The active ingredient of the Eglonil preparation is sulpiride, a benzamide antipsychotic with moderate antipsychotic activity. This pharmaceutical agent has a stimulating, antidepressant effect on the body.
"Eglonil" (instructions indicate) in the central nervous system blocks dopaminergic receptors that are in the limbic system. To achieve the antipsychotic effect, the optimal dose of sulpiride is more than 600 mg. A dose of up to 600 mg is prescribed in order to obtain a stimulating, antidepressant effect.
In reduced doses, sulpiride is additionally administered in the treatment of diseases of a psychosomatic nature. "Eglonil", the instruction indicates, effectively stops the negative manifestations of gastric ulcer. In patients with irritable bowel syndrome who take sulpiride, a decrease in the intensity of abdominal pain is observed.
At low doses, sulpiride (50-300 mg) eliminates dizziness.
Eglonil: instructions for use
The drug is combined with other pharmaceutical psychotropic drugs or used as monotherapy:
- with acute and chronic form of schizophrenia;
- in acute delirious conditions;
- with depression of various origins;
- with neurosis, a sense of anxiety, manifested in adult patients;
- with severe behavioral disorders in children over six years of age, including those with autism (50 mg).
Eglonil: dosage instructions
Solution
In order to stop acute psychosis (as well as in a chronic form), sulpiride injections are prescribed intramuscularly at a dosage of 400 mg to 800 mg. Treatment is designed for up to 14 days.
Egonil tablets
In cases of acute and chronic schizophrenia, an attack of delirious psychosis, depression, the doctor chooses a daily dose from 200 mg to 1000 mg, divided into 2-3 doses.
Egonil Capsules
In the treatment of neurosis and anxiety in adults, a daily dose of 50 mg to 150 mg is prescribed for up to 4 weeks.
In severe behavioral disorders in children, with autism, the daily dose is calculated in an amount from 5 mg per 1 kg of a child’s body weight to 10 mg per 1 kg.
For patients who have reached advanced age, the dose of sulpiride at the beginning of treatment is ¼, or ½ of the usual recommended dose.
With concomitant diagnoses, in particular renal failure, the doctor reduces the dose of the drug, increases the interval between administration.
Eglonil: side effects
Violations in the endocrine system are possible: the development of reversible hyperprolactinemia, which is manifested by galactorrhea, amenorrhea, menstrual irregularities, very rarely observed symptoms of gynecomastia, impotence and frigidity. Sometimes patients complain of excessive sweating, the appearance of excess weight.
The activity of liver enzymes increases.
The central nervous system responds to prolonged use of Eglonil: drowsiness, dizziness, tremor, early dyskinesia.
In medical practice, there have been rare cases of tardive dyskinesia, which is expressed in involuntary movements of the tongue, face after prolonged use of Eglonil.
When hyperthermia occurs, sulpiride is canceled because elevated body temperature indicates the likelihood of developing a diagnosis of “malignant antipsychotic syndrome” (ZNS).
The cardiovascular system sometimes responds to Egonil intake with tachycardia, high blood pressure, very rarely - the development of orthostatic hypotension, lengthening the QT interval.
Allergic reactions are manifested by skin rash.
Eglonil: instruction (contraindications)
Sulpiride is contraindicated in patients with prolactin-dependent tumors, hyperprolactinemia, intoxication, in a state of affect, manic psychosis, with pheochromocytoma. You can not take "Eglonil" nursing mothers.
Intravenous injections of sulpiride are prohibited for children under 18 years of age, as well as capsules for children under 6 years of age.
It is not recommended to combine dopaminergic receptor agonists and sultoprid with sulpiride.
The drug is contraindicated in case of hypersensitivity to one of the ingredients.