Among all drugs that affect tissue metabolism, amino acids occupy a special place. The drug “Cerebrolysin” also belongs to them. The instruction to it recommends using this tool to treat many serious diseases.
This drug belongs to the group of nootropic drugs. Its active substance is a hydrolyzed brain substance freed from proteins. It contains 18 amino acids. So, one milliliter of this product in terms of amino acid content is equivalent to about one gram of brain tissue (fresh).
The drug "Cerebrolysin", the instruction for which recommends using it for intramuscular and intravenous administration, is available in the form of an aqueous solution. It is sold in ampoules (1, 5, 10 ml) and bottles (30, 50 ml). The solution is amber, transparent. 1 ml contains a complex of peptides extracted from the brain of a pig. Excipients are distilled water and sodium hydroxide. The drug "Cerebrolysin" in tablets is not released.
After a single injection of the drug, neurotrophic specific activity persists for almost eight hours.
The drug "Cerebrolysin" - its use is advisable for diseases that cause dysfunction of the central nervous system:
- brain injury (concussion, traumatic brain injury);
- operations on the brain;
- hemorrhages;
- inflammatory processes;
- vegetative dystonia.
The medicine is also used as an adjuvant in the treatment of narcolepsy, minor epilepsy, and with a mild form of mental retardation of children.
Indications for use of this drug are also:
- ischemic stroke;
- consequences of hemorrhagic stroke ;
- decreased attention span in childhood;
- dementia syndrome ;
- Alzheimer's disease;
- cerebrovascular insufficiency;
- endogenous depression (resistant to antidepressants).
The drug "Cerebrolysin", the instructions for which indicate a huge number of diseases in which it can be used, has only a few contraindications:
- acute renal failure;
- hypersensitivity;
- status epilepticus.
With certain caution, this drug is prescribed for pregnant women (extremely rarely in the 1st trimester), nursing mothers and with allergic diathesis. Also, do not forget that this medication significantly enhances the effect of antidepressants when interacting with them.
Side effects: pain during administration, allergic reactions, hyperthermia (with rapid intravenous administration), sweating, constipation, nausea, diarrhea. Arrhythmia, tachycardia, dizziness, agitation, insomnia, apathy, fatigue, arterial hypertension and hypotension are very rare.
There are several schemes by which the drug “Cerebrolysin” is administered.
Instructions for dosage and route of administration
For ischemic stroke, head injury (traumatic brain injury), complications after surgery, the drug is administered intravenously (drip). The duration of the procedure is 1-1.5 hours; dose - 10-60 ml, diluted in 100-250 ml of NaCl solution (0.9%). The duration of therapy is 10-25 days.
With a stroke (residual period), traumatic brain damage, the drug is administered intravenously in 5-10 ml for 20-30 days.
In case of depression and psycho-organic syndrome - 5-10 ml intravenously for 20-25 days (for dementia), 10-15 days (for depression).
Neuropediatric practice - intramuscularly 1-2 ml for thirty days. Repeat this course two to three times a year.
Alzheimer's disease, dementia - intravenously (drip) of 20-30 ml in 100-200 ml of NaCl solution (0.9%) for twenty days.
After opening the ampoules, the solution can not be stored. It must be used immediately. The drug is stored in a dark place at 25 ° C. Duration of storage: five years in ampoules and four years in bottles.