Everyone knows that it is very difficult to fight fungal diseases, this requires a lot of perseverance. In some cases, even after successful treatment, relapses of this unpleasant pathology occur. That is why it is very important to choose the optimal drug and apply it correctly. Instructions for Exifin will be presented in this article.
Forms of the drug and its composition
This drug is based on terbinafine hydrochloride in the form of tablets or cream (in some cases, the word ointment is used).
Exifin tablets include, in addition to the main component, microcrystalline cellulose, sodium starch glycolate, magnesium stearate, colloidal anhydrous silicon, and pregelatinized starch. The number of tablets in one package varies from sixteen to forty pieces.
Exifin cream (ointment), in addition to the main active ingredient, includes alcohols (benzyl, cetyl, stearyl), sorbitan stearate, cetyl palmitate, sodium hydroxide, polysorbate and purified water. Available in tubes of ten grams.
Pharmacological effect
What does the instruction for Exifin tell us? The action of the drug is based on inhibition of terbinafine and the elimination of pathogens at the cellular level. It disrupts protein biosynthesis in the initial stages.
This medicine is produced in India, which is famous for its achievements in the pharmaceutical industry.
“Exifin” is mainly used for treating skin and nail fungal disorders, mycoses of the mucous membranes provoked by mold, dimorphic, yeast dermatophytes or fungi. Due to the effective counteraction of pathogenic microflora in low concentrations, this drug is used to treat systemic mycoses.
When the drug enters, terbinafine begins to be immediately absorbed, accumulating in the nails, tissues and skin.
Fungicidal effect manifests itself approximately a couple of weeks after the start of its use. During this time, the necessary concentration of the main component is gained. It is metabolized in the liver and leaves the body simultaneously with excretory products, mainly with urine.
When is it used?
According to the instructions, “Exifin” in the form of tablets is used for:
- trichophytic and microscopic syndromes;
- rubrophytes;
- serious dermatomycoses that require a systematic approach to treatment;
- all kinds of candidiasis;
- fungal lesions of the skin areas that are hidden behind the hairy areas of the body;
- systemic mycoses;
- nail and foot fungi.
The use of the drug is prescribed for mycosis of the legs and hands, multi-colored lichen, thrush, inguinal epidermophytosis, fungal infections, diaper rash. This is confirmed by the instruction for Exifin ointment.
Method of using the drug
The duration of the therapeutic course, as well as the dosage of the drug, are determined individually by the attending physician. It depends on the features of the localization of pathogenic manifestations and the severity of the disease.
The normal dose for an adult patient in the treatment with tablets is a single dose of 250 mg per day. Thumb onychomycosis requires three months of therapy. Onychomycosis of the limbs is treated even longer - from six months to a year, which is determined by the age of the victim. Therapy of nail plates affected by the fungus, "Exifin" also depends on their growth rate and varies from one to two months.
According to the instructions for use with Exifin ointment, foot or interdigital fungi can withstand the drug for up to one and a half months. For about a month, the fight against mycosis of the trunk and lower leg continues. A little more time is needed for the treatment of head mycosis. Such a pathology as candidiasis can be cured in 3-4 weeks. In diseases of the liver and kidneys, as well as during treatment of children, it is necessary to reduce the dosage by half. It must be clarified that children's doses are prescribed depending on the body weight of the baby. If the weight does not exceed twenty kilograms, it is equal to a quarter of the tablet.
Cream treatment is also regulated. They need to lubricate both those areas that are affected by the fungus, and the adjacent areas. Before the procedure, you need to carry out hygienic manipulations - treat with an antiseptic and dry the inflamed areas. As the instructions to Exifin indicate, the cream is applied once or twice during the day, depending on the patient’s diagnosis.
The duration of the therapeutic course varies depending on the pathology:
- with candidiasis of the mucous membranes and multi-colored lichen - up to two weeks;
- with epidermophytosis of the groin - up to fifteen days;
- with foot fungi and dermatoses - seven days.
Very often, the feet become infected again. To prevent this, it is recommended to conduct at least two courses, taking a break between them for one week. It should also be remembered that some places on the body are sweating more than others (the space between the buttocks and between the fingers, the area near the chest). In order for therapy to be successful, it is recommended that you cover the oiled areas with gauze or medical dressings before bedtime. What else describes the instructions for use with Exifin?
Possible side effects
Negative effects, including quite serious ones, are most often observed when using tablets, manifesting, in particular, in the form of:
- digestive system disorders;
- depression syndrome;
- arthralgia and myalgia;
- loss of appetite;
- taste receptor disorders;
- urticaria;
- headaches.
In addition, kidney and liver problems may occur. Unfortunately, the list does not end there. To protect yourself from the pathological consequences, you must strictly adhere to the dosage prescribed by the doctor, and never engage in self-medication.
About the cream, it must be said that the situation in this case is more pleasant: after topical application, sensations of slight itching and burning are possible. In addition, rashes may appear. However, all this passes without a trace in a quarter of an hour.
In what cases is the use of the drug not recommended
According to the instructions for Exifin, tablets and other forms are contraindicated in the presence of the following pathologies in the patient:
- partial defects in the functioning of the kidneys or liver;
- neoplasms (both malignant and uncertain);
- metabolic imbalance;
- vascular disease;
- addiction to alcohol;
- treatment during childbearing and breastfeeding;
- individual intolerance of the ingredients in the composition of the drug.
Tablets are prohibited for use with:
- blood pathologies;
- a number of psoriatic rashes;
- categorically can not be used for children who are not two years old.
Therapy with cream is prohibited:
- with defects in the blood circulation of the bone marrow;
- patients under the age of twelve.
Some experts believe that treatment with a cream is possible for pregnant women and nursing mothers in the presence of serious indications for the use of medicines.
"Exifin" during pregnancy
Judging by the data obtained during the experiments, terbinafine does not have a teratogenic effect. To date, no developmental defects that would be due to the use of Exifin have also been reported. But the clinical experience of using the drug in pregnant women is quite limited, and therefore the drug must be used only for strict indications. Terbinafon is characterized by the fact that its excretion is carried out with breast milk, but during the application of the cream by the nursing mother, the absorption of the active component is insignificant, therefore the baby is protected from the expected negative effect.
Analogs
In the medical industry, there are a lot of analogues of Exifin, which also need to be taken only as directed by a doctor. Here are some of them:
- "Lamisil", produced in the form of tablets and ointments;
- Terbinafine also in both forms;
- "Terbizil";
- "Terbifin";
- "Fungoterbin";
- "Thermicon" in the form of a spray or cream.
special instructions
According to the instructions for Exifin cream, patients with psoriasis should be very careful when prescribing terbinafine, since the drug in some cases causes an exacerbation of the pathology. Treatment requires compliance with a number of hygiene standards to exclude the possibility of reinfection through shoes or underwear. Every two weeks it is necessary to do a special antifungal treatment of shoes, stockings and socks. The cream is prescribed only for external use. It is necessary to avoid its penetration into the eyes, since the drug can cause itching and irritation. In case of accidental contact with Exifin's eyes, rinse them and go to the doctor. In case of allergic reactions, the drug should be discontinued. This is confirmed by the instruction.
Reviews about Exifin
Most patients speak positively about Exifine. During therapy, tablets and cream should be used, since the fungus needs an integrated approach, it is necessary to fight it not only from the outside, but also from the inside. Only if this condition is met can one judge positive changes. An allergic reaction to Exifin in the form of urticaria may occur, and during topical use of the ointment, itching and burning. In addition, gastrointestinal complications may appear - diarrhea, nausea, impaired liver function. Patients recommend not to stop treatment too quickly, because in this case, the disease will return again and begin to cause inconvenience. Only after completing the entire course and approaching the treatment comprehensively, you can cope with the pathology.
Some patients are confused by the price of the drug. In addition, some consider it not effective enough.
We reviewed the instructions for the use of Exifin cream.