Enalapril Hexal, also known as Enalapril Hexal, belongs to the group of ACE inhibitors. This abbreviation hides a rather incomprehensible term for a person who does not have a medical education - an angiotensin-converting enzyme. The drug is indispensable in case of pressure problems, due to the presence in its composition of the active component of enalapril maleate. Read how it works below.
The human body is a complex system
In our body, a wide variety of biochemical interactions are constantly ongoing. This allows you to control vital activity at the cellular level, eliminate possible errors, failures, and destroy "aliens" from the outside - microbes, viruses, parasites. The renin-angiotensin-aldosterone system is also a complex interaction of biochemical processes. Here, the active components are converted through several stages of conversion, and each of the steps of this reaction is important for the balance of water and salt in the body, and also controls the level of blood pressure. If the natural control mechanism fails, it needs outside help with medicines that suppress the work of one of the links in the chain or, conversely, enhance the effect of an active biological substance.
Why does Enalapril Hexal help with arterial hypertension? The main component of the drug interacts with angiotensin, one of the most important parts of the above pressure control system. It reduces the activity of a biological compound, and this in a chain has an effect on further processes. In particular, the adrenal glands must produce aldosterone in their cortex, but this does not occur under the influence of the composition of Enalapril Hexal. This effect leads to a decrease in pressure indicators.
Important, useful, irreplaceable
For quite some time now, Enalapril and Enalapril Hexal have become an indispensable element of a first-aid kit for people suffering from pressure problems. The medication is relevant for hypertension. However, hypotensive is not the only effect of regular use. The drug has a positive effect on the heart and improves the quality of the vascular system.
Use according to the testimony of “Enalapril Hexal” allows you to get rid of too much vascular tone. Proper intake reduces the load on the heart muscle. The drug has a diuretic effect, but quite mild.
Convenient in everyday life
What helps Enalapril Hexal? Doctors recommend resorting to this medication for hypertension. Use the tool should be on the recommendation of a doctor, you cannot prescribe it yourself, but in the future, the reception is not always required by the course, it is enough to use it in those moments when there are pronounced problems with pressure.
You will be able to feel the effect of taking the drug after five hours from the moment you use the tablet. Sometimes the result comes a little earlier or later - deviations within an hour. Efficiency persists for 24 hours. Instructions for use "Enalapril Hexal" contains references to the fact that a pronounced clinical effect can be obtained if you regularly use the product for at least six months. This is true for those who suffer from heart failure.
How to use?
When choosing which pressure pills to drink better, it makes sense to pay special attention to the Enalapril Geksal remedy. It is not only effective, but also convenient to use. So, you do not need to adapt to the developed diet or daily routine. It is allowed to use tablets at any time, it does not depend on food intake.
The manufacturer offers several different medication regimens, all of which are indicated in the instructions for use of Enalapril Hexal, enclosed in a package with tablets. Before starting the course, it is recommended to carefully study the information on the insert in order to know how to use the product, and also to check if there are any contraindications.
The easiest way to use the drug is a “solo”. The mechanism is designed to combat hypertension, that is, it answers the question of how to relieve pressure at home quickly. The initial dose according to this scheme is 5 mg. If the expressed effect is absent after a week or even two from the moment of the start of treatment, you can double the daily dose. The maximum amount in 24 hours, as indicated by the instructions for use of Enalapril Hexal, is 40 mg. If this amount of medication does not give a pronounced effect, you should immediately contact your doctor. Increasing the dose further is unacceptable.
Features of the reception
From the reviews of Enalapril Hexal, it follows that the drug has a stronger effect on the elderly. The antihypertensive effect of the intake is expressed more clearly, lasts longer than when using the medication by people of young, middle age. This effectiveness has a scientific explanation: in old age, the body systems responsible for removing the main active component work more slowly, so the substance affects the cardiovascular system longer. This imposes certain restrictions, in particular, on the daily dose. At the beginning of the course of treatment, it is worth starting with 1.25 mg, increasing the volume of the medication as needed.
Instructions for use "Enalapril Hexal" contains a reference to the good compatibility of the drug with other drugs designed to lower blood pressure. You can use the tool as a single medication. The duration of the course is usually determined, focusing on the effectiveness of the drug. As necessary, adjust the dose. If the tool shows low efficiency, it is increased. With a persistent positive effect, you can gradually reduce the amount of medication consumed per day. As a rule, they are reduced to a certain supporting value, and Enalapril Geksal is constantly used in this volume.
