hand, so that in case of pain or heat, they can quickly alleviate the condition. As a drug for the main treatment, the drug is not used, it is shown only as a means of alleviating the symptoms. This is also noted in the responses about the effectiveness of the tool. It is worth noting that the best opinion about the medicine has developed among those who used the pills under the supervision of a doctor. "Aspirin" is sold without a prescription and is available for purchase to all interested, nevertheless, you should coordinate the appointment with the doctor - it is safer and more effective.
Alternative: is there?
Reviews, analogues, instructions for use of "Aspirin", indications for its use, possible side effects - all this information is of interest to many of our compatriots. Although Aspirin is available to the general public, many are interested in having an alternative. Someone needs a stronger tool, others need more security or a slightly wider spectrum of action. Currently, pharmacists can offer the following analogues of Aspirin, the instructions for use of which contain mention in the composition of acetylsalicylic acid:
- "Acetylsalicylic acid".
- "Thrombo ACC."
- "Uppsarin Upps."
Pharmacological features
In the instructions for use of Aspirin Cardio, the manufacturer indicates that the product belongs to the class of non-steroidal anti-inflammatory drugs and suppresses the activity of inflammatory foci. This is an analgesic that does not have a narcotic effect. The tool reduces blood coagulation. The main compound due to which the effect is achievable is acetylsalicylic acid. A drug substance irreversibly inhibits the activity of COX, an enzyme produced in the human body that is involved in the production of prostaglandins. In addition, COX is involved in the formation of prostacyclins, thromboxane.
The reduction in prostaglandin generation mentioned in the Aspirin instructions for use leads to a weakening of the pyrogenic effect exerted by these compounds on the centers regulating body temperature. The activity of prostaglandins decreases, affecting the sensitivity of nerve endings. The effect of pain mediators on the nervous system is reduced.
How it works: continuing to review
Instructions for use "Aspirin Cardio" draws attention to the irreversible process of preventing the formation of thromboxane. This explains the antiplatelet result of taking the drug.
At the same time, the active combination of tablets inhibits the COX of the endothelium, where prostacyclin is produced. This compound also has an antiplatelet effect. Studies have shown that the COX of the endothelium is less affected by acetylsalicylic acid, when compared with the effectiveness of the platelet enzyme. In addition, inhibition of activity relative to COX of the endothelium is assessed as reversible. This explains the effectiveness of the drug as a blood thinner. In the instructions for use of "Aspirin", the manufacturer indicates the need to use the product for this purpose carefully so as not to provoke excessive inhibition of the ability of the liquid to coagulate.
Composition specifics
In the instructions for use of "Aspirin Cardio", the manufacturer mentions the presence of several tablet options: there is a drug made in capsules coated with a thin film, there are effervescent tablets. The first option is acetylsalicylic acid, protected by compounds resistant to the influence of gastric juice. Using this option helps to minimize the likelihood of a negative effect on the part of the gastric system.
Effervescent tablets, as stated in the instructions for use (Aspirin Cardio is not available in this form), contain sodium bicarbonate. This substance is able to enter the neutralization reaction of hydrochloric acid, which explains the increased acidity of the gastric environment. Under the influence of the substance, the indicators stabilize to 6-7 units, therefore, the irritating effect of the main element of the drug on the mucous membranes of the stomach, intestines is reduced.
It's important to know
The instructions for use of Aspirin Cardio, Aspirin pay particular attention to the use of the drug in the presence of liver diseases. Although this is not an absolute contraindication to taking the composition, the presence of such a diagnosis in the history of the disease makes it necessary to carefully approach the development of a therapeutic program. Similar limitations are associated with a history of gout.
You can not simultaneously take "Aspirin" and other drugs to relieve pain and stop the activity of inflammatory foci. This significantly increases the likelihood of side effects, can cause the failure of each of the funds separately.
Mutual influence
As explained in the instructions for use of "Aspirin", acetylsalicylic acid can stimulate the result of the effect on the human body of methotrexate. This is due to a decrease in clearance of the drug substance in the kidneys. In addition, the compound is displaced from bonds with whey proteins.
The combination of acetylsalicylic acid and heparin enhances the effectiveness of the second substance. A similar effect is observed when combined with agents that indirectly reduce the ability of blood to coagulate. The effect is due to the effect on platelet function. Indirect anticoagulants are displaced by acetylsalicylic acid from bonds with serum protein structures.
A combined therapeutic course, which involves the intake of acetylsalicylic acid and thrombolytics, antiplatelet drugs, ticlopidine, leads to increased activity of these groups of medicines. Instructions for use "Aspirin" clarifies that the drug lowers the clearance in the kidneys of digoxin, while stimulating the increased content of this substance in the circulatory system. This leads to greater composition efficiency.
Combining, do no harm: joint effects
In the instructions for use of "Aspirin" (tablets for blood thinning, pain relief and heat removal), the manufacturer specifies: acetylsalicylic acid makes hypoglycemic drugs more active and effective. This is especially pronounced with respect to insulin, sulfonylurea transformation products. The effect is explained by the hypoglycemic qualities of the acid itself, on which Aspirin is based, as well as its ability to displace sulfonylurea products from serum bonds.
