The drug "Metronidazole" is a powerful tool against the simplest organisms of the spore-and non-spore-forming group. They started using it for a long time, so there are a lot of drugs containing the same active substance. However, the tool should be used very carefully, especially in a number of circumstances and individual patient indications. For example, uncontrolled use of the Metronidazole preparation during pregnancy is dangerous. In such situations, the likelihood of developing pathology and even fetal death is very high. In this publication, we will consider the main properties of this medication, as well as the reasons for the establishment of restrictions on its appointment to women during the period of gestation.
What is the drug Metronidazole?
During pregnancy, women are contraindicated in almost all potent drugs. During this period, her body becomes vulnerable, and a close relationship with the fetus does not allow to distinguish between therapeutic effects. The manufacturer indicates that the drug is one of the derivatives of 5-nitroimidazole. Doctors attribute it to antiprotozoal and antimicrobial agents. The effect of metronidazole on the fetus is due to its high ability to penetrate into all fluids of the human body. However, recent studies have proven that treatment with the drug in question is still possible.
Indications for taking the medication "Metronidazole"
During pregnancy, the use of the drug is possible only in exceptional cases. For example, one of the possible indications is AAD (antibiotic-associated diarrhea). According to American researchers, in this case, the use of metronidazole is a much safer method than treatment with vancomycin. According to them, no pathologies were found in the children of the tested women who were treated during pregnancy. However, in Russia these recommendations have not yet been verified, and the effect of metronidazole on the fetus is still considered negative and dangerous.
General indications for taking the drug are trichomoniasis, vaginitis, urethritis, bacterial infections caused by giardia, trichomonads and other anaerobic-type microbes. Indications include ulcerative gingivitis. In addition, it is used as one of the means in radiation therapy.
Contraindications for taking the drug "Metronidazole"
During pregnancy and lactation, as a rule, the drug is not prescribed, since these conditions are restrictions for use. It is also not recommended to conduct therapy using the drug in question for patients with:
- leukopenia;
- organic brain damage;
- hypersensitivity;
- liver failure;
- impaired coordination.
Individual intolerance, as well as a number of contraindications, can only be determined by a doctor, so only after a detailed examination and consultation with a specialist can you decide on treatment with Metronidazole. The description of the drug allows the professional physician to take into account all possible risks and avoid negative consequences.
Side effects
Conventionally, all possible side effects are divided into systemic and local. Systemic include metallic taste, dizziness, vomiting, spastic and headaches, nausea, leukocytosis, leukopenia, urine staining in a bright brown or red color. Local side effects include genital burning, increased urination, vulvitis and vaginal candidiasis. In addition, the patient may experience various allergic reactions. Most often it is a urticaria.
In pregnant women, as a side effect, fetal development defects may occur. Especially dangerous, according to manufacturers and researchers, the drug "Metronidazole" in the first trimester.