In the article, we will consider instructions and reviews for Binafin.
Damage to the nail plate by the fungus, called onychomycosis, is a common problem in modern medicine. Every fifth person on our planet is faced with the problem of fungus on the nails. It is quite simple to become infected with onychomycosis; one contact with the pathogen is enough. This occurs as a result of non-observance of personal hygiene rules, as well as when using the personal effects of an infected person. To cure onychomycosis completely is a complex and lengthy process.
Many are mistaken that the fungus on the nails can be cured simply using local means with an antiseptic effect. Such patients have to spend years of unsuccessful attempts to cure the pathology. The lack of positive dynamics indicates improperly selected treatment. Therapy of the fungus often requires an integrated approach, involving both the use of external agents and oral medications.
One of the commonly prescribed drugs for the treatment of onychomycosis is Binafine. It is produced in various forms, including cream (sometimes called ointment), as well as tablets. This allows you to solve the problem of fungus on the nails comprehensively. Reviews about "Binafine" are abundant.
Structure
The active ingredient is terbinafine. This substance has a wide spectrum of action and is active against candida and mold strains, as well as dermatophytes.
In a tablet form of the drug, in addition to the active component, there are such auxiliary substances as povidone, magnesium stearate, starch, talc, sodium methyl paraben, sodium glycolate starch, etc. The content of terbinafine in one pill of the drug is 125 or 250 mg. Reviews on Binafine tablets are mostly positive.
In addition, the medication is in the form of a cream, the content of the active substance in which is 10 mg. In this case, the main substance is terbinafine hydrochloride. The following substances act as auxiliary components in the cream:
- Purified water.
- Liquid and white paraffin.
- Sodium phosphate is acidic.
- Ketosteryl alcohol.
- Propylparaben.
The properties
Many experts explain the effectiveness of Binafin in the fight against nail fungus by the property of the active substance to inhibit the production of protein by fungal cells. A similar effect on pathogenic cells provokes a lack of ergosterol and an excess of squalene content, which over time causes the death of the fungal pathogen. Terbinafine, being the active substance of the drug, stops the production of an enzyme called squalene oxidase, which allows for a destructive effect on the cellular structures of pathogens.
According to reviews, “Binafin” relieves the fungus very quickly.
The agent quickly penetrates the affected area. The concentration of terbinafine in the horny nail structure increases 10 times after two days of using the drug. After two weeks of treatment, the concentration of the drug increases by another seven times. Stability in the funded process is observed in the results of clinical studies on the tenth day of drug use. The process of elimination of the drug is prolonged and ranges from several weeks to five months. Such a long period of elimination of the active component allows patients to receive action from the drug over a large amount of time.
"Binafin" minimally affects the systemic work of the body. If we are talking about a cream, then only 5% of terbinafine enter the systemic circulation. The processed residues of the drug are transformed into metabolites and exit with urine through the urinary tract.
Indications
"Binafin" in tablet form is prescribed to treat damage to the fungus not only of the nails, but also of the scalp. If the pathological process has spread over large areas and is due to candidiasis, an oral form of the drug is also prescribed.
Indications for the use of the drug in the form of a cream are the following pathological conditions:
- Multi-colored variety of lichen.
- Dermatomycosis of various origins.
- Damage to the nail plate and skin cover with strains of candida fungus.
According to reviews, the cream "Binafin" is suitable for almost everyone and rarely causes adverse reactions.
Contraindications
The drug is contraindicated for use by children under two years of age, and in the case of cream, the age limit is imposed up to 12 years. In addition, you can not prescribe the drug with a revealed hypersensitivity to the components that make up the antifungal agent, as well as against the background of pathological disorders in the liver.
Adverse reactions
According to reviews of Binafine, the most common adverse reactions to the use of the drug are the following symptoms:
- Nausea.
- Arthralgia.
- Myalgia.
- Violation of taste perception.
- Bowel disorders.
- Abdominal pains.
- Fullness of stomach.