The combination of uricosuric medicines and Aspirin is accompanied by a decrease in the effectiveness of the first group of drugs. Especially carefully it is necessary to prescribe acetylsalicylic acid if benzbromarone is prescribed to the patient.
The combination with glucocorticosteroids is characterized by increased activity of the elimination of salicylates.
Too much!
Excessive use of Aspirin can cause an overdose of moderate or severe levels. The first expresses itself by nausea and vomiting. The patient is noisy in his ears, his ability to hear is weak, his head is sore and dizzy, his consciousness is confused. Severe poisoning indicates a fever and alkalosis, acidosis, increased pulmonary ventilation. Possible coma, failure of the lungs, heart and blood vessels. Severe Aspirin poisoning can cause severe hyperglycemia. An overdose of overdose is more likely in elderly patients.
Having revealed the fact of excessive use of "Aspirin", it is necessary to immediately provide first aid. With an average level of severity, the patient's condition is reduced in the dosage of the medication used, in the severe case they are hospitalized. Emergency treatment involves the use of activated carbon, gastric lavage. It is necessary to take indicators to clarify the acidity of the environment in the digestive tract, to conduct diuresis, blood dialysis. A serious condition with an overdose of “Aspirin” requires infusions and a course of medications, selected based on the symptoms of the case.
Carrying out alkaline diuresis, the goal is set to an acidity level of 7.5-8 units. Forced diuresis is indicated if the salicylate content in the blood serum fraction exceeds 500 mg / g (for children, the upper limit is 300 mg / m).
Application Nuances
If Aspirin is prescribed for acute heart attack, the optimal dosage is 100 mg of the drug for 24 hours. As a measure to prevent a recurrence of the situation, the dose is tripled.
To prevent a stroke or blood flow problems in the brain, 100-300 mg of the drug should be used daily.
It is impossible!
"Aspirin" is contraindicated in persons suffering from erosion, ulcers in the stomach or intestines. You can not use the drug for asthma, which is activated against a background of non-hormonal anti-inflammatory, salicylates. An absolute contraindication is the need to consume 15 mg of methotrexate or a larger dose per week. “Aspirin” is not prescribed if hemorrhagic diathesis, insufficiency of the kidneys, liver, and also a decompensated form of insufficiency of cardiac functionality are revealed.
"Aspirin" is contraindicated in case of high blood pressure and angina pectoris. The medication is not used if the thyroid gland is larger than normal sizes. The drug is not suitable for the treatment of pregnant women in the first and third parts of the term, as well as at the stage of breastfeeding.
"Aspirin" is contraindicated in case of hypersensitivity to acetylsalicylic acid. It cannot be used if other salicylates provoked a hypersensitivity reaction in the past. This applies to auxiliary components of the drug. To minimize the likelihood of a negative response from the body, you should carefully read the instructions for a specific release for the presence of compounds hazardous to a particular person.
Safety Above All
For patients under the age of fifteen, “Aspirin” is contraindicated in case of fever, SARS. Infection with viruses in combination with drug therapy can provoke Reye's syndrome. The term refers to a serious condition in which there is an insufficiency of the liver in acute form, fatty liver dystrophy and encephalopathy.
Special occasion
It is allowed to use Aspirin, but only if possible regularly check the condition of the body if a person suffers from hyperuricemia or gout. Particularly careful treatment is required by people whose medical history mentions peptic ulcers in the stomach, intestines, bleeding in this area, as well as malfunctioning of the liver or kidneys. With caution, a remedy is prescribed when mentioning in the past episodes of bronchial asthma, allergies, localized in the respiratory system, transferred hay fever.
Use of "Aspirin" in the second third of the period of pregnancy is allowed. The drug can be used only under the supervision of a doctor. Caution requires the use of a composition against the background of polyps in the nose and with a tendency to an allergic response to various medicinal compounds.
Is it dangerous?
It is forbidden to combine “Aspirin” and alcohol. Such a combination is more likely to provoke undesirable body responses, increases the toxic effect of medications, alcohol. For the entire period of the therapeutic course, any alcohol-containing products and drinks should be completely abandoned.
Negative consequences: what is possible?
The manufacturer clarifies in the instructions for use that in some cases, “Aspirin” provokes a deterioration in appetite and pain in the abdomen in patients. Pills can cause loose stools and nausea. Some have ulcers, erosion, and bleeding in the digestive tract against the background of the therapeutic course. There is a risk of an allergic response to the body. Laboratory tests may show a decrease in platelet concentration.
Possible vomiting while taking the drug, as well as hidden bleeding. With a probability of less than one percent, liver damage due to poisoning may develop. To a greater extent, such risks are peculiar to persons suffering from juvenile rheumatoid arthritis. With a similar frequency (less than one percent), anemia is recorded against the background of the use of “Aspirin”. There is a risk of glomerulonephritis in acute form.
An allergic response to taking the medication can be expressed by skin manifestations, rashes, itching, hives, Quincke's edema, allergic rhinitis, bronchospasm and shortness of breath are possible.