The drug "Neopenotran" (suppositories), instructions for use reports, is a combined medication used in gynecology, the action of which is aimed at eliminating fungus and pathogenic microorganisms. The composition of the drug has an antibiotic in combination with an antifungal component.
One vaginal suppository contains one hundred milligrams of miconazole nitrate and five hundred milligrams of metronidazole.
One of the active ingredients - metronidazole - is a derivative of 5-nitroimidazole, it has an antimicrobial effect and is active against protozoa. Miconazole also provides a fungicidal effect. The specified substance disrupts the synthesis of the components of the cell membrane of the fungus, which leads to the death of the latter.
The pharmaceutical preparation "Neopenotran" (suppositories), the instruction informs, is characterized by good absorption both in people with vaginitis and in healthy individuals. It is noted that after using the medication in question, its active active component is not detected in blood plasma. Metronidazole in small amounts is adsorbed into the systemic circulation. The process of its metabolism occurs in the liver. The elimination half-life makes from six to eleven hours.
The medication "Neopenotran" (suppositories) instructions for use prescribes use for local therapy of vaginitis (both Trichomonas and bacterial). In addition, it is prescribed for fungal vaginal infections, as well as those infections, the source of which was a mixed flora, sensitive to the components of the drug in question.
The drug "Neopenotran" (candles). Instruction manual
It should be borne in mind that the duration of the therapeutic course and the optimal dosage are determined by the specialist individually.
Candles "Neopenotran" appoint administered, as a rule, once a day before going to bed. Place the suppository in the vagina as deep as possible. On average, a course of treatment lasts fourteen days.
If there is a need to achieve a quick therapeutic effect, two candles are installed daily (one each in the morning and evening hours). In this case, seven days of treatment is enough.
A special cap is enclosed in each cardboard pack with the drug, it provides a convenient introduction of the suppository.
There is no need for dose adjustment for elderly patients.
When using the drug "Neopenotran" (suppositories), patient reviews confirm this, local undesirable consequences may occur. Systemic effects, as a rule, do not develop (due to the low absorption of the drug with its intravaginal use).
Local negative effects: burning, itching, hyperemia of the perineum. With infection of the vagina, accompanied by an inflammatory process, discomfort may increase on the first or third day of treatment with the specified medication. In a situation where side effects are pronounced enough, drug therapy is stopped.
Systemic undesirable effects (extremely rare): dizziness, headaches, irritability, impaired coordination of movements, perversion of taste, convulsions.
If side effects occur, consult a doctor.
The drug in question is not prescribed for patients with hypersensitivity, in early pregnancy, during lactation, with epilepsy, a tendency to seizures, with severe liver diseases, as well as in childhood.
It is noted that this medication is highly recommended not to combine with alcohol. Failure to do so will endanger the patient’s health.