Do not let the problem drift
If malfunctions in the cardiovascular system were diagnosed, a person should be aware that this is really dangerous and can be not only a source of everyday troubles, but also life-threatening. If pressure problems have been plagued for a long time, you can cope with them with the help of qualified medical care and the right therapy. Doctors prescribe drugs by conducting a series of laboratory tests. This is important: it is strictly forbidden to prescribe medication yourself, at your own discretion. All known remedies for pressure, including Enalapril Hexal, have contraindications, cases of individual intolerance are known. In order not to make yourself worse, you must first consult a doctor and only after that start treatment, following his instructions.
When patients ask the doctor how to relieve pressure at home quickly, doctors often refer to Enalapril Hexal. Its composition is effective, easy to use. A relatively safe medication comes to the rescue, eliminating pressure problems and compensating for heart failure.
Effect on the body
With a weak effect on the veins, regular use of the drug has an effect on the arteries, expanding them - this is mentioned by the manufacturer in the instructions for use of Enalapril Hexal. At what pressure should the drug be drunk, it is also indicated in the descriptions of the pharmacological company that manufactured the drug.
The judicious use of the medication allows you to adjust the pressure in the atrium on the right. If the ventricle on the left is hypertrophically deformed, regular use of Enalapril Hexal can reduce these distortions. The vessels on the periphery become stronger, the resistance decreases, which generally has a positive effect on blood pressure, and the indicators stabilize.
Important points
If Enalapril Hexal was prescribed, the price of the medicine becomes important information for the patient. Often, the need for the drug occurs in the elderly, forced to save and spend money exclusively with benefit.
On average, in pharmacies in the prices for the current year, the packaging costs about 200 rubles. It contains 20 tablets, each containing 20 mg of the active substance (that is, the initial dose is a quarter of the tablet per day).
Analogs: Enap, Enam, Renitek, Berlipril.
Indications for admission
The need for Enalapril Hexal occurs if a person has been diagnosed with:
- inoperative ventricle on the left;
- arterial hypertension.
To know which pressure pills should be used, it is also necessary for those who have revealed chronic heart failure. The choice of dose remains with the attending physician, this is additionally paid attention to in the instructions and the manufacturer of the medication.
Features of the reception
It has already been mentioned above that the use of Enalapril Hexal is independent of meals. When figuring out how to relieve pressure at home, you need to remember that doctors recommend this particular remedy to drink in the morning, although the condition is not mandatory. Usually the daily dose is drunk at a time, but in some cases they are divided into two doses. As a rule, the attending physician recommends doing so, focusing on the characteristics of the patient's body.
With heart failure, diagnosed in a chronic form, the starting dose of the drug is 2.5 g. Based on the reaction of the body, the dose is increased, but this happens gradually. Understanding how to relieve pressure at home, you need to remember that the chronic form of heart failure imposes serious restrictions on drug therapy, and more than 10 mg of the drug per day can usually not be used. If the pressure remains high and the effectiveness of the tablets is low, you must urgently consult your doctor and describe the problem. The maximum possible dose per day is 20 g.
Other restrictions
If left ventricular dysfunction is diagnosed, the initial dose of the drug is 2.5 mg. Over time, this amount is increased. It is believed that Enalapril Hexal provides supportive therapy if 10 mg of the substance is taken twice a day. The doctor will tell you exactly how much to use at what pressure. Instructions for use "Enalapril Hexal" also contains a mention of the combined effect while taking diuretics: a hypotensive result becomes more pronounced.
What is on sale?
On sale you can find three variants of Enalapril Hexal, which differ from each other in the amount of active ingredient in one tablet. These are the following forms: 5, 10, 20 mg. The product is packaged in cardboard packaging containing several blisters. Each of the blisters is a dozen tablets.
If the amount of active ingredient is minimal, such a tablet has a white color. The average level is colored in a brownish red tint, and the strongest medicines are light orange. In addition to enalapril maleate, "Enalapril Hexal" contains excipients that simplify absorption and improve the effectiveness of the product.
Pharmacological company manufacturing Enalapril Hexal is located in Germany, its name is Salutas Farma GmbH.
Does it fit or not?
It is known that Enalapril Hexal can change the effectiveness of a number of medications if you take these funds at the same time. If the doctor has prescribed this particular drug for pressure, it is necessary to notify him of the complete list of means by which the patient is treated for other health disorders. For example, if you simultaneously use Enalapril Hexal and non-steroidal drugs that fight inflammation, as well as any analgesics, you may encounter a weakening of the effectiveness of high pressure. This is observed when taking aspirin, "Indomethacin." If the doctor knows about the complete list of medicines used by the patient, he can adjust the dose of this or that medicine or even replace something with a more suitable one in this situation.
A number of medications in combination with Enalapril Hexal tablets can lead to the development of leukopenia. This pathology is expressed by a reduced number of white blood cells in the blood. A similar negative effect is provoked by a combination of Enalapril Hexal with:
- anti-immunity drugs;
- corticosteroids of systemic effects on the body;
- cytostatics;
- Novocainamide;
- Allopurinol.
What else is possible?
It has already been indicated above that enhancing the effectiveness of Enalapril Hexal tablets can be achieved by the simultaneous use of diuretics. Anesthetics also activate the drug against high blood pressure. A similar effect can be achieved by combining Enalapril Hexal and other anti-hypertension drugs.
If you eat too much regular dietary salt, the effectiveness of Enalapril Hexal tablets (reviews also say this) is reduced.
Combinations and effects
When combining Enalapril Hexal and diuretics that help preserve potassium, as well as potassium-based drugs, while using the medication in question and the name Heparin, the concentration of potassium in the blood increases. If you combine the intake of Enalapril Hexal and lithium-based medications, the concentration of lithium in the human body increases. This can be diagnosed by taking a blood test.
It is known that Enalapril Hexal can influence if used simultaneously with hypoglycemic drugs. The effect of their intake becomes more pronounced. This applies only to orally administered drugs. This additional effect was revealed when observing patients who used Enalapril Hexal and insulin, as well as those who had to undergo treatment with sulfonylurea products. Doctors note that there is no need to cancel Enalapril Geksala, it is enough to reduce the dose of anti-hypoglycemia medications.
Side effects
Medical statistics show that complications when using Enalapril Hexal tablets are rarely recorded, but there is still a chance of a negative development of events. This is due to the action of the active substance in Enalapril Hexal on the heart and vascular system. If there are negative side effects, then it will be something from the list below:
- general weakness;
- headache;
- vision weakens;
- arterial hypotension;
- angina pectoris;
- heart palpitations;
- thromboembolism (the artery of the lungs is the first to suffer).
In rare cases, the respiratory system suffers in addition to taking Enalapril Hexal tablets. This is expressed by the following manifestations:
- rhinorrhea;
- pharyngitis;
- pneumonia;
- dyspnea;
- spasms of the bronchi;
- dry cough.
I'm allergic!
Such cases are really rarely recorded, but no one is safe from them; allergy is indeed possible. A similar reaction to Enalapril Hexal tablets appears as follows:
- the skin itches, becomes covered with a rash;
- face, legs, arms swell;
- swollen tongue, lips, larynx;
- eczema;
- hives;
- stomatitis;
- photosensitivity.
Side effects: what else is possible?
In some cases, the regular use of Enalapril Hexal can provoke a negative reaction from the nervous system. This is usually expressed as follows:
- dizzy, headache;
- weakness;
- consciousness as if stunned;
- fatigue increases;
- sleep quality is falling;
- cramps.
Depressive disorders and nervousness are possible.
It is known that in a vanishingly small percentage of cases, the use of Enalapril Hexal affects the functioning of the genitourinary system. The drug can negatively affect the kidneys, which leads to proteinuria. If you regularly drink Enalapril Hexal tablets in a large dose, this can increase the risk of impotence. Doctors recommend that while undergoing treatment with Enalapril Hexal, regularly take tests, monitoring the number of platelets, hemoglobin in the blood.
To eliminate the emerging negative side effects, it is enough to stop taking the medication. Almost all negative phenomena disappear immediately.
And when not?
A list of contraindications for Enalapril Hexal can be found in the instructions for use. A doctor who prescribes drugs for high blood pressure is also familiar with them, therefore, the appointment of a medication is made only with prior thorough familiarization with the patient's history. Please note: if the patient is included in the group of persons with contraindications, it is strictly forbidden to use the drug, or possibly under the close supervision of a treating specialist. In no case is it unacceptable to experiment at home, hoping for a chance. This can lead to a serious complication of the situation and even greater health problems.
The list of contraindications:
- minor age;
- impaired functioning of the liver, kidneys;
- artery stenosis in the kidneys (any form);
- hypersensitivity to the components of the drug;
- intolerance to this type of medication (ACE inhibitors).
If in the past the patient has already used ACE inhibitors, and this practice has led to the development of angioneurotic edema, treatment with Enalapril Hexal tablets is strictly prohibited.
Pregnancy and lactation
The use of Enalapril Geksal during this period is categorically not recommended. If a woman used a drug or any other ACE inhibitor while carrying a child, it is necessary to carefully monitor the child. Possible pressure disorders, most often diagnosed with low blood pressure, oliguria, hyperkalemia. In some cases, neurological disorders develop. This is due to the effect on the blood supply to the kidneys, brain - problems arise when pressure is below normal.
If a child has oliguria, supportive therapy should be developed to monitor blood pressure. Additionally, there is a need for renal perfusion. To do this, use means that can narrow blood vessels, as well as special fluids.