The medicine "Ornidazole", analogues of the drug (for example, "Lornizol", "Tiberal", "Avrazor" and others) are antimicrobial and antiprotozoal agents. Medications are used to eliminate and prevent anaerobic infections, giardiasis, trichomoniasis, amoebiasis.
The medicine "Ornidazole" (reviews and comments of experts confirm this) does not inhibit aldehyde dehydrogenase. In this regard (unlike the medicine "Metronidazole") it is compatible with alcohol.
Means "Ornidazole" after penetration into the gastrointestinal tract undergoes a fairly rapid absorption. The drug reaches its maximum concentration within three hours. The drug "Ornidazole" penetrates into the cerebrospinal fluid, other tissues and body fluids.
The drug is metabolized in the liver. The elimination half-life is about thirteen hours. After a single use, about 85% of the drug is excreted during the first five days, mainly in the form of decay products. Approximately 4% is excreted in the urine in unchanged form.
The drug "Ornidazole" (reviews of experts confirm this) is effective for genitourinary infections provoked by Trichomonas vaginalis (vaginal trichomonas) in men and women.
The medication is used for amoebiasis (all intestinal infections associated with the activity of Entamoeba histolytica dysenteric amoeba, all extraintestinal forms, amoebic abscess in the liver).
The medicine "Ornidazole" is also recommended for giardiasis.
The medication is prescribed for the prevention of infections provoked by anaerobes during operations on the colon, as well as in gynecology.
The drug "Ornidazole" (reviews of experts confirm this) should be taken only after a meal.
With trichomoniasis, 500 mg is prescribed twice a day (in the mornings and evenings). The treatment lasts five days.
To exclude secondary infection, the sexual partner also needs to undergo a therapeutic course.
For children with this disease, 25 mg per kilogram of weight is prescribed per day. The resulting amount of the drug is taken once.
With giardiasis, the drug is prescribed at a dose of 1.5 grams (with a patient weighing more than 35 kilograms) once. The medication is taken in the evening.
For children whose weight is less than 35 kg, 40 mg per kg per day is prescribed.
The duration of therapy is one to two days.
In the treatment of anaerobic infections, the drug is taken every twelve hours at a dose of 500 mg.
With amoebiasis, the dosage regimen and dosage are set individually.
The medication "Ornidazole" (reviews of doctors are unambiguous in this) is not prescribed for hypersensitivity.
In various studies involving animals, no toxic or teratogenic effects of the drug on the fetus were detected. However, adequately controlled studies in humans have not been conducted. In this regard, the appointment of the drug to pregnant or lactating women is carried out only by absolute indications.
When taking the medicine "Ornidazole", the occurrence of drowsiness (mild), gastrointestinal tract disorders, headaches is likely. In a number of cases, tremor, dizziness, short-term loss of consciousness, and coordination disorder were noted. The reactions of individual intolerance, signs of mixed neuropathy should also be attributed to undesirable manifestations.
In case of an overdose, an increase in side effects is noted. In addition, depression develops, epileptiform convulsions occur.
When prescribing, caution should be exercised with patients with CNS pathologies (multiple sclerosis, epilepsy, damage to the brain).
When taking high dosages, there is some risk of developing hepatic dysfunction in patients with liver damage who abuse alcohol, as well as in children, lactating and pregnant women.
The drug "Ornidazole-Vero" (patient reviews indicate this) does not differ in its effectiveness from the above medication.
Before using the medicine, consult your doctor.