There are a number of very unpleasant, but, unfortunately, common diseases that need to be treated immediately. Antiprotozoal and antimicrobial agents are used to combat a number of microbes, one of which is Metronidazole, known among the inhabitants. Instructions for use with the drug contain information on the classification of the active substance of the drug as derivatives of five-nitroimidazole. Externally, the active substance of the drug looks like a greenish crystalline powder. The drug "Metronidazole" is produced in the following forms:
- tablets with a shell and without it;
- suspensions;
- powders for the preparation of solutions and ready-made solutions for infusion and intravenous administration ;
- vaginal suppositories;
- vaginal tablets;
- creams;
- external and vaginal gels.
Pharmacological properties
The properties of Metronidazole are based on the ability to invade the body of a microorganism and stimulate the synthesis of its constituent DNA (nucleic acids). The result of this effect is the death of bacteria, and, consequently, recovery.
Indications for use
For protozoal infections, infections of the central nervous system, bones, joints, infections of the skin and soft tissues, as well as ulcers of the digestive tract of bacterial origin, doctors prescribe Metronidazole. The instruction provides the following indications:
- trichomoniasis;
- giardiasis;
- Trichomonas urethritis;
- abscesses of the internal female genital organs, liver;
- endometritis;
- peritonitis;
- gastritis;
- sepsis.
In addition, among the indications there are postoperative conditions, as well as other diseases, inflammations associated with the vital activity of microorganisms.
The medicine "Metronidazole" - contraindications
Contraindications for the use of Metronidazole are few. These include:
- epilepsy;
- damage to the organic type of the nervous system;
- renal failure;
- lactation;
- allergic reactions to the active or excipients of the drug;
- pregnancy;
- leukopenia.
Metronidazole is especially dangerous for pregnant women and the fetus in the first trimester. During this period, taking the medicine can provoke a miscarriage, a fetal freeze and other negative consequences.
Dosage and administration
Determines the method of use of such a drug as Metronidazole, instructions. For each form of release, the dosage regimen and dosage are determined separately.
Tablets
Tablets are prescribed in courses of 1 tablet up to three times in one day. More often they are taken at the rate of 0.25 mg twice or thrice per day. The course of treatment can be determined from three to ten days. The final dosage regimen, as well as the method of administration, is determined by the attending physician.
For vaginal infections, doctors prescribe gel, suppositories, vaginal tablets and Metronidazole Cream to the patient. The instruction prescribes the use of funds subject to full sexual rest at 2 g once a day, or 500 mg twice a day. As a rule, the course of treatment is ten days, but in some cases it can be reduced.
Externally, gels and creams are used for several weeks and even months, the use is continued even in the case of a therapeutic effect in order to avoid relapse.
The order of injection is determined by the doctor based on the severity of the disease and the condition of the patient.
Side effects
Among the side effects may occur:
- digestive system disorders;
- disorders of the central nervous system;
- problems with the urinary system;
- allergies
- other types of manifestations of a negative nature.
"Metronidazole" is an effective medicine, but the doctor should establish the possibility of its use. Uncontrolled administration of the drug can lead to severe disorders and require long-term treatment.