The drug, which will be discussed in this publication, for sure can be purchased at every pharmacy stall. At a price it is available to almost any user, and its effectiveness is time-tested. This medicine is called "Nitroxoline", its use in many people is associated with renal pathologies. In principle, it is, but in general, by its pharmacological action, it is an antimicrobial (antibacterial) drug.
In particular, in terms of its antibacterial effect, the drug is effective both against gram-positive and gram-negative bacteria, a number of Candida fungi and others. Quickly absorbed from the digestive tract, the active substance is excreted from the body by the kidneys almost unchanged. Accordingly, a high concentration of the drug Nitroxoline is noted in the patient's urine.
Indications for use. This drug is prescribed for the treatment of various urinary tract infections. In particular, with the aforementioned renal pathologies, such as inflammation of the renal tissues, pelvis, pyelonephritis. Also, "Nitroxoline", the instructions for use recommends for such inflammatory processes:
- Bladder inflammation (cystitis).
- Inflammatory processes in the urethra (urethritis).
- Inflammatory processes in the prostate gland (prostatitis).
- Epididymitis and others.
The drug under consideration is prescribed a wide spectrum of action by a specialist and with a number of other inflammations of the aforementioned body systems. Also, "Nitroxoline" instructions for use refers to drugs that are effective in the prevention of postoperative infections in the kidneys, urinary tract. It is used as a preventive measure in cystoscopy, catheterization.
The drug has proven itself with respect to microflora, which is resistant to other antibacterial drugs.
The method of use of the drug "Nitroxoline" instructions for use are described as follows. Pills are taken during / after meals. For adult patients, treatment is prescribed for 14-21 days. Four doses of 100 mg per dose are made per day, the maximum daily dose is 800 mg. In normal cases, in relation to the drug "Nitroxoline", the instructions for use indicate the daily dose of the drug is half as much, namely 400 mg.
Not looking at the good tolerability of the described drug, you should not take it spontaneously. In some cases, appropriate specialists increase the daily dose to half a gram. It is forbidden to exceed the previously indicated higher daily dose of Nitroxoline.
For children, starting from 5 years old, the medication for treatment is prescribed based on: the daily dose is 200-400 mg, divided into four doses. Until the age of five, a dose of 200 mg is divided into 4 doses. The duration of therapy is the same as for adult patients - from 14 to 21 days. Chronic infections may require repeated courses of therapy using Nitroxoline with two-week intervals.
The drug, although well tolerated in most cases, can cause some side effects, in particular nausea. And this is one of the reasons that it is better to take this drug during / after meals. As with any other medicine, Nitroxoline (rarely) can cause an allergic reaction in the form of a rash.
Given the possibility of cumulation (accumulation of the active substance in the body), caution is recommended in patients with renal failure. Urine staining in dark yellow is also a feature of therapy with the use of Nitroxoline. This phenomenon does not constitute any danger.
A contraindication to the use of this drug is considered to be only hypersensitivity to drugs of this series.