Among modern antifungal drugs , the solution “Loceryl” can be especially noted. Instructions for him recommend using this medicine as an external remedy. It relates to potent drugs used for the prevention and treatment of fungal diseases of the nails. There are two very convenient dosage forms for this drug. The most convenient to use is the Lotseril nail polish. It is produced in bottles of 2.5 and 5 ml. The drug contains the active substance - 5% amolorphine solution. Another no less convenient form of release is a 5% solution in 2.5 and 5ml bottles. To date, there is no other data on other forms of release of the drug "Lotseril". Tablets, creams and ointments under this name are not sold in pharmacies. In 1 ml of solution contains 50 mg of active substance. Excipients in the preparation are triacetin, copolymers of methacrylic acid, ethyl acetate, ethanol, butyl acetate. In packages with this medicine, 16 tampons for cleaning nails, 10 special spatulas, 30 disposable files are included.
Indications for use are fungal infections of the nails caused by different types of mushrooms. In monotherapy, the drug is used when no more than 2/3 of the nails are affected. Prevention of fungal infections can be carried out continuously.
The drug "Lotseril", the instructions for use of which guarantee a relatively quick disposal of the fungus and its prevention, have a rather high cost, although health costs such money. This drug has a fungicidal, fungistatic effect on pathogens. The active substance - amolorphine - changes the state of the cell membrane of a fungus by a method of disruption in its biosynthesis of sterols. The active substance of the drug is able to inhibit two different enzymes involved in the synthesis of ergosterol - delta7-8-isomerase and delta-14-reductase. Amolorphine is active against the vast majority of fungi that cause nail diseases.
The drug "Lotseril", instructions for use
Varnish and solutions are applied to the affected nail plates of the fingers of the extremities 1-2 p. in Week. Active substances penetrate the nail plate in 24 hours. Treatment continues until complete regeneration of the nails and cure of the fungal disease. Usually, therapy lasts up to 6 months. In severe cases, it is extended to 12 months. Application of the drug "Lotseril" instruction recommends starting with the preparation of nails. To do this, the affected areas of the nail plate are removed as much as possible with the help of a nail file attached to the medication. The next processing step is cleaning the surface of the nail and degreasing it with a swab dipped in alcohol. This procedure should be carried out before each application of the drug. The drug "Lotseril" (solution and varnish) is applied to the entire surface of the nail with the help of a special spatula that comes with the medicine. The drug dries in a few minutes. All affected nail plates are treated. Nail files used in the treatment of diseased nails are not used to care for healthy ones.
Side effect
During the use of the drug in places of its application, burning, itching, hyperemia are possible.
Contraindications:
- sensitivity to chemicals that make up the drug;
- lactation period;
- pregnancy;
- childhood.
To protect the treated nails while working with any organic solvents, you need to wear rubber gloves. During treatment with Lotseril, the instructions to it categorically prohibit the use of false nails and cosmetic varnish.
The shelf life of the drug is 3 years. It is stored in closed containers at a temperature not exceeding 30 ° C.