Reviews of Binafin ointment confirm that when using it, allergic reactions from the skin, such as burning, rash, redness and itching, are not ruled out. If the patient notices the symptoms of urticaria, then the use of the medication is canceled and another drug is selected.
Instruction manual
"Binafin" in the form of a cream is not prescribed for patients under 12 years of age. Before applying an antifungal agent, the affected areas of the skin are steamed, the keratinized layer of the epidermis is removed with pumice and dried well. The cream should be applied to the skin with a thin layer, capturing adjacent areas of healthy skin. After treatment, a light massage is performed. Treat the skin affected by the fungus 1-2 times a day. If the product is used once, then it is best to do the treatment before bedtime.
If, in addition to the nails, the fungal infection spreads to the space between the fingers, in the groin area or between the buttocks, and also under the mammary glands, after applying the cream, the skin should be covered with gauze.
After several days of using Binafina, a positive dynamics in the patient's condition is observed. The clinical picture of the disease loses its severity. You can not interrupt the course of treatment with the drug or shorten the prescribed period, as this can lead to re-spread of the fungus.
Smooth skin affected by dermatomycosis is treated within one week. For the treatment of cutaneous candidiasis and multi-colored lichen, approximately two-week Binafin treatment will be needed.
Oral administration
Oral administration of the drug requires longer courses. With onychomycosis, the drug is taken from two to six weeks. If the nail plates on the hands are affected by the fungus, the treatment will take at least 5-6 weeks.
The toenails affected by the fungus take much longer to heal. It is necessary to take tablets for at least three months, especially if the nail plate has the property of slowly growing back. The drug is taken by adults in a dosage of 250 mg. per day.
Reviews about the Binafin tablets from nail fungus will be considered at the end of the article.
Features of the reception
In tablet form, the drug is prescribed for children who are two years old, taking into account the body weight of the child:
- If the child weighs less than 20 kilograms - 62.5 mg per day.
- With a body weight of 20-40 kg - 125 mg per day.
- If the weight is more than 40 kg - 250 mg per day.
Take "Binafin" while carrying a child is allowed only under strict medical supervision. In this case, the doctor must evaluate all possible risks and the appropriateness of the treatment.
If it is necessary to treat onychomycosis during breastfeeding, you should choose another drug, since terbinafine can pass into breast milk. Sometimes it is allowed to interrupt breastfeeding for the period of treatment with "Binafine" with the subsequent restoration of lactation.
The elderly patient does not require adjustment carried out by means of "Binafina" treatment. However, if an elderly patient has a history of liver or kidney disease, the doctor will take this into account when determining the dosage of the drug.
Analogs
If there is intolerance to the components of Binafine, a similar drug should be selected. Among the most effective antifungal agents are the following:
- Lamicon.
- Atifin.
- "Trimistin."
- Futsis.
- "Exifin."
- "Terbizil."
- Klion D
- Mycoderil.
- Ungusan.
- Kanespor.
- "Clotrimazole."
- "Terized Agio."
It is not recommended to choose an antifungal agent on your own. You should consult a specialist, determine the type of fungus and choose a drug whose active component will affect a specific pathogen. The modern pharmaceutical market offers a lot of antifungal drugs, therefore, if this did not fit, it will always be possible to choose a remedy with a similar effect.
Reviews of Binafine should be reviewed in advance.
Cost
This is a fairly common drug, you can find it in almost every pharmacy. The cost of the product is acceptable. 14 tablets of 250 mg on average will cost 500 rubles. Cream at a cost of 350-400 rubles.
Reviews about "Binafine"
Consumers recognize it as one of the most effective drugs with antimycotic effect. It has a fungicidal and fungistatic effect. In the bulk, reviews about the drug are positive, patients describe the high effectiveness of both the cream and the tablet form. The combination of these agents, which is most effective, is especially appreciated. What other reviews are there about Binafine? From nail fungus, it helps very well.
Many people compare it with the antifungal agent Lamisil. The cost of the latter is an order of magnitude higher, however, for some patients, a drug based on terbinafine seemed more effective. Another advantage of the drug is its economical consumption, in which the cream is enough for long-term